Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10125131

    Selective HDAC3 inhibitors

    Regenacy Pharmaceuticals, Inc. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10125167

    Compositions and methods for treating MRSA infections and for sensitizing MRSA to beta-lactam antibiotics

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10123947

    Dental cement

    KURARAY NORITAKE DENTAL INC. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10123979

    Methods of treating developmental disorders with biguanides

    OVID THERAPEUTICS INC. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10125112

    Modulators of the relaxin receptor 1

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10123759

    Systems, compositions, and methods for local imaging and treatment of pain

    The Regents of the University of California · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10123974

    Sustained release formulation of a non-steroidal anti-inflammatory drug

    Pacira Pharmaceuticals, Inc. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10125102

    Human plasma kallikrein inhibitors

    BioCryst Pharmaceuticals, Inc. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10123989

    Method of lowering cholesterol

    Med-Life Discoveries LP · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10125098

    Therapeutic compounds and methods of use thereof

    Xenon Pharmaceuticals Inc. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10124043

    Mutant OPAA enzymes with increased catalytic efficiency on organophosphorus compound EA1356

    The United States of America as represented by the Secretary of the Army · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10125369

    PCSK9 iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10125139

    Pesticidally active polycyclic derivatives with sulfur substituted five-membered ring heterocycles

    SYNGENTA (CHINA) INVESTMENT CO. LTD. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10125134

    KRas G12C inhibitors

    Mirati Therapeutics, Inc. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10125145

    5-HT3 receptor antagonists

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10125171

    Cell-reactive, long-acting, or targeted compstatin analogs and uses thereof

    Apellis Pharmaceuticals, Inc. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10125172

    Conformationally stabilized RSV pre-fusion F proteins

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10125361

    Compositions and methods of nucleic acid-targeting nucleic acids

    Caribou Biosciences, Inc. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10125188

    Human antibodies to respiratory syncytial virus F protein and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10125193

    Chimeric antigen receptors and methods of making

    The Board of Regents of the University of Texas System · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10126309

    Method for the detection of an albumin isoform

    The Board of Regents of the University of Texas System · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10124109

    Method and device for treating allergic reactions and difficult-to-manage respiratory diseases

    Pharmaceutical Design, LLC · Granted Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 2018326059

    COMBINATION THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER

    GANYMED PHARMACEUTICALS AG [DE] · Granted Thu Nov 15 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 10 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10130607

    Methods of reducing blood lactate concentration

    Stokely-Van Camp, Inc. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10130621

    Analogs of pridopidine, their preparation and use

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10130623

    Tyrosine kinase inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10130671

    Chardonnay grape seed products for nonalcoholic fatty liver disease

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10130676

    Therapeutic peptides for cerebrovascular diseases

    Prime Bio-Drug Development Limited · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10130658

    Method of ex vivo enhancement of immune cell activity for cancer immunotherapy with a small molecule ablative compound

    Provectus Pharmatech, Inc. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10130659

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10130677

    Antimicrobial peptide and uses thereof

    ACADEMISCH MEDISCH CENTRUM · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10131880

    Pluripotent human adipose adult stem cells: isolation, characterization and clinical implications

    The Regents of the University of California · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10130705

    Vaccines with interleukin-33 as an adjuvant

    Inovio Pharmaceuticals, Inc. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10132810

    Method for assessing and predicting efficacy of breast cancer treatment with a long-acting topoisomerase I inhibitor

    Nektar Therapeutics · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10131907

    Glycoconjugates of RNA interference agents

    Alnylam Pharmaceuticals, Inc. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10135517

    Relay link HARQ operation

    BlackBerry Limited · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10131676

    Compounds, compositions and methods

    DENALI THERAPEUTICS INC. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10131701

    Human leucine zipper/trail recombinant polypeptides

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10130594

    Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10130618

    Pharmaceutical combinations of dabigatran and proton pump inhibitors

    SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETI · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10130642

    Neprilysin inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10130651

    RNAi Therapy for Hepatitis B Virus Infection

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10130700

    Polyvalent influenza virus-like particles (VLPS) and use as vaccines

    The United States of America, as represented by the Secretary, DHHS · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10131668

    Substituted imidazo[1,5-a]pYRAZINES for modulation of IRE1

    The Regents of the University of California · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10131653

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10130723

    TCO conjugates and methods for delivery of therapeutic agents

    The Regents of the University of California · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10131659

    Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulations thereof; and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10130701

    Coronavirus

    The Pirbright Institute · Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.