Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2044

Annual patent cliff calendar for 2044 — US pharmaceutical patents by expiration date.

Patents
1,766

Quick answer

1,766 indexed pharmaceutical patents have expiration dates in 2044. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11981724

    DNA antibody constructs for use against middle east respiratory syndrome coronavirus

    Inovio Pharmaceuticals, Inc. · Granted Tue May 14 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11981716

    Activatable interleukin-2 polypeptides and methods of use thereof

    Werewolf Therapeutics, Inc. · Granted Tue May 14 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11981684

    Macrocyclic compounds and uses thereof

    TURNING POINT THERAPEUTICS, INC. · Granted Tue May 14 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11981700

    Pyrrolopyrimidine nucleosides and analogs thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 14 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11981662

    Pyrazole derivatives with anticancer activity

    The Board of Regents of the University of Texas System · Granted Tue May 14 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11981571

    Identification and optimization of carbon radicals on hydrated graphene oxide for ubiquitous antibacterial coatings

    The Regents of the University of California · Granted Tue May 14 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11980659

    Consensus prostate antigens, nucleic acid molecule encoding the same and vaccine and uses comprising the same

    Inovio Pharmaceuticals, Inc. · Granted Tue May 14 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11980636

    Treatment of hematological disorders

    Jazz Pharmaceuticals Ireland Limited · Granted Tue May 14 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11980633

    Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue May 14 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11986449

    Levodopa dosing regimen

    AMNEAL PHARMACEUTICALS LLC · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11987600

    Contraceptive use of triterpenoids

    The Regents of the University of California · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11986561

    Wound dressings and applications thereof

    The Board of Regents of the University of Texas System · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11986442

    Inhibition of respiratory complex III by ligands that interact with a regulatory switch

    The Regents of the University of California · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11986515

    Treatment of mucopolysaccharidosis II with recombinant human iduronate-2-sulfatase (IDS)

    REGENXBIO INC. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11986533

    Macromonomers and bottle brush polymers for delivery of biological agents

    Regents of the University of Minnesota · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11987610

    T-cell modulatory multimeric polypeptides and methods of use thereof

    Cue Biopharma, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11986517

    Cancer vaccines targeting mesothelin and uses thereof

    Inovio Pharmaceuticals, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11986446

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Jazz Pharmaceuticals Ireland Limited · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11987590

    Compounds that participate in cooperative binding and uses thereof

    Revolution Medicines, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11987792

    Compositions and methods for inhibiting expression of the LECT2 gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11987821

    Compositions and methods for treating mitochondrial neurogastrointestinal encephalopathy

    Entrada Therapeutics, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11987628

    Methods and compositions for modulating CAR-T activity

    Sana Biotechnology, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11987548

    Methods of making bempedoic acid and compositions of the same

    Esperion Therapeutics, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11987586

    Pyrrolo[1,2-c]imidazole derivatives as orexin type 2 receptor agonists

    Takeda Pharmaceutical Company Limited · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11986537

    Muscle targeting complexes and uses thereof for treating dystrophinopathies

    Dyne Therapeutics, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11986534

    Treatment of anthrax with pegylated capsule-degrading enzyme

    The Government of the United States of America, as represented by the Secretary of the Navy · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11986471

    Compounds and methods of use

    Tango Therapeutics, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11986511

    Use of a VEGF antagonist to treat angiogenic eye disorders

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11986454

    Methods of providing solriamfetol therapy to subjects with impaired renal function

    AXSOME MALTA LTD. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11986455

    Methods of providing solriamfetol therapy to subjects with impaired renal function

    AXSOME MALTA LTD. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11986481

    Method of synthesizing thyroid hormone analogs and polymorphs thereof

    Madrigal Pharmaceuticals, Inc. · Granted Tue May 21 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 2024166750

    GLYCOENGINEERED Fc VARIANT POLYPEPTIDES WITH ENHANCED EFFECTOR FUNCTION

    ABLYNX NV [BE] · Granted Thu May 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. AU 2022263543

    Pharmaceutical compositions comprising sorbitan esters

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu May 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11993584

    Solid forms of an azolopyrimidine compound

    Arcus Biosciences, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11993660

    Chimeric polypeptides and methods of altering the membrane localization of the same

    Cell Design Labs, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11992506

    Stem cell derived pancreatic islet differentiation

    Vertex Pharmaceuticals Incorporated · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11992555

    Solid solution compositions and use in chronic inflammation

    Infirst Healthcare Limited · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11993640

    Treating inflammatory lung disease

    United States Government as represented by the Department of Veterans Affairs · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11993641

    Methods for modulating an immune response

    Cue Biopharma, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11993594

    IRAK inhibitors and method for making and using

    Rigel Pharmaceuticals, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11993793

    Polynucleotides encoding engineered meganucleases having specificity for recognition sequences in the dystrophin gene

    Precision BioSciences, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11992528

    Compositions and methods for conjugating activatable antibodies

    CytomX Therapeutics, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11993573

    Chromane-substituted, tetrahydroquinoline-substituted and thiochromane-substituted heteroarotinoids as anti-cancer agents

    The Board of Regents for Oklahoma State University · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11992532

    Hydrogels and methods of using the same

    The Regents of the University of California · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11992495

    Enhancing GABA's ability to modulate immune responses

    The Regents of the University of California · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11992480

    Method for reducing side effects from administration of phosphodiesterase-4 inhibitors

    ARCUTIS BIOTHERAPEUTICS, INC. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11992472

    Compositions and methods for enhancing the efficacy of contraceptive microbicides

    Evofem, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11993655

    Anti-PD-L1 antibody and use thereof

    Oricell Therapeutics Co., Ltd. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2044?

1,766 published patents in our USPTO index have expiration dates falling in calendar year 2044.