Thursday, July 9, 2026

Patent intelligence · US

US 12219327

Substituted isoindolines as PI3K-alpha inhibitors

granted A61KA61K31/4035A61K31/404A61K31/4155
Status granted
Linked drugs 2
Pipeline programs 6
Years to expiry 19
Applicant portfolio 12
Patent details — US 12219327
Jurisdiction
US
Status
granted
Grant date
Feb 4, 2025
Expiration
Jan 30, 2045
Claims
6
CPC classes
A61K, A61K31/4035, A61K31/404, A61K31/4155
View on Google Patents ↗

Quick answer

US 12219327 (Substituted isoindolines as PI3K-alpha inhibitors) is held by Relay Therapeutics, Inc.. Status: granted. Granted Feb 4, 2025. Expires Jan 30, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Key facts

Grant date
Expiration
Claims
6
CPC classes
A61K, A61K31/4035, A61K31/404, A61K31/4155, A61K31/416, A61K31/428

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Frequently asked questions

What is US patent 12219327?

US 12219327 (Substituted isoindolines as PI3K-alpha inhibitors) is held by Relay Therapeutics, Inc.. Status: granted. Granted Feb 4, 2025. Expires Jan 30, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Who owns US 12219327?

Relay Therapeutics, Inc. is listed as the applicant in USPTO PatentsView records indexed by NovaPharmaNews. We track 12 pharmaceutical patents for this assignee.

When does US 12219327 expire?

Our index shows an expiration date of Jan 30, 2045 (19 years from today). Confirm material dates against USPTO, FDA Orange Book, or qualified counsel before contractual decisions.