Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2042

Annual patent cliff calendar for 2042 — US pharmaceutical patents by expiration date.

Patents
1,738

Quick answer

1,738 indexed pharmaceutical patents have expiration dates in 2042. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11371008

    Systems for producing cellular immunotherapeutics and methods of use thereof

    Northwestern University · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11370831

    Compositions and methods for treating and preventing Staphylococcus aureus infections

    XBIOTECH INC. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11370827

    Chimeric factor VIII polypeptides and uses thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11370825

    Polypeptides, cells, and methods involving engineered CD16

    Regents of the University of Minnesota · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11370821

    T-cell modulatory multimeric polypeptides and methods of use thereof

    Cue Biopharma, Inc. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11370803

    Heteroaryl plasma kallikrein inhibitors

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11370789

    Octahydro fused azadecalin glucocorticoid receptor modulators

    Corcept Therapeutics Incorporated · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11370787

    Pyrazole compounds, formulations thereof, and a method for using the compounds and/or formulations

    Rigel Pharmaceuticals, Inc. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11370786

    GLS1 inhibitors for treating disease

    The Board of Regents of the University of Texas System · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11370765

    RIP1 inhibitory compounds and methods for making and using the same

    Rigel Pharmaceuticals, Inc. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11370774

    Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors

    BioCryst Pharmaceuticals, Inc. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11369896

    Methods for quantitating individual antibodies from a mixture

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11369692

    Materials and methods for treatment of Duchenne Muscular Dystrophy

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11369716

    Reparative cell isolation and delivery

    The Board of Regents of the University of Texas System · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11369697

    Liposome nanoparticles for tumor magnetic resonance imaging

    United Kingdom Research and Innovation · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11369688

    Hybrid telodendrimers

    The Regents of the University of California · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11369683

    Systems and methods for targeted imaging and ablation of cardiac cells

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11369675

    Broadly protective inactivated influenza virus vaccine

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11370757

    Photocleavable nitroindoline-based crosslinkers

    The Board of Regents of the University of Texas System · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11369657

    Small molecule polypeptide for preventing and restraining inflammation and application of same

    SHANGHAI FIRST PEOPLE'S HOSPITAL · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. CA 3202908

    ANTAGONISTE D'INTEGRINES ALPHA-V BETA-3 ET/OU ALPHA-V BETA-5 RADIOMARQUE DESTINE A ETRE UTILISE EN TANT QU'AGENT THERAGNOSTIQUE

    ADVANCED ACCELERATOR APPLICATIONS INT SA [CH] · Granted Thu Jun 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 25 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11376273

    Modulation of factor 11 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11376247

    Tyrosine kinase inhibitors regenerate non-cancerous tissue after cancer therapy

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11377478

    T-cell modulatory multimeric polypeptides and methods of use thereof

    Cue Biopharma, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11377491

    Anti-leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) monoclonal antibodies and method of use thereof to treat cancer

    The Board of Regents of the University of Texas System · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11377428

    RIP1 inhibitory compounds and methods for making and using the same

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11377646

    Modified cells comprising CRISPR systems

    The Regents of the University of California · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11376346

    Extracellular matrix for treating pelvic floor disorders and skeletal muscle degeneration

    The Regents of the University of California · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11377660

    Chimeric antigen receptors targeting B-cell maturation antigen

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11376221

    Polymer particles for neutrophil injury

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11377468

    Antimicrobial compounds, compositions, and uses thereof

    Lakewood Amedex, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11377450

    Functionalized heterocycles as antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11376225

    Composite flash-precipitated nanoparticles

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11376214

    Compositions and methods for treatment of ocular diseases

    KIORA PHARMACEUTICALS GmbH · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11377659

    Short hairpin RNA (shRNA734) and use of same to positively select and eliminate genetically modified cells

    THE REGENTS OF THE UNIVERSITY OE CALIFORNIA · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11377502

    Anti-MSR1 antibodies and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11377643

    Therapeutics for glycogen storage disease type III

    Ultragenyx Pharmaceutical Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11377469

    CD73 inhibitors

    ORIC PHARMACEUTICALS, INC. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11376318

    Methods of preparing anti-human papillomavirus antigen t cells

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11377447

    Targeted therapeutics

    Madrigal Pharmaceuticals, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11377444

    Pyridopyrimidine compounds acting as mTORC 1/2 dual inhibitors

    Medshine Discovery Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11377451

    Compositions and methods for treating cancer

    The Regents of the University of California · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11376324

    Sting activating nanovaccine for immunotherapy

    The Board of Regents of the University of Texas System · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11377421

    Psychotropic agents and uses thereof

    LB PHARMACEUTICALS INC. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11376405

    Therapeutic agent preparations into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11376404

    Drug releasing coatings for medical devices

    Lutonix, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11376313

    Cancer treatment

    Propanc Pty Ltd · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11376263

    Cyproterone acetate compositions and uses thereof

    Fortress Biotech, Inc. · Granted Tue Jul 05 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 30 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2042?

1,738 published patents in our USPTO index have expiration dates falling in calendar year 2042.