Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11078245

    Colon and pancreas cancer peptidomimetics

    PRECISION BIOLOGICS, INC. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11078190

    Polymorphs of selinexor

    Karyopharm Therapeutics Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11077241

    Standardizations and medical devices for the preparation of platelet rich plasma (PRP) or bone marrow concentrate (BMC) alone or in combination with hyaluronic acid

    RegenLab USA LLC · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11077182

    Methods of preparing anti-human papillomavirus antigen T cells

    THE UNITED STATES OF AMERICA, represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11078168

    Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase

    Phenex Discovery Verwaltungs-GmbH · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11077200

    Combined enteropathogen recombinant construct

    United States of America as represented by the Secretary of the Air Force · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11077197

    Lipids and compositions for the delivery of therapeutics

    ARBUTUS BIOPHARMA CORPORATION · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11077175

    Compositions and methods for treatment of homocystinuria

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11077123

    Use of bile acids and bile salts as anti bacterial agents for inhibition of bacterial conjugation and horizontal gene transfer

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11077114

    Stabilized formulations of CNS compounds

    Supernus Pharmaceuticals, Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11077117

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11077108

    Allosteric corticotropin-releasing factor receptor 1 (CRFR1) antagonists that decrease p-tau and improve cognition

    The Regents of the University of California · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11077079

    GHB formulation and method for its manufacture

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11077078

    Compositions and methods for the treatment of cancer

    KoDiscovery, LLC · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11078170

    Cyclic sulfamide compounds and methods of using same

    ASSEMBLY BIOSCIENCES, INC. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11077101

    Compounds and methods of use

    Tango Therapeutics, Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11077090

    Compounds and compositions and uses thereof

    PGI Drug Discovery LLC · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11077072

    Binge behavior regulators

    CLEARMIND MEDICINE INC. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11077068

    Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions

    Aquestive Therapeutics, Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11076599

    Antimicrobial coating comprising chalcogenide nano-particles capped by chitosan

    The Board of Regents of the University of Texas System · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11077057

    Polymer-grafted nanobins

    Northwestern University · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11078205

    Selective inhibitors of protein arginine methlytransferase 5 (PRMT5)

    Prelude Therapeutics, Incorporated · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11078227

    5′-cyclo-phosphonate modified nucleotides

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. WO 2021152186

    ANTICORPS CCR8 POUR APPLICATIONS THÉRAPEUTIQUES

    BAYER AG [DE] · Granted Thu Aug 05 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jul 31 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11084865

    VEGF antagonist formulations suitable for intravitreal administration

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11084809

    N-((HET)arylmethyl)-heteroaryl-carboxamides compounds as kallikrein inhibitors

    KalVista Pharmaceuticals Limited · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11086049

    Anti-microbial bandage contact lens with ocular drug delivery

    The Regents of the University of California · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11084869

    Antibody-mediated neutralization of Marburg virus

    The Board of Regents of the University of Texas System · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11083720

    Indazole inhibitors of fructokinase (KHK) and methods of use in treating KHK-mediated disorders or diseases

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11084856

    Interleukin-4 receptor-binding fusion proteins and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11084844

    Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom

    Ionis Pharmaceuticals, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11083736

    Compositions comprising triterpenoids

    REGENERA PHARMA LTD. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11083752

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11083758

    Placental membrane preparations and methods of making and using same for regenerating cartilage and spinal intervertebral discs

    Prime Merger Sub, LLC · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11083799

    Materials and methods for treatment of hereditary haemochromatosis

    CRISPR THERAPEUTICS AG · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11083801

    Factor VIII mutation repair and tolerance induction

    The United States Government Represented by the Departrment of Veteran Affairs · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11084798

    2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors

    IDEAYA Biosciences, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11084884

    Plasma kallikrein binding proteins and uses thereof in treating hereditary angioedema

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11085057

    Compositions and methods for modifying a target nucleic acid

    The Regents of the University of California · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11084859

    Targeted mutant interferon-gamma and uses thereof

    Orionis Biosciences, Inc · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11085022

    Inflammation-targeted neutrophil granulocyte drug delivery system and use thereof

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11084842

    Glucopyranosyl derivative and use thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11084872

    Method for treating breast cancer

    ADC THERAPEUTICS SA · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11083696

    Dispersion anaesthetic device

    University College Cardiff Consultants Limited · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11083635

    Tampon delivery system for a pharmaceutical, holistic or medicinal component

    Herphoric, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11083708

    Pharmacological restoration of epithelial or endothelial barrier integrity by agents blocking EPAC/RAP1 signaling

    The Regents of the University of California · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11083737

    Methods of administering deflazacort therapy

    PTC THERAPEUTICS, INC. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11083745

    Antisense oligomers for treatment of autosomal dominant mental retardation-5 and Dravet Syndrome

    STOKE THERAPEUTICS, INC. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.