Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11147801

    Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors

    Aurigene Discovery Technologies Limited · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11147795

    Neuroprotective compounds and methods of use

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11147782

    GHB formulation and method for its manufacture

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11147773

    Chloroquine gel and preparation method and application thereof

    GUANGZHOU HYBRIBIO BIOTECH LTD. · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11147784

    Dietary supplements and composition for treating cancer

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11147790

    Treatment of cutaneous disorders

    Verrica Pharmaceuticals Inc. · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11147631

    System and method of performing treatment along a lumen network

    Covidien LP · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11150237

    Patient-specific biomarkers of Escherichia coli invasion in inflammatory bowel disease

    The Regents of the University of California · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11149273

    Lipid formulated compositions and methods for inhibiting expression of serum amyloid A gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11147946

    Venous access catheters and methods for portal venous system catheterization

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11149020

    MAP kinase modulators and uses thereof

    Northwestern University · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11147746

    Hydrophobic dental surfaces

    Regents of the University of Minnesota · Granted Tue Oct 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. CA 3175580

    AGENTS IMMUNOSTIMULATEURS EN COMBINAISON AVEC DES INHIBITEURS DE L'ANGIOGENESE

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu Oct 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. CA 3175356

    AGENTS IMMUNOSTIMULATEURS EN COMBINAISON AVEC DES INHIBITEURS DE L'ANGIOGENESE

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu Oct 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11156612

    Methods of determining levels of cleaved and/or intact kininogen

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11155567

    Sting agonist compounds and methods of use

    Mersana Therapeutics, Inc. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11155549

    Ester and carbonate pyrimidine compounds as JAK kinase inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11155525

    Azole derivatives as apelin receptor agonist

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11155523

    Biphenyl compound as CCR2/CCR5 receptor antagonist

    Medshine Discovery Inc. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11154639

    Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same

    The Regents of the University of California · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11155547

    Compounds for and methods of treating diseases

    Alterity Therapeutics Limited · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11155533

    Crystalline forms and compositions of CFTR modulators

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11154606

    Vaccine for prevention of necrotic enteritis in poultry

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11154601

    Cancer vaccines targeting BORIS and uses thereof

    Inovio Pharmaceuticals, Inc. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11155834

    Sin Nombre virus full-length M segment-based DNA vaccines

    The Government of the United States, as represented by the Secretary of the Army · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11155804

    Recombinant polypeptides comprising selenocysteine and method for producing the same

    The Board of Regents of the University of Texas System · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11155821

    Compositions and methods for tagging ribonucleic acids

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11155803

    Adenosine deaminase base editors and methods of using same to modify a nucleobase in a target sequence

    Beam Therapeutics Inc. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11155815

    Compositions and methods for modulating Tau expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11155621

    Anti-CD3 antibodies, bispecific antigen-binding molecules that bind CD3 and CD20, and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11155598

    GPR156 variants and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11155633

    Anti-PSMA antibodies, bispecific antigen-binding molecules that bind PSMA and CD3, and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11155599

    Adenoviruses expressing heterologous tumor-associated antigens

    The Board of Regents of the University of Texas System · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11155559

    Sulfonyl-substituted isoquinolines as inhibitors of RHO kinase and hERG potassium channel activity

    CHINA RESOURCES PHARMACEUTICAL HOLDINGS COMPANY LIMITED · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11154636

    Antimicrobial biopolymer compositions, methods of synthesis, and applications of use

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11154602

    Cancer vaccines targeting mesothelin and uses thereof

    Inovio Pharmaceuticals, Inc. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11154574

    Tumor infiltrating lymphocytes and methods of therapy

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11154572

    Methods of treatment with natural killer cells matched for killer immunoglobulin receptor type

    The Board of Regents of the University of Texas System · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11154500

    Solid solution compositions and use in chronic inflammation

    Infirst Healthcare Limited · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11154614

    Method for producing virus like particles

    INTEGRATED RESEARCH ASSOCIATES, LLC · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11154608

    Dengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes

    The Government of the United States of America as represented by the Secretary of the Deptartment of Health and Human Services · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11155563

    Macrocyclic compounds and uses thereof

    TURNING POINT THERAPEUTICS, INC. · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11154573

    Methods of generating T-cells from stem cells and immunotherapeutic methods using the T-cells

    The Regents of the University of California · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11154557

    Antiviral prodrugs and nanoformulations thereof

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11154556

    Methods of treating solid tumors with CCR2 antagonists

    The Regents of the University of California · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11155879

    Method of predicting effects of CDC7 inhibitor

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11154519

    Inhibitors and their uses

    United Kingdom Research and Innovation · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11154494

    Programmable pharmaceutical compositions for chrono drug release

    Amneal Complex Products Research LLC · Granted Tue Oct 26 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 21 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.