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Intelligence · Patents

Expiring patents (≤24 months)

Patent cliff watchlist — pharmaceutical patents approaching loss of exclusivity.

Patents
1,253

Quick answer

1,253 pharmaceutical patents in our index expire within the next 24 months. Use year facets below for annual patent-cliff planning linked to company and drug profiles.

  1. US 7319015

    Methods and compositions for using alveolar macrophage phospholipase A2

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 7319000

    Compositions and methods for eliciting immune or anti-infective responses

    The Board of Regents of the University of Texas System · Granted Tue Jan 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 7319091

    Human derived monocyte attracting purified protein product useful in a method of treating infection and neoplasms in a human body, and the cloning of full length cDNA thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 7319134

    Regulation of transcription factor, NF-IL6/LAP

    The Regents of the University of California · Granted Tue Jan 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 7319171

    Sertraline hydrochloride form II and methods for the preparation thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jan 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. AU 2007271920

    Benzyl amines, a process for their production and their use as anti-inflammatory agents

    BAYER SCHERING PHARMA AG [SE] · Granted Thu Jan 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 7321063

    Sulfonamide inhibitors of aspartyl protease

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 22 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 7321065

    Thyronamine derivatives and analogs and methods of use thereof

    The Regents of the University of California · Granted Tue Jan 22 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 7320990

    Crystalline form of a biphenyl compound

    Theravance, Inc. · Granted Tue Jan 22 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 7320991

    Analogs of thalidomide as potential angiogenesis inhibitors

    The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer · Granted Tue Jan 22 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 7320783

    Methods and compositions for the enhancement of wound healing

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 22 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 7320965

    Compositions and methods for inhibiting expression of Huntingtin gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jan 22 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 7323174

    Modulation of immune response and methods based thereon

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 7323541

    Polypeptide DNA thereof and use of the same

    Takeda Pharmaceutical Company Limited · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 7323165

    Production of pancreatic islet cells and delivery of insulin

    The Regents of the University of California · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 7323297

    Stabilized polynucleotide complexes and methods

    The Regents of the University of California · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 7323166

    Lactic acid bacteria cultures that inhibit food-borne pathogens

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 7323171

    Methods of treating skin conditions using inhibitors of the CD2/LFA-3 interaction

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 7323173

    Methods for treating breast cancer using a mammary cell growth inhibitor

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 7323334

    Screening and therapeutic methods relating to neurogenesis

    The Regents of the University of California · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 7323340

    Compositions and methods for regulating bacterial pathogenesis

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 7323459

    Crystal forms, methods for their preparation and method for preparation of olanzapine

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 7323616

    Genetically altered mice deficient in functional caspase-9

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. EP 1882730

    Systemreinigerkonzentrat

    AIR LIQUIDE SANTE INT [FR] · Granted Wed Jan 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Jan 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 7326695

    Anti-bacterial agents based upon oxoanion binding

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Feb 05 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 7326691

    Compositions comprising amphotericin B, methods, and systems

    Nektar Therapeutics · Granted Tue Feb 05 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 7326542

    Compositions and methods for regulating bacterial pathogenesis

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Feb 05 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 7326570

    Induction of tubular morphogenesis using pleiotrophin

    The Regents of the University of California · Granted Tue Feb 05 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 7326790

    Diphenylisoxazole compounds and hydro isomers thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 05 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 7326697

    Methods for increasing the therapeutic response to electroconvulsive therapy

    Corcept Therapeutics Incorporated · Granted Tue Feb 05 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 7326712

    Substituted tricyclic compounds as protein kinase inhibitors

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 05 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 7326713

    Substituted tricyclic compound as protein kinase inhibitors

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 05 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 7326734

    Treatment of bladder and urinary tract cancers

    The Regents of the University of California · Granted Tue Feb 05 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 7329652

    Diaminotriazole compounds useful as protein kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 7329681

    Inhibitors of IMPDH enzyme

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 7329759

    Illudin analogs useful as antitumor agents

    The Regents of the University of California · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 7329401

    Cyclooxygenase-2 selective agents useful as imaging probes and related methods

    The Regents of the University of California · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 7329642

    β-2-glycoprotein is an inhibitor of angiogenesis

    The Board of Regents of the University of Texas System · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 7329502

    ZAP-70 expression as a marker for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 7329752

    Carbamate compounds as 5-HT4 receptor agonists

    Theravance, Inc. · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 7329511

    Nucleic acid encoding GAD65

    The Regents of the University of California · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 7329638

    Drug delivery compositions

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 7329651

    Cannabimimetic ligands

    UNIVERSITY OF CONNECTICUT · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 7329669

    Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 7329671

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 7329672

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 7329721

    Maleamic acid polymer derivatives and their bioconjugates

    Nektar Therapeutics AL, Corporation · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 7329680

    Heterocycle substituted carboxylic acids

    The Institute for Pharmaceutical Discovery, LLC · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is a patent cliff?

A patent cliff is when key pharmaceutical patents expire, opening markets to generics or biosimilars. This hub lists USPTO patents with approaching expiration dates.

Are expiration dates estimates?

Expiration dates derive from USPTO PatentsView grant dates and term estimates. Confirm with Orange Book, patent counsel, and USPTO records before investment decisions.

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