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Intelligence · Patents

Expiring patents (≤24 months)

Patent cliff watchlist — pharmaceutical patents approaching loss of exclusivity.

Patents
1,253

Quick answer

1,253 pharmaceutical patents in our index expire within the next 24 months. Use year facets below for annual patent-cliff planning linked to company and drug profiles.

  1. DK 0759786

    Somatostatinbindende peptidmetal-chelatkonjugater

    CIS BIO INT [FR] · Granted Mon Jan 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Sun Jan 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 7169411

    Composition for delivery of biological agents and methods for the preparation thereof

    UNIVERSITY OF NEBRASKA BOARD OF REGENTS · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 7169779

    Inhibitors of p38

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 7169384

    Tumor suppressor CAR-1

    The Board of Regents of the University of Texas System · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 7169594

    Diagnosis and treatment of diseases arising from defects in the tuberous sclerosis pathway

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 7169726

    Catalyst for isomerization of solid fischer-tropsch paraffins and method for its production

    KataLeuna GmbH Catalysts · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 7169799

    Process for producing crystal

    Takeda Pharmaceutical Company Limited · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 7169815

    3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 7169798

    Inhibitors of c-Jun N terminal kinases (JNK) and other protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 7169800

    Imidazole compositions useful as inhibitors of protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 7169801

    Histone deacetylase inhibitors

    Takeda San Diego, Inc. · Granted Tue Jan 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 7173027

    Receptor selective cannabimimetic aminoalkylindoles

    UNIVERSITY OF CONNECTICUT · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 7172869

    Methods for transfecting T cells

    United States of America as represented by the Secretary of the Air Force · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 7173112

    Antibody to GALP and uses thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 7173039

    Protein kinase inhibitors

    Theravance, Inc. · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 7172761

    Polyvalent immunogen

    The Regents of the University of California · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 7172768

    Storage stable powder compositions of interleukin-4 receptor

    Nektar Therapeutics · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 7172770

    Mesoporous compositions for use in drug delivery

    The Board of Regents of the University of Texas System · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 7172876

    Method of screening therapeutic agents for nerve degeneration associated diseases

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 7173005

    Insulin and IGF-1 receptor agonists and antagonists

    ANTYRA INC. · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 7173007

    Therapy for microbial infections

    The United States of America as represented by the Department of Veteran Affairs · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 7173062

    Method for the improvement of skin wrinkles using retinyl retinoate

    ENPRANI CO., LTD. · Granted Tue Feb 06 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 7176179

    Selective induction of cell death by delivery of amino-terminal interleukin-1-α pro-piece polypeptide

    The Regents of the University of California · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 7176283

    Protease-activated receptor 3 and uses thereof

    The Regents of the University of California · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 7175830

    Imaging of drug accumulation as a guide to antitumor therapy

    The United States of America, as represented by the Secretary, Health and Human Services · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 7175838

    Use of a promoter of T-cell expansion and an inducer of CD40 stimulation in the treatment or prevention of a pathologic state

    The United States of America represented by the Department of Health and Human Services · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 7175843

    Methods for selectively stimulating proliferation of T cells

    United States of America as represented by the Secretary of the Air Force · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 7175845

    Monoclonal antibodies against ricin toxin and methods of making and using thereof

    The United States of America as represented by the Secretary of the Army · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 7175848

    Ricin A chain mutants lacking enzymatic activity as vaccines to protect against aerosolized ricin

    The Board of Regents of the University of Texas System · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 7175981

    Method of diagnosing stage or aggressiveness of breast and prostate cancer based on levels of fatty acid binding proteins

    The United States of America as represented by the Secretary of the Army · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 7175990

    Method of determining endometrial receptivity

    The Regents of the University of California · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 7176208

    Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 7176010

    Isolated human protein having esterase activity and DNA encoding the same

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 7176019

    RICK3 nucleic acids and proteins

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 7176201

    Modulation of anxiety through blockade of anandamide hydrolysis

    The Regents of the University of California · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 7176211

    Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 7176244

    Use of 2-nitropropanol, 2-nitroethane, and 2-nitroethanol for control of microbial pathogens

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 7176232

    Salinosporamides and methods for use thereof

    The Regents of the University of California · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 7176302

    Liposomal phosphodiester, phosphorothioate, and p-ethoxy oligonucleotides

    The Board of Regents of the University of Texas System · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 7176233

    Salinosporamides and methods for use thereof

    The Regents of the University of California · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 7176280

    Isolated polypeptides and compositions from the venom of P. transvaalicus and methods of use

    The Regents of the University of California · Granted Tue Feb 13 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 7179217

    Apparatus for enhancing tissue repair in mammals

    The United States of America as represented by the Administrator of the National Aeronautics and Space Administration · Granted Tue Feb 20 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 15 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 7179823

    5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 20 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 15 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 7179462

    α (2) macroglobulin receptor as a heat shock protein receptor and uses thereof

    University of Connecticut Health Center · Granted Tue Feb 20 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 15 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 7179826

    Compositions useful as inhibitors of protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 20 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 15 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 7179899

    Composite antibodies of humanized human subgroup IV light chain capable of binding to TAG-72

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Feb 20 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 15 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 7179588

    Assay for the detection of paclitaxel resistant cells in human tumors

    The Board of Regents of the University of Texas System · Granted Tue Feb 20 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 15 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 7179621

    Pigment epithelium-derived factor: sequence of the PEDF gene

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Feb 20 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 15 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is a patent cliff?

A patent cliff is when key pharmaceutical patents expire, opening markets to generics or biosimilars. This hub lists USPTO patents with approaching expiration dates.

Are expiration dates estimates?

Expiration dates derive from USPTO PatentsView grant dates and term estimates. Confirm with Orange Book, patent counsel, and USPTO records before investment decisions.

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