Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11168325

    Methods for treatment of polycystic kidney disease

    The Board of Regents of the University of Texas System · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11169142

    Viscoelastic analysis in patients with disease associated with cardiovascular system

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11168316

    Chimeric clotting factors

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11166976

    S-antigen transport inhibiting oligonucleotide polymers and methods

    Aligos Therapeutics, Inc. · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11166990

    Methods and compositions for treating ulcerative colitis

    Finch Therapeutics Holdings LLC · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11166936

    Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity

    Auransa Inc. · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11166942

    Inhibitors of integrated stress response pathway

    PRAXIS BIOTECH LLC · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11166964

    Treatment for modulating gut microbiota

    GALMED RESEARCH AND DEVELOPMENT LTD · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11167025

    Altering the immundominance hierarchy using a DNA vaccine expressing conserved regions

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11168125

    Immunoglobulin chimeric monomer-dimer hybrids

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11168303

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11168102

    Bicyclic heteroaryl compounds and uses thereof

    Revolution Medicines, Inc. · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11166937

    Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders

    Amazentis SA · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. BR 112021015776

    Edição de gene para hemofilia a com expressão de fator viii melhorada

    BAYER HEALTHCARE LLC [US] · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11166906

    Programmable pharmaceutical compositions for chrono drug release

    Amneal Complex Products Research LLC · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11166929

    Fatty-acid based particles

    ATRIUM MEDICAL CORPORATION · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11166924

    N-methyl-d-aspartate receptor allosteric modulators and methods for their use

    Qingdao Primedicine Pharmaceutical Company, Ltd. · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11166963

    Natural combination hormone replacement formulations and therapies

    Compass Therapeutics LLC · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11166962

    Methods and compositions comprising ursolic acid and/or resveratrol for treating diabetes, or cancer

    The Board of Regents of the University of Texas System · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11166960

    Modified release preparations containing oxcarbazepine and derivatives thereof

    Supernus Pharmaceuticals, Inc. · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11166949

    NURR1 activation in the treatment of metabolic disorders and as an exercise mimetic

    The Board of Regents of the University of Texas System · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11166957

    Antiviral prodrugs and nanoformulations thereof

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Nov 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. EP 3906927

    VERWENDUNG VON DOPAMIN-D3-TEILAGONISTEN ZUR BEHANDLUNG VON STÖRUNGEN DES ZENTRALEN NERVENSYSTEMS

    BIOPROJET PHARMA [FR] · Granted Wed Nov 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Nov 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11174292

    Substitutions-modified prefusion RSV F proteins and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11174316

    Anti-PDL1 antibodies, activatable anti-PDL1 antibodies, and methods of use thereof

    CytomX Therapeutics, Inc. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11174495

    Reporter system for detecting and targeting activated cells

    The Board of Regents of the University of Texas System · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11174486

    Engineered bacteria for production and release of therapeutics

    The Regents of the University of California · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11174481

    Targeting ligands

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11174514

    Methods, kits, and devices utilizing HTR2C polymorphisms for diagnosing, prognosing, and treating psychiatric disorders in a patient

    Northwestern University · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11174320

    HER3 specific monoclonal antibodies for diagnostic and therapeutic use

    The Board of Regents of the University of Texas System · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11174305

    Human antibodies to Fel d1 and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11174469

    Materials and methods for treatment of Amyotrophic Lateral Sclerosis (ALS) and other related disorders

    CRISPR THERAPEUTICS AG · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11174301

    Peptide compound

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11174288

    Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

    Northwestern University · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11173207

    Adjuvant compositions

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11173201

    Methods and compositions for inducing protective immunity against filovirus infection

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11173165

    Optimizing mifepristone levels for Cushing's patients

    Corcept Therapeutics Incorporated · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11173161

    4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11173159

    Methods and compositions for inhibition of polymerase

    BioCryst Pharmaceuticals, Inc. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11173150

    Method for diagnosing, preventing, and treating neurological diseases

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11173147

    Prophylactic or therapeutic agent for delirium

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11173145

    Compounds useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase

    The Board of Regents of the University of Texas System · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11174267

    Spiroindolinones and therapeutic uses thereof

    The Regents of the University of California · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11174262

    Compounds, compositions and methods

    DENALI THERAPEUTICS INC. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11174251

    Compositions and methods for inhibition of the JAK pathway

    Rigel Pharmaceuticals, Inc. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11174268

    Benzenesulfonamide compouds and their use as therapeutic agents

    Xenon Pharmaceuticals Inc. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11174283

    Anti-VEGF protein compositions and methods for producing the same

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11174246

    Direct AMPK activators

    Rigel Pharmaceuticals, Inc. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.