Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2042

Annual patent cliff calendar for 2042 — US pharmaceutical patents by expiration date.

Patents
1,738

Quick answer

1,738 indexed pharmaceutical patents have expiration dates in 2042. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11317968

    Methods and compositions for tissue adhesives

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11318133

    Modulators of integrated stress response pathway

    PRAXIS BIOTECH LLC · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11319290

    Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same

    Mebias Discovery, Inc. · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11318186

    Use of FGF21 in methods of increasing exocrine pancreatic secretion

    The Board of Regents of the University of Texas System · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11318190

    Methods and compositions for treating liver disease

    United States Government as represented by the Department of Veterans Affairs · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11318205

    IRAK degraders and uses thereof

    Kymera Therapeutics, Inc. · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11319298

    Heteroaryl piperidine ether allosteric modulators of the M4 muscarinic acetylcholine receptor

    MSD R&D (China) Co. Ltd. · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11319302

    PRC1 inhibitors and methods of treatment therewith

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11318211

    Dosage regimes for the administration of an anti-CD19 ADC

    ADC THERAPEUTICS SA · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11318164

    Immunotherapeutic treatment method using an interleukin-2 receptor beta-selective agonist in combination with adoptive cell transfer therapy

    Nektar Therapeutics · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11318091

    Gastroretentive dosage forms for sustained drug delivery

    Amneal Complex Products Research LLC · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11318224

    Nanofiber structures and methods of use thereof

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue May 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 28 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11324734

    Compositions and methods for treating anemia

    Akebia Therapeutics, Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11325907

    Crystal form of 1H-imidazo[4,5-b]pyridine-2(3H)-one compound and preparation process therefor

    Medshine Discovery Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11324753

    Method of treatment of attention deficit/hyperactivity disorder (ADHD)

    Supernus Pharmaceuticals, Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11325957

    Methods and compositions for reducing the immunogenicity of chimeric notch receptors

    Cell Design Labs, Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11325925

    Dihydropyridazine antioxidant sunscreens

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11324760

    Solid dispersion of dutasteride, method for preparing the solid dispersion, and pharmaceutical composition including the solid dispersion

    KOREA PRIME PHARM CO., LTD. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11324811

    Optimization of enzyme replacement therapy for treatment of homocystinuria

    The Regents of the University of Colorado, a Body Corporate · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11324673

    Cosmetic appearance of skin

    MIRAKI INNOVATION THINK TANK LLC · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11324735

    Method of treatment with tradipitant

    VANDA PHARMACEUTICALS INC. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11324725

    Compositions and methods for the inhibition of pruritus

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11326156

    Modified caspase-9 polypeptides and methods of use thereof

    Allogene Therapeutics, Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11325978

    Compositions and methods for treating beta-globinopathies

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11324813

    Indoleamine 2,3-dioxygenase based immunotherapy

    IO Biotech ApS · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11325938

    CD73 inhibitors

    ORIC PHARMACEUTICALS, INC. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11325965

    Single-domain VH H antibodies directed to norovirus GI.1 and GII.4 and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11326166

    Xanthine dehydrogenase (XDH) iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11325936

    Sialidase inhibitors and preparation thereof

    The Regents of the University of California · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11326182

    Compositions for the treatment of disease

    VOYAGER THERAPEUTICS, INC. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11324935

    Implants for localized drug delivery and methods of use thereof

    The Regents of the University of California · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11327083

    Treatment and differential diagnosis of Cushing's disease and ectopic Cushing's syndrome

    Corcept Therapeutics Incorporated · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11325973

    Modulation of stimulatory and non-stimulatory myeloid cells

    The Regents of the University of California · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11325916

    Spiropyrrolidine derived antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11324820

    Methods for the treatment of subjects having a hepatitis b virus (HBV) infection

    Alnylam Pharmaceuticals, Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11325898

    Small molecule inducers of autophagy

    The Board of Regents of the University of Texas System · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11325902

    Benzenesulfonamide compounds and their use as therapeutic agents

    Xenon Pharmaceuticals Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11324822

    Combination of HDAC inhibitor and anti-PD-1 antibody for treatment of cancer

    Syndax Pharmaceuticals, Inc. · Granted Tue May 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. AU 2020370603

    Chikungunya virus-like particle vaccine and methods of using the same

    BAVARIAN NORDIC AS [DK] · Granted Thu May 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 07 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11331286

    Inhibitors and their uses

    United Kingdom Research and Innovation · Granted Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11332721

    Recombinant respiratory syncytial virus strains with mutations in the M2-2 ORF providing a range of attenuation phenotypes

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11332470

    CXCR4 inhibitors and uses thereof

    X4 Pharmaceuticals, Inc. · Granted Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11331395

    Hydrogel prodrug for treatment

    Viking Scientific, Inc. · Granted Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11331370

    Combination product for the prevention of sexually transmitted infections

    The United States of America · Granted Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11331363

    Phytocomplexes exhibiting multiple, synergistic antioxidant activities useful in foods, dietary supplements, cosmetics and pharmaceutical preparations

    Nature's Sunshine Products, Inc. · Granted Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11331333

    Treatment of aberrant fibroblast proliferation

    The Board of Regents of the University of Texas System · Granted Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11331285

    Dosage forms and methods for enantiomerically enriched or pure bupropion

    AXSOME THERAPEUTICS, INC. · Granted Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11331365

    Multispecific protein drug and library thereof, preparing method therefor and application thereof

    Assembly Medicine, LLC · Granted Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2042?

1,738 published patents in our USPTO index have expiration dates falling in calendar year 2042.