Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2042

Annual patent cliff calendar for 2042 — US pharmaceutical patents by expiration date.

Patents
1,738

Quick answer

1,738 indexed pharmaceutical patents have expiration dates in 2042. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11376263

    Cyproterone acetate compositions and uses thereof

    Fortress Biotech, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11377444

    Pyridopyrimidine compounds acting as mTORC 1/2 dual inhibitors

    Medshine Discovery Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11377447

    Targeted therapeutics

    Madrigal Pharmaceuticals, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11377451

    Compositions and methods for treating cancer

    The Regents of the University of California · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. CA 3203431

    PROCEDES D'AMELIORATION DE RENDEMENT MUSCULAIRE OU DE REDUCTION DE FATIGUE CHRONIQUE PAR ADMINISTRATION D'EXOSOMES DERIVES DU LAIT BOVIN

    ABBOTT LAB [US] · Granted Thu Jul 07 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jul 02 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. CA 3203434

    PROCEDE D'AMELIORATION DE LA SANTE ARTICULAIRE PAR ADMINISTRATION D'EXOSOMES DERIVES DU LAIT DE VACHE

    ABBOTT LAB [US] · Granted Thu Jul 07 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jul 02 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11385201

    Ultra-stable protein ionic liquids

    United States of America as represented by the Secretary of the Air Force · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11384337

    Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11384098

    Pyrrolobenzodiazepine-antibody conjugates

    ADC THERAPEUTICS SA · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11384076

    Synthesis, pharmacology and use of new and selective FMS-like tyrosine kinase 3 (FLT3) FLT3 inhibitors

    Universität Regensburg · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11384065

    Heterocyclic compound as CSF-1R inhibitor and use thereof

    Medshine Discovery Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11384055

    Glycolate oxidase inhibitors for the treatment of disease

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11384062

    Deuterated (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide

    CombiPhos Catalysts, Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11382989

    Engineered microbial population

    The Board of Regents of the University of Texas System · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11382979

    Biodegradable lipids for the delivery of active agents

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11382955

    Long-acting VEGF inhibitors for intraocular neovascularization

    The Regents of the University of California · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11382932

    Genetically engineered hematopoietic stem cells and uses thereof

    Vor Biopharma Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11382976

    Ultra-stable protein ionic liquids

    United States of America as represented by the Secretary of the Air Force · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11382929

    Compositions and methods to treat disease

    Regents of the University of Minnesota · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11382918

    Methods for treating Huntington's Disease

    PTC THERAPEUTICS, INC. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11382899

    Enhanced delivery of immunosuppressive drug compositions for pulmonary delivery

    The Board of Regents of the University of Texas System · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11382885

    Compositions for treating fungal and bacterial biofilms and methods of using the same

    The Regents of the University of California · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11382897

    Therapeutic combination for treatment of cerebellar ataxia

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11382880

    Method for improving digestive health

    Brightseed, Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11385233

    Methods of depleting malignant T-cells

    AUTOLUS LIMITED · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11384355

    Compositions and methods for inhibiting gene expression of alpha-1 AntiTrypsin

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11384350

    Cytotoxic molecules responsive to intracellular ligands for selective T cell mediated killing

    The Regents of the University of California · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11384335

    Genetically-modified immune cells comprising a microRNA-adapted shRNA (shRNAmiR)

    Precision BioSciences, Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11384154

    Targeted chimeric proteins and uses thereof

    Orionis Biosciences, Inc · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11384153

    Bispecific anti-BCMA x anti-CD3 antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11384139

    Antibody targeting cell surface deposited complement protein C3d and use thereof

    THE UNITED STATES OF AMERICA, represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11382981

    Exon skipping oligomer conjugates for muscular dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11382922

    Aqueous oral pharmaceutical suspension compositions

    ReveraGen BioPharma, Inc. · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11382890

    Prevention of rosacea inflammation

    The Regents of the University of California · Granted Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. CA 3207179

    METHODES DE TRAITEMENT DE LA MALADIE DE CROHN ET DE LA COLITE ULCEREUSE

    ABBVIE INC [US] · Granted Thu Jul 14 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jul 09 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11390687

    Bispecific antibodies against plasma kallikrein and Factor XII

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11390861

    CRISPR/cas-related methods and compositions for treating herpes simplex virus

    Editas Medicine, Inc. · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11389517

    Peptide conjugated particles

    Northwestern University · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11389566

    Method and composition for treating inflammatory bowel disease

    Regentys Corporation · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11389490

    Synergistic bacterial compositions and methods of production and use thereof

    Seres Therapeutics, Inc. · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11389481

    Allogeneic cell therapy of B cell malignancies using genetically engineered T cells targeting CD19

    CRISPR THERAPEUTICS AG · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11390921

    Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs)

    Adaptive Biotechnologies Corporation · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11390884

    Optimized CRISPR/cas9 systems and methods for gene editing in stem cells

    Editas Medicine, Inc. · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11390848

    Materials and methods for modifying the activity of T cells

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11390683

    Anti-mesothelin polypeptides and proteins

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11390667

    Compositions and methods for the treatment of neuromyelitis optica

    The Regents of the University of California · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11390631

    Benzodiazepine derivatives as RSV inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11389663

    Laser assisted wound healing protocol and system

    BIOREGENTECH, INC. · Granted Tue Jul 19 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 14 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2042?

1,738 published patents in our USPTO index have expiration dates falling in calendar year 2042.