Wednesday, July 8, 2026

Patent intelligence · US

US 12220446

Use of upstream open reading frame 45aa-uORF nucleotide sequence of PTEN gene and polypeptide coded by 45aa-uORF

granted A61KA61K31/713A61K38/1703A61K38/465
Status granted
Linked drugs 1
Pipeline programs 6
Years to expiry 19
Applicant portfolio 123
Patent details — US 12220446

Quick answer

US 12220446 (Use of upstream open reading frame 45aa-uORF nucleotide sequence of PTEN gene and polypeptide coded by 45aa-uORF) is held by THE FIRST AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY. Status: granted. Granted Feb 11, 2025. Expires Feb 6, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Key facts

Grant date
Expiration
Claims
3
CPC classes
A61K, A61K31/713, A61K38/1703, A61K38/465, A61K48/00, A61P

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Frequently asked questions

What is US patent 12220446?

US 12220446 (Use of upstream open reading frame 45aa-uORF nucleotide sequence of PTEN gene and polypeptide coded by 45aa-uORF) is held by THE FIRST AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY. Status: granted. Granted Feb 11, 2025. Expires Feb 6, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Who owns US 12220446?

THE FIRST AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY is listed as the applicant in USPTO PatentsView records indexed by NovaPharmaNews. We track 123 pharmaceutical patents for this assignee.

When does US 12220446 expire?

Our index shows an expiration date of Feb 6, 2045 (19 years from today). Confirm material dates against USPTO, FDA Orange Book, or qualified counsel before contractual decisions.