Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2042

Annual patent cliff calendar for 2042 — US pharmaceutical patents by expiration date.

Patents
1,738

Quick answer

1,738 indexed pharmaceutical patents have expiration dates in 2042. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11478245

    Surgical stapling device

    Covidien LP · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11478420

    Vaginal probiotic products and related processes

    Grace Procurements LLC · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11478424

    Mechanochemcial activated dry amorphisation by milling equilibrium between AP mesoporous silica

    Grace GmbH · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11478428

    Combinations of beta-lactam compounds and probenecid and uses thereof

    Iterum Therapeutics International Limited · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11478479

    Dosing with an azolopyrimidine compound

    Arcus Biosciences, Inc. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11478430

    Implantable medical devices for extended release of therapeutic agents

    Nano Precision Medical, Inc. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11478489

    Selective accretion of cytoprotectant in radiation-sensitive tissues and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11478502

    Methods and compositions for administration of iron

    American Regent, Inc. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11478497

    Methods and compositions for treating eukaryotic infections via altering aggregation dynamics of Raptor/KOG1

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11478517

    Live attenuated recombinant HMPV with mutations in PDZ motifs of M2-2 protein, vaccine containing and use thereof

    The Board of Regents of the University of Texas System · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11478510

    Chimeric antigen receptor and methods of use thereof

    The Regents of the University of California · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11478500

    Anticancer compositions and methods for making and using them

    The Regents of the University of California · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11478571

    Synthetic hydrogel carriers for cellular structures, generation of organoids, and treatment of tissue injury

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11479551

    MTA-cooperative PRMT5 inhibitors

    Mirati Therapeutics, Inc. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11479601

    Antibodies specific to Sonic Hedgehog and method of use thereof

    The Regents of the University of California · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11479770

    Use of p38 inhibitors to reduce expression of DUX4

    Fulcrum Therapeutics, Inc. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11479543

    Heterocyclic RIP1 kinase inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11478541

    Method for inactivating Zika virus and for determining the completeness of inactivation

    Takeda Vaccines, Inc. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11478556

    Compositions and methods for treating or ameliorating neuroinflammation, neurodegeneration, neuropathic pain, and migraine

    The Regents of the University of California · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11479540

    Nonpeptide somatostatin type 5 receptor agonists and uses thereof

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11479530

    Synthetic sphingolipid-like molecules, drugs, methods of their synthesis and methods of treatment

    The Regents of the University of California · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11478568

    Radioactive cement

    The Regents of the University of California · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11479560

    OX2R compounds

    The Board of Regents of the University of Texas System · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11479545

    Compositions and methods for inhibiting phenyl triazole MLL1-WDR5 protein-protein interaction

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11479576

    Nucleic acid prodrugs

    AVALO THERAPEUTICS, INC. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11479556

    Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway

    NURIX THERAPEUTICS, INC. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11479595

    Methods for modulating an immune response

    Cue Biopharma, Inc. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11479617

    Chelator-functionalized glycosaminoglycans

    UNIVERSITY OF CONNECTICUT · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11479602

    Methods of treating C5-associated diseases comprising administering anti-C5 antibodies

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11479611

    HLA-G specific chimeric antigen receptor, nucleic acid, HLA-G specific chimeric antigen receptor expression plasmid, HLA-G specific chimeric antigen receptor expressing cell, use thereof, and pharmaceutical composition for treating cancer

    China Medical University Hospital · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11479613

    Methods for treating cancer or modulating T cells or NK cells in a subject by administering cells comprising chimeric transmembrane proteins

    AUTOLUS LIMITED · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11479614

    Methods for treating cancer or modulating T cells or NK cells in a subject with cancer by administering cells comprising chimeric cytokine receptors

    AUTOLUS LIMITED · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11479769

    Technique for treating cancer using structurally-reinforced S-TuD

    GeneDesign, Inc. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11479774

    Methods of treating cancer harboring hemizygous loss of TP53

    The Board of Regents of the University of Texas System · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11479775

    RNA targeting of mutations via suppressor tRNAs and deaminases

    The Regents of the University of California · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11479771

    Antisense oligonucleotides for the treatment of eye disease

    ProQR Therapeutics II B.V. · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11479772

    Thiomorpholino oligonucleotides for the treatment of muscular dystrophy

    The Regents of the University of Colorado · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11479794

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11478511

    Lymphocyte biomarkers for determining the clinical response to cell therapy

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11478542

    Immunogenic RSV polypeptides

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11478425

    Extended release compositions comprising pyridostigmine

    Amneal Complex Products Research LLC · Granted Tue Oct 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. WO 2022226311

    COMPOSITIONS NUTRITIONNELLES COMPRENANT DES OLIGOSACCHARIDES DE LAIT HUMAIN ET UN CONSTITUANT LIPIDIQUE DÉSIGNÉ D'AMÉLIORATION DE FONCTION PULMONAIRE

    ABBOTT LAB [US] · Granted Thu Oct 27 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 22 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. WO 2022225779

    MÉTHODES ET COMPOSITIONS PERMETTANT DE FAVORISER LA CICATRISATION DE PLAIES

    ABBOTT LAB [US] · Granted Thu Oct 27 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 22 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11485813

    Resin composition for stereolithography

    KURARAY NORITAKE DENTAL INC. · Granted Tue Nov 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11484525

    Mu opioid receptor modulators

    The Regents of the University of California · Granted Tue Nov 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11485788

    Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R inhibitor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11485739

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Nov 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11484501

    Mechanochemical activated dry amorphisation by milling equilibrium between ap mesoporous silica

    Grace GmbH · Granted Tue Nov 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2042?

1,738 published patents in our USPTO index have expiration dates falling in calendar year 2042.