Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2042

Annual patent cliff calendar for 2042 — US pharmaceutical patents by expiration date.

Patents
1,738

Quick answer

1,738 indexed pharmaceutical patents have expiration dates in 2042. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11365413

    Inhibition of poly(A) binding protein and the treatment of pain

    The Board of Regents of the University of Texas System · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11365394

    Enhanced immune effector cells and use thereof

    Fate Therapeutics, Inc. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11365416

    Modulators of EZH2 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11365293

    Xylan-based dual network nanocomposite hydrogel, preparation method thereof and use therefor

    South China University of Technology · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11365280

    Photocurable resin composition

    KURARAY NORITAKE DENTAL INC. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11365262

    Cell

    AUTOLUS LIMITED · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11365250

    Compositions and methods for cancer therapy

    The Board of Regents of the University of Texas System · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11365246

    Anti CCL24 (EOTAXIN2) antibodies for use in the treatment of hepatic diseases

    CHEMOMAB LTD. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11365230

    Compositions comprising lentiviral vectors expressing IL-12 and methods of use thereof

    IMMUNE DESIGN CORP. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11365205

    Imidazolidin-2-one compounds as PRMT5 modulators

    Aurigene Discovery Technologies Limited · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11365195

    Atypical inhibitors of monoamine transporters; method of making; and use thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11365221

    Compositions and methods for treating autoimmune and inflammatory disorders

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11364308

    Adeno-associated virus variant capsids and methods of use thereof

    4D MOLECULAR THERAPEUTICS INC. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11364300

    C40-, C28-, and C-32-linked rapamycin analogs as mTOR inhibitors

    Revolution Medicines, Inc. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11364304

    Crosslinked micellar spherical nucleic acids

    Northwestern University · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11364309

    Neuronal enhancers

    UNIVERSITY OF CONNECTICUT · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11365183

    Eicosanoid derivatives

    The Board of Regents of the University of Texas System · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11364293

    Compositions and methods for making and using thermostable immunogenic formulations with increased compatibility of use as vaccines against one or more pathogens

    The Regents of the University of Colorado · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11364261

    Alleviating common cold and influenza symptoms with molecular hydrogen

    H2 Universe LLC · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11364260

    Methods and compositions for administration of iron

    American Regent, Inc. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11364228

    Gaboxadol for therapeutic treatment of 1p36 deletion syndrome

    OVID THERAPEUTICS INC. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11364227

    Sphingosine kinase 2 inhibitor for treating coronavirus infection

    RedHill Biopharma Ltd. · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11364215

    GHB formulation and method for its manufacture

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 16 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. CA 3201259

    MASITINIB POUR LE TRAITEMENT DE LA MALADIE D'ALZHEIMER

    AB SCIENCE [FR] · Granted Thu Jun 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. WO 2022131944

    RÉGIMES DE TRAITEMENT DE LA MALADIE DE PARKINSON IDIOPATHIQUE PRÉCOCE

    BIAL PORTELA & CA SA [PT] · Granted Thu Jun 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 2022193051

    TREATMENT OF MIGRAINE

    ALLERGAN PHARMACEUTICALS INTERNTIONAL LTD [IE] · Granted Thu Jun 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11369684

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11370808

    Pyrazole compounds and methods for making and using the compounds

    Rigel Pharmaceuticals, Inc. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11369689

    Muscle targeting complexes and uses thereof for treating dystrophinopathies

    Dyne Therapeutics, Inc. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11369637

    Restimulation of cryopreserved tumor infiltrating lymphocytes

    Iovance Biotherapeutics, Inc. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11369566

    Controlled release antimicrobial compositions and methods for the treatment of otic disorders

    The Regents of the University of California · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11369627

    Myrtle polysaccharide P1, the separation method thereof and the use in preparing hypolipidemic drugs therefor

    South China Normal University School of Life Sciences · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11369674

    Treatment method utilizing chikungunya virus (CHIKV) virus-like particles (VLPS) comprising the C, E2 and E1 structural proteins

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11369588

    NADPH production by the 10-formyl-THF pathway, and its use in the diagnosis and treatment of disease

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11369575

    PPARα agonist compositions and methods of use

    The Board of Regents of the University of Oklahoma · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11369644

    Microbial consortia

    The Regents of the University of California · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11369622

    Methods and compounds to inhibit enveloped virus release

    Northwestern University · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11372008

    Blood factor monitoring assay and uses thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11370769

    TRPC5 inhibitors and methods of using same

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11371062

    RNA-guided nucleic acid modifying enzymes and methods of use thereof

    The Regents of the University of California · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11372002

    Assays for determining plasma kallikrein system biomarkers

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11370843

    High affinity antibodies to human IL-6 receptor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11370836

    Monoclonal antibody binding to human IL-5, preparation method therefor and use thereof

    SUNSHINE GUOJIAN PHARMACEUTICAL (SHANGHAI) CO., LTD. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11370832

    Anti-Tau antibodies and methods of use thereof

    DENALI THERAPEUTICS INC. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11371024

    Attenuation of human respiratory syncytial virus by genome scale codon-pair deoptimization

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11371008

    Systems for producing cellular immunotherapeutics and methods of use thereof

    Northwestern University · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11370831

    Compositions and methods for treating and preventing Staphylococcus aureus infections

    XBIOTECH INC. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11370827

    Chimeric factor VIII polypeptides and uses thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Jun 28 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 23 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2042?

1,738 published patents in our USPTO index have expiration dates falling in calendar year 2042.