Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2044

Annual patent cliff calendar for 2044 — US pharmaceutical patents by expiration date.

Patents
1,766

Quick answer

1,766 indexed pharmaceutical patents have expiration dates in 2044. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 12098141

    Bicyclic indazole glucocorticoid receptor antagonists

    Corcept Therapeutics Incorporated · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12097213

    Sequential treatment of cancers using 6-thio-dG, checkpoint inhibitors and radiation therapy

    The Board of Regents of the University of Texas System · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12097199

    Administration of SUMO-activating enzyme inhibitor and anti-CD20 antibodies

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12097188

    Compositions and methods for the treatment of macular degeneration

    Aldeyra Therapeutics, Inc. · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12097185

    Compositions comprising ciprofloxacin and celecoxib

    NEUROSENSE THERAPEUTICS LTD. · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 12097183

    Pharmaceutical composition for treating migraine

    Tonix Medicines, Inc. · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 12098152

    Methods and compositions for treating polycystic ovary syndrome

    SPRUCE BIOSCIENCES, INC. · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 12097291

    Thermostable vaccine compositions and methods of preparing same

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 12097219

    Single-domain antibodies against CLL1 and constructs thereof

    Legend Biotech Ireland Limited · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 12097210

    Concomitant administration of glucocorticoid receptor modulators and CYP3A inhibitors

    Corcept Therapeutics Incorporated · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 12097198

    Treatment of prostate cancer

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. WO 2024194388

    PREPARATION DE LEVURE SACCHAROMYCES BOULARDII INACTIVEE

    BIOCODEX [FR] · Granted Thu Sep 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 12102671

    Method of vaccination with an attenuated RSV vaccine formulation

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 12103958

    Lymphocyte function-associated antigen 3 (LFA3) variant polypeptides and methods of use thereof to treat CD2-mediated immune diseases, disorders or conditions

    The Regents of the University of California · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 12103926

    Compounds for treating huntington's disease

    PTC THERAPEUTICS, INC. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 12103960

    VEGF traps and mini-traps and methods for treating ocular disorders and cancer

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 12104165

    Adeno-associated virus with engineered capsid

    Tenaya Therapeutics, Inc. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 12104172

    Processes for generating TIL products enriched for tumor antigen-specific t-cells

    Iovance Biotherapeutics, Inc. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 12104185

    PH20 polypeptide variants, formulations and uses thereof

    HALOZYME, INC. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 12102682

    Injectable photothermal hydrogel based on melanin, preparation method, and application thereof

    OCEAN UNIVERSITY OF CHINA · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 12102640

    Use of dopamine and serotonin receptor antagonists for treatment in a subject with retinal degeneration

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 12102619

    Methods of treating tuberous sclerosis complex with cannabidiol and everolimus

    JAZZ PHARMACEUTICALS RESEARCH UK LIMITED · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 12102642

    Treatment of hypercoagulopathy in Cushing's syndrome by administration of glucocorticoid receptor modulators

    Corcept Therapeutics Incorporated · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 12102662

    Methods for storing and warming purified corticotropin compositions

    ANI Pharmaceuticals, Inc. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 12102637

    Pharmaceutical formulations for treating endometriosis, uterine fibroids, polycystic ovary syndrome or adenomyosis

    Neurocrine Biosciences, Inc. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 12102609

    Methods of administering solriamfetol to lactating women

    AXSOME MALTA LTD. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 12102668

    Process, tube and device for the preparation of wound healant composition

    RegenLab USA LLC · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 12102646

    Compositions for the treatment of fibrosis and inflammation

    Viking Therapeutics, Inc. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 12102688

    Immunomodulatory nanofilaments

    Stichting Radboud universitair medisch centrum · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 12102617

    Antimicrobial compositions containing a synergistic combination of activated creatinine and an imidazole antifungal agent

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 12103907

    Tetralin and tetrahydroquinoline compounds as inhibitors of HIF-2alpha

    Arcus Biosciences, Inc. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 12102687

    Muscle targeting complexes and uses thereof for treating myotonic dystrophy

    Dyne Therapeutics, Inc. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 12104163

    Adeno-associated virus vectors for treatment of Rett syndrome

    Sarepta Therapeutics, Inc. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 12104184

    PH20 polypeptide variants, formulations and uses thereof

    HALOZYME, INC. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 12104188

    Modified caspase-9 polypeptides and methods of use thereof

    Allogene Therapeutics, Inc. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 12102606

    Dosage forms and methods for enantiomerically enriched or pure bupropion

    AXSOME THERAPEUTICS, INC. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 12104181

    Compositions and methods for treating viral infections targeting TRIM7

    The Board of Regents of the University of Texas System · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 12103978

    Methods and materials for treating cancer

    SHANGHAI MIRACOGEN INC. · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 12102694

    Radiolabeled compound producing method and producing apparatus, radiolabeled compound and radioisotope producing apparatus

    NATIONAL INSTITUTES FOR QUANTUM SCIENCE AND TECHNOLOGY · Granted Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. WO 2024206551

    COMPOSITIONS ET PROCÉDÉS DE RÉHYDRATATION D'ALGUES MARINES

    ABBOTT LAB [US] · Granted Thu Oct 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. AU 2023244944

    PRODRUGS OF OPICAPONE

    BIAL PORTELA & CA SA [PT] · Granted Thu Oct 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 2024327366

    POLYMORPH FORM OF PITOLISANT HYDROCHLORIDE

    BIOPROJET PHARMA [FR] · Granted Thu Oct 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. WO 2024200854

    ANTICORPS DE LIAISON AUX ALLERGÈNES APPROPRIÉS POUR TRAITER DES ALLERGIES AU POLLEN D'ARBRE

    ALK ABELLO AS [DK] · Granted Thu Oct 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. PT 3721882

    TREATMENT OF METABOLIC DISORDERS IN EQUINE ANIMALS

    BOEHRINGER INGELHEIM VETMEDICA GMBH [DE] · Granted Fri Oct 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Sep 29 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. IT 202300006237

    COMPOSIZIONI NUTRACEUTICHE PER IL TRATTAMENTO O PREVENZIONE DI DISORDINI CONNESSI ALLA TRIMETILAMINURIA.

    ALFASIGMA SPA [IT] · Granted Sun Oct 06 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Sat Oct 01 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 12110334

    Neutralizing antibodies to the αvβ8 integrin complex for immunotherapy

    The Regents of the University of California · Granted Tue Oct 08 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 03 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 12110315

    Fish-derived peptidoglycan recognition protein mutant and application thereof

    OCEAN UNIVERSITY OF CHINA · Granted Tue Oct 08 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 03 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 12110344

    Antibodies that bind to cis and uses thereof

    DIANTHUS THERAPEUTICS OPCO, INC. · Granted Tue Oct 08 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 03 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2044?

1,766 published patents in our USPTO index have expiration dates falling in calendar year 2044.