Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11021481

    Substituted isoindolin-1-ones and 2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-ones as HPK1 antagonists

    Nimbus Saturn, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 11021535

    Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 11021497

    Compositions and methods for synthesis of phosphorylated molecules

    The Regents of the University of California · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 11021469

    Indoline sulfonamide inhibitors of DapE and NDM-1 and use of the same

    The Board of Regents of the University of Texas System · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 11021506

    Thiosaccharide mucolytic agents

    The Regents of the University of California · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 11021542

    Humanized BCMA antibody and BCMA-CAR-T cells

    Caribou Biosciences, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 11021545

    Multimodal cancer therapy comprising chimeric viral/nonviral nanoparticles and anticancer agents

    The Regents of the University of California · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 11021515

    Therapeutically active compounds and their methods of use

    Agios Pharmaceuticals, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 11021465

    DNA-PK inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 11020495

    Humanized low affinity FCγR mouse cells

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 11020686

    Methods for quantitating individual antibodies from a mixture

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 11020485

    Pharmaceutical formulation

    Semnur Pharmaceuticals, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 11020403

    Precipitation resistant small molecule drug formulations

    XERIS PHARMACEUTICALS, INC. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 11020365

    Mixture of fatty acids for use in the treatment of inflammatory pathologies

    AGAIN LIFE ITALIA SRL · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 11021523

    Cyanobacteriochromes active in the far-red to near-infrared

    The Regents of the University of California · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 11020373

    Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof

    Amazentis SA · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 11021710

    Compounds and methods for reducing FXI expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 11020383

    Methods for the treatment of cancer metastasis

    The Board of Regents of the University of Texas System · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 11021458

    Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors

    BioCryst Pharmaceuticals, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 11021517

    Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic delivery

    The Regents of the University of California · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 11020510

    Muscle cell patches and uses therefor

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 11020492

    Gene correction of SCID-related genes in hematopoietic stem and progenitor cells

    Sangamo Therapeutics, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 11021435

    Serotonin receptor-targeting compounds and methods

    Northwestern University · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 11021468

    TGF-ß inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 11021696

    Nuclease-mediated regulation of gene expression

    Sangamo Therapeutics, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 11020436

    Multipotent and immunocompatible stem cell concentrate

    REGENERA—MEDICINA VETERINÁRIA AVANÇADA LTDA. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 11020345

    Nanostraw devices and methods of fabricating and using the same

    The Regents of the University of California The Board of Trustees of the Leland Stanford Junior University Stanford · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 11021454

    Type of aryl benzofuran amidated derivative and medical use thereof

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 11021707

    Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA

    Phio Pharmaceuticals Corp. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 11019810

    Non-human animals having a humanized signal-regulatory protein gene

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 11020463

    Method of determining cellular protein homeostasis

    The Regents of the University of California · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 11020409

    Broad antiviral therapy with membrane modifying oxysterols

    The Regents of the University of California · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 11020459

    Factor VIII formulations

    UNIVERSITY OF CONNECTICUT · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 11020438

    Phospholipid compositions and their preparation

    AKER BIOMARINE ANTARCTIC AS · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 11020458

    Factor VIII polymer conjugates

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 11020417

    Methods and compounds for treatment of lymphocyte-related diseases and conditions

    Sarepta Therapeutics, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 11020483

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 11020326

    Hollow particles and cosmetic

    JGC Catalysts and Chemicals Ltd. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 11020391

    CRMP2 sumoylation inhibitors and uses thereof

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 11020402

    Use of reboxetine to treat narcolepsy

    AXSOME THERAPEUTICS, INC. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 11020461

    Methods and compositions for CNS delivery of arylsulfatase A

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 11020470

    Virus-like particles

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 11020479

    Method for production of solid water particles for homeopathy

    American Quantum Health Inc · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 11020488

    Pyrroloquinolin compounds and methods of using same

    The Regents of the University of California · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 11021424

    Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers

    PTC THERAPEUTICS, INC. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 11021449

    Substituted triazoles and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 11021576

    Polymeric stabilizing formulations

    Nano Precision Medical, Inc. · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 11021706

    Antisense antibacterial compounds and methods

    The Board of Regents of the University of Texas System · Granted Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.