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Intelligence · Patents

Expiring patents (≤24 months)

Patent cliff watchlist — pharmaceutical patents approaching loss of exclusivity.

Patents
1,230

Quick answer

1,230 pharmaceutical patents in our index expire within the next 24 months. Use year facets below for annual patent-cliff planning linked to company and drug profiles.

  1. US 7241799

    Cannabimimetic indole derivatives

    UNIVERSITY OF CONNECTICUT · Granted Tue Jul 10 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 05 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 7241571

    Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis

    The Regents of the University of California · Granted Tue Jul 10 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 05 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 7241739

    Morphogenic protein

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 10 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 05 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 7241581

    Methods of identifying compounds that modulate IL-4 receptor-mediated IgE synthesis utilizing a c-MYC protein

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 10 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 05 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 7241746

    Method and composition for treating periodontal disease

    Regena Therapeutics LC · Granted Tue Jul 10 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 05 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 7241796

    Inhibitors of serine proteases, particularly HCV NS3-NS4A protease

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 10 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 05 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 7241783

    Thrombopoietin mimetics

    Ligand Pharmaceuticals Incorporated · Granted Tue Jul 10 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 05 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 7241860

    Transcription factor polypeptide that regulates Chondromodulin-I expression

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 10 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 05 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 7241867

    Polypeptide encoded by a nucleotide sequence of a nontypeable strain of Haemophilus influenzae genome

    The Board of Regents of the University of Oklahoma · Granted Tue Jul 10 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 05 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 7244724

    Pyrrolobenzodiazepines

    THE UNITED STATES OF AMERICA, represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 7244705

    Polyacid glycopeptide derivatives

    Theravance, Inc. · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 7244769

    Methods for treating an impairment in memory consolidation

    Cognition Pharmaceuticals, LLC · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 7244557

    Method of screening modulators of Nod1 signaling

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 7244450

    Compositions and methods for treating lymphoma

    The Board of Regents of the University of Texas System · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 7244448

    Liposomal antineoplastic drugs and uses thereof

    Tekmira Pharmaceuticals Corporation · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 7244423

    Methods for therapy of neurodegenerative disease of the brain

    The Regents of the University of California · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 7244435

    DNA vaccine expressing HA1 of equine-2 influenza virus

    The Board of Regents for Oklahoma State University · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 7244558

    Production of novel Newcastle disease virus strains from cDNAs and improved live attenuated Newcastle disease vaccines

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 7244576

    Modulators of angiogenesis

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 7244617

    Diminishing viral gene expression by promoter replacement

    The Board of Regents of the University of Texas System · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 7244735

    Heterocyclic protein kinase inhibitors and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 7244741

    Fredericamycin derivatives as medicaments for treating tumours

    Biofrontera Discovery GmbH · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 7244760

    Methods for preparation and use of psorospermin analogs

    The Board of Regents of the University of Texas System · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 7244826

    Internalizing ERB2 antibodies

    The Regents of the University of California · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 7244844

    Reference standard for characterization of rosuvastatin

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jul 17 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 12 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 7247615

    Peptide agonists of prostate-specific antigen and uses therefor

    THE UNITED STATES OF AMERICA, represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 7247303

    Selected antibody CDRs for binding to aminophospholipids

    The Board of Regents of the University of Texas System · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 7247307

    Vaccines against Escherichia coli O157 infection

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 7247316

    Compositions and methods for treating lymphoma

    The Board of Regents of the University of Texas System · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 7247705

    Proteins having glucose transporter activity

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 7247653

    Pharmaceutical composition

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 7247708

    Modified vitamin K-dependent polypeptides

    Regents of the University of Minnesota · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 7247707

    Albumin-free factor VIII formulations

    UNIVERSITY OF CONNECTICUT · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 7247716

    Recombinant sequence, its preparation and use

    University College Cardiff Consultants Limited · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 7247751

    Processes for preparing cinacalcet hydrochloride crystal Form I

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 7250169

    Anti-tumor activity of Ea-4-peptide of pro-IGF-1

    UNIVERSITY OF CONNECTICUT · Granted Tue Jul 31 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 7250272

    G protein-coupled receptor protein and DNA thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 31 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 7250182

    Medicament containing Epimedium extract for treatment of prostatic hyperplasia and prostatitis

    Bright Future Pharmaceutical Laboratories · Granted Tue Jul 31 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 7250414

    Diphenylmethyl compounds useful as muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Jul 31 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 7250171

    Construction and use of recombinant parainfluenza viruses expressing a chimeric glycoprotein

    The United States of America as represented by the Secretary of the Dept. of Health & Human Services · Granted Tue Jul 31 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 7250400

    Peptides and derivatives thereof showing cell attachment, spreading and detachment activity

    REGENBiotech, Inc. · Granted Tue Jul 31 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 7250520

    Processes for preparing pyrroles

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 31 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 7252817

    Viruses for the treatment of cellular proliferative disorders

    ONCOLYTICS BIOTECH INC. · Granted Tue Aug 07 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 7253187

    Heterocyclic inhibitors of ERK2 and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 07 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 7253275

    Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia

    The Regents of the University of California · Granted Tue Aug 07 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 7252819

    Methods and compositions for correction of cardiac conduction disturbances

    The Regents of the University of California · Granted Tue Aug 07 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 7252989

    Adenovirus supervector system

    The Board of Regents of the University of Texas System · Granted Tue Aug 07 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 7253147

    Modified serum albumin with reduced affinity for nickel and copper

    New Century Pharmaceuticals, Inc. · Granted Tue Aug 07 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is a patent cliff?

A patent cliff is when key pharmaceutical patents expire, opening markets to generics or biosimilars. This hub lists USPTO patents with approaching expiration dates.

Are expiration dates estimates?

Expiration dates derive from USPTO PatentsView grant dates and term estimates. Confirm with Orange Book, patent counsel, and USPTO records before investment decisions.

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