Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9884916

    High affinity antibodies to human IL-6 receptor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9884807

    Neprilysin inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9884841

    Small molecule inhibitors of Mcl-1 and uses thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9885045

    Methods and compositions for modulating apolipoprotein (a) expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9885047

    Modulation of TMPRSS6 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9885051

    Regulated expression of antigen and/or regulated attenuation to enhance vaccine immunogenicity and/or safety

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9885026

    Modified cascade ribonucleoproteins and uses thereof

    Caribou Biosciences, Inc. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9884009

    Plant composition having moisturizing, anti-wrinkle, and anti-allergic efficacies, and preparation method thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9885042

    miR-92 inhibitors and uses thereof

    MIRAGEN THERAPEUTICS, INC. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 9884863

    STAT3 inhibitor

    The Board of Regents of the University of Texas System · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9884868

    TGF-beta inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9884114

    Methods of rational nicotine hapten design and uses thereof

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9884907

    Methods for treating headache using antagonist antibodies directed against calcitonin gene-related peptide

    TEVA PHARMACEUTICALS INTERNATIONAL GMBH · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9884100

    Lutzomyia longipalpis polypeptides and methods of use

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9884820

    Pro-neurogenic compounds

    The Board of Regents of the University of Texas System · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9884096

    Compositions and methods related to graft versus host disease and treatments thereof

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9884076

    Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy

    Capricor, Inc. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9884050

    Inhibition of crystal growth of roflumilast

    Arcutis, Inc. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9884097

    Fungal immunogens and related materials and methods

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9884070

    Selective high-affinity polydentate ligands and methods of making such

    The Regents of the University of California · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9884908

    Methods for treating headache using antagonist antibodies directed against calcitonin gene-related peptide

    TEVA PHARMACEUTICALS INTERNATIONAL GMBH · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9884104

    Live attenuated virus vaccines for la crosse virus and other bunyaviridae

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9884859

    Solid form of pyrazolopyridine compound

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9884072

    Methods and compositions for modulating apolipoprotein (a) expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9884875

    Heterocyclic compound and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9884866

    Immunomodulators and immunomodulator conjugates

    Regents of the University of Minnesota · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9885018

    High efficiency reprogramming of fibroblasts into cardiomyocytes

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Feb 06 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 01 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 2018036436

    ETHYLENEDIAMINETETRAACETIC ACID BIS(AMIDE) DERIVATIVES AND THEIR RESPECTIVE COMPLEXES WITH MN(II) ION FOR USE AS MRI CONTRAST AGENT

    BRACCO IMAGING SPA [IT] · Granted Thu Feb 08 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 03 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9889115

    Fitness assay and associated methods

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9889137

    Therapeutically active compounds and their methods of use

    Agios Pharmaceuticals, Inc. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 9889125

    Methods for treating heartburn, gastric bleeding or hemorrhage in patients receiving clopidogrel therapy

    Takeda Pharmaceuticals U.S.A., Inc. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 9889152

    Multiple PPI dosage form

    Takeda Pharmaceuticals U.S.A., Inc. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 9889070

    Curable composition

    KURARAY NORITAKE DENTAL INC. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 9889081

    Aldehyde dehydrogenase inhibitors as novel depigmenting agents

    The Board of Regents of the University of Texas System · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 9889072

    Porous silica particle, method for producing the same, and cleansing cosmetic containing the same

    JGC Catalysts and Chemicals Ltd. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 9889156

    Method for treating noise-induced hearing loss (NIHL)

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 9889092

    Low density lipoprotein nanocarriers for targeted delivery of omega-3 polyunsaturated fatty acids to cancer

    The Board of Regents of the University of Texas System · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 9889071

    Calcium sulfate-resin hybrid materials and methods of using and making the same

    The Regents of the University of California · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 9889161

    Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 9888673

    Genetically modified cells, tissues, and organs for treating disease

    Regents of the University of Minnesota · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 9889160

    Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 9890487

    Liquid-retaining sheet and facial mask

    KURARAY KURAFLEX CO., LTD. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9890379

    Treatment of genetic disorders associated with DNA repeat instability

    BIOMARIN TECHNOLOGIES B.V. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9890362

    Compositions, methods and uses for inducing viral growth

    Takeda Vaccines, Inc. · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9890369

    Cytolethal distending toxin subunit B conjugated or fused to Bacillus anthracis toxin lethal factor

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 9890221

    Cellulose ethers esterified with dicarboxylic acid

    Regents of the University of Minnesota · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9890216

    Antibodies with engineered IgG Fc domains

    The Board of Regents of the University of Texas System · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9890145

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.