Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11033491

    Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof

    Vyne Therapeutics Inc. · Granted Tue Jun 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11034956

    Oligonucleotide comprising an inosine for treating DMD

    BIOMARIN TECHNOLOGIES B.V. · Granted Tue Jun 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11035859

    Compositions and methods for detecting protease activity in biological systems

    CytomX Therapeutics, Inc. · Granted Tue Jun 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11034933

    Methods for selectively expanding and enriching cells transduced with chimeric antigen receptors and treating HIV infection

    The Regents of the University of California · Granted Tue Jun 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11034750

    Chimeric antigen receptor (CAR) comprising a CD19-binding domain

    AUTOLUS LIMITED · Granted Tue Jun 15 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 10 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. CN 112996764

    CHELATING AAZTA CONJUGATES AND COMPLEXES THEREOF

    BRACCO IMAGING SPA · Granted Fri Jun 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Jun 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11040107

    Dosing regimens and related compositions and methods

    Apellis Pharmaceuticals, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11040970

    VMAT2 inhibitor compounds and compositions thereof

    Neurocrine Biosciences, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11040011

    Zinc meloxicam complex microparticle multivesicular liposome formulations and processes for making the same

    Pacira Pharmaceuticals, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11040019

    Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11040125

    Neurotrophic factor carrier, method for producing the same, and method for regenerating a nerve using the same

    Wiregene Co., Ltd. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11040935

    Small molecule AMPK activators

    THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11040965

    Process for making Hepatitis B core protein modulators

    ASSEMBLY BIOSCIENCES, INC. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11040943

    Psychotropic agents and uses thereof

    LB PHARMACEUTICALS INC. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11041008

    Heterodimers of IL-15 and IL-15R alpha to increase thymic output and to treat lymphopenia

    The Government of the United States of America as represented by the Secretary of the Deptartment of Health and Human Services · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11040027

    Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death

    HEPAREGENIX GMBH · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11040073

    Compositions and methods for treating diverticulitis and related disorders

    Finch Therapeutics Holdings LLC · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11040028

    Penicinotam derivative, preparation method and use thereof

    OCEAN UNIVERSITY OF CHINA · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11040036

    Pyruvate kinase activators for use in treating blood disorders

    Agios Pharmaceuticals, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11040082

    Compositions and methods for treating colorectal cancer

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11040090

    Botulinum neurotoxin compositions

    Prime Bio, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11040091

    Cycle adenosine monophosphate-incompetent adenylyl cyclase and compositions and methods for treating heart failure and increasing cardiac function

    The Regents of the University of California · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11040097

    Method of conferring a protective immune response to norovirus

    Takeda Vaccines, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11040040

    Methods of treating cancer

    Corvus Pharmaceuticals, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11040088

    Delivery of therapeutic compounds to the brain and other tissues

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11041174

    Compositions for linking DNA-binding domains and cleavage domains

    Sangamo Therapeutics, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11041000

    Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases

    Protagonist Therapeutics, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11040055

    Method of treating diabetic retinopathy or wet type adult macular degeneration

    China Medical University · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11040959

    Diprovocims: a new and potent class of TLR agonists

    The Board of Regents of the University of Texas System · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11040984

    Quinazoline compound for EGFR inhibition

    Medshine Discovery Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11041023

    Chimeric antigen receptors for phagocytosis

    The Regents of the University of California · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11041149

    PH20 polypeptide variants, formulations and uses thereof

    HALOZYME, INC. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11040039

    Treatment of inflammatory disorders

    Aldeyra Therapeutics, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11040109

    Blood coagulation protein conjugates

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11041170

    Multivalent vaccines for rabies virus and coronaviruses

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11040115

    Method for the treatment of lysosomal storage diseases

    Sangamo Therapeutics, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11041205

    Molecular targets for ALS and related disorders

    Northwestern University · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11041202

    Method of identifying human compatible T cell receptors specific for an antigenic target

    Adaptive Biotechnologies Corporation · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11040998

    Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11040084

    Stable antibody-drug conjugate, preparation method therefor, and use thereof

    GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11040070

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11040029

    Methods for the administration of certain VMAT2 inhibitors

    Neurocrine Biosciences, Inc. · Granted Tue Jun 22 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 17 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 2021186075

    COMPOSITIONS COMPRISING BACTERIAL STRAINS FOR USE IN INCREASING THE BIOAVAILABILITY OF AMINO ACIDS DERIVED FROM PROTEINS, AND RELATED FOOD PRODUCT METHODS AND SYSTEMS

    SOFAR SPA [IT] · Granted Thu Jun 24 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 19 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. SG 11202104918P

    THERAPY FOR TREATING CANCER WITH AN INTRATUMORAL AND/OR INTRAVENOUS ADMINISTRATION OF A RECOMBINANT MVA ENCODING 4-1BBL (CD137L) AND/OR CD40L

    BAVARIAN NORDIC AS [DK] · Granted Tue Jun 29 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 24 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11046752

    Serpin fusion polypeptides and methods of use thereof

    Inhibrx, Inc. · Granted Tue Jun 29 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 24 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11046670

    Piperazinyl norbenzomorphan compounds and methods for using the same

    The Board of Regents of the University of Texas System · Granted Tue Jun 29 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 24 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11045493

    Synthetic melanin nanoparticles and uses thereof

    The Regents of the University of California · Granted Tue Jun 29 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 24 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11046755

    Antibody based reagents that specifically recognize toxic oligomeric forms of tau

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Jun 29 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 24 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.