Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11117972

    Multivalent and multispecific OX40-binding fusion proteins

    Inhibrx, Inc. · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11116838

    Checkpoint inhibitor and vaccine combinations and use of same for immunotherapy

    Inovio Pharmaceuticals, Inc. · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11116830

    Bacterial polysaccharide-conjugated carrier proteins and use thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11116823

    Treatment of α-galactosidase a deficiency

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11116797

    Universal donor cells

    CRISPR THERAPEUTICS AG · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11116740

    Methods for use in support of planned supplement and food ingredient products for diagnosis and treatment of metabolic syndrome

    United States of America as represented by the Secretary of the Air Force · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11116733

    Topical dapsone and dapsone/adaplene compositions and methods for use thereof

    ALMIRALL, LLC · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11116717

    Soluble estradiol capsule for vaginal insertion

    Compass Therapeutics LLC · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11116214

    Lice control composition and method

    TYRATECH, INC. · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11116798

    Universal donor cells

    CRISPR THERAPEUTICS AG · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11116825

    Cancer vaccine compositions and methods of using the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11117865

    Inhibitors of bromodomain-containing protein 4 (BRD4)

    The Board of Regents of the University of Texas System · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11117945

    T-cell modulatory multimeric polypeptides and methods of use thereof

    Cue Biopharma, Inc. · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11117867

    Crystalline salts of a plasma kallikrein inhibitor

    BioCryst Pharmaceuticals, Inc. · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11117934

    Oncolytic virus platform to treat cancers with myxoma virus

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11116839

    Methods for reducing lipoprotein(a) levels by administering an inhibitor of proprotein convertase subtilisin kexin-9 (PCSK9)

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11116843

    Conjugated antisense compounds and their use

    Ionis Pharmaceuticals, Inc. · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11117904

    Compositions and methods for the delivery of therapeutics

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11117900

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. CA 3174918

    OPICAPONE MICRONISEE

    BIAL PORTELA & CA SA [PT] · Granted Thu Sep 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. WO 2021182981

    OPICAPONE MICRONISÉE

    BIAL PORTELA & Cª S A [PT] · Granted Thu Sep 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11123286

    Auris formulations for treating otic diseases and conditions

    The Regents of the University of California · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11125741

    Compositions and methods for the detection of zinc

    Northwestern University · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11123441

    Methods and compositions for drug delivery

    The Regents of the University of California · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11124835

    Methods of diagnosing chronic obstructive pulmonary disease (COPD) using novel molecular biomarkers

    Transgenion—International Institute for Regenerative Translational Medicine GmbH · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11124545

    Foot and mouth disease virus (FMDV) consensus proteins, coding sequences therefor and vaccines made therefrom

    Inovio Pharmaceuticals, Inc. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11124541

    Chimeric melanocortin ligands and methods of use thereof

    Regents of the University of Minnesota · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11124537

    Inhibitors of glucocorticoid receptor

    ORIC PHARMACEUTICALS, INC. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11124489

    EPAC antagonists

    The Board of Regents of the University of Texas System · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11123371

    Restimulation of cryopreserved tumor infiltrating lymphocytes

    Iovance Biotherapeutics, Inc. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11123312

    Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects

    The Regents of the University of California · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11123285

    Auris formulations for treating OTIC diseases and conditions

    The Regents of the University of California · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11122832

    Methods and compositions to improve weight loss and cardiometabolic health beyond diet and excercise

    Nature's Sunshine Products, Inc. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11123283

    Soluble estradiol capsule for vaginal insertion

    Compass Therapeutics LLC · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11123311

    Methods of treating mental disorders

    The Regents of the University of California · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11123295

    Encholeated antifungal compounds for central nervous system delivery and treatment of Cryptococcus infections

    MATINAS BIOPHARMA NANOTECHNOLOGIES, INC. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11124839

    Methods of treating cancer patients with farnesyltransferase inhibitors

    Kura Oncology, Inc. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11123302

    Formulation of acoustically activatable particles having low vaporization energy and methods for using same

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11123344

    Bupropion as a modulator of drug activity

    AXSOME THERAPEUTICS, INC. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11123340

    Small-molecule UT-A-selective urea transport inhibitors

    The Regents of the University of California · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11123357

    Methods and compositions for treating oral mucositis

    Lakewood Amedex, Inc. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11123360

    Oligonucleotides to treat eye disease

    ProQR Therapeutics II B.V. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11123334

    Compositions and methods for treating opioid overdose and opioid abuse

    The Board of Regents of the University of Texas System · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11123351

    Pharmaceutical formulation of 3-alpha-ethynyl-3-beta-hydroxyandrostan-17-one oxime

    Umecrine Cognition AB · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11123399

    Modulators of complement activity

    RA PHARMACEUTICALS, INC. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11123443

    Htt repressors and uses thereof

    Sangamo Therapeutics, Inc. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11123431

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11123377

    Compositions for fecal floral transplantation and methods for making and using them and device for delivering them

    Finch Therapeutics Holdings LLC · Granted Tue Sep 21 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 16 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.