Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10106581

    Cyclic peptidomimetic compounds as immunomodulators

    Aurigene Discovery Technologies Limited · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10106650

    Reversibly crosslinked micelle systems

    The Regents of the University of California · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10105341

    Treatment for obesity

    Jazz Pharmaceuticals International III Limited · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10105366

    Selective calcium channel antagonists

    Northwestern University · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10105354

    Inhibition of crystal growth of roflumilast

    Arcutis, Inc. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10106792

    Methods and compositions for the specific inhibition of gene expression by double-stranded RNA

    INTEGRATED DNA TECHNOLOGIES, INC. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10105344

    Methods of reducing blood lactate concentration

    Stokely-Van Camp, Inc. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10105369

    Therapeutically active compounds and their methods of use

    Agios Pharmaceuticals, Inc. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10105376

    Omega-3 compositions

    AKER BIOMARINE ANTARCTIC AS · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10105289

    Biomimetic mineral based endodontic cement composition and uses thereof

    Essential Dental Systems, Inc. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10106796

    Compound and method for treating myotonic dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10106620

    Blocking CD38 using anti-CD38 F(ab′)2 to protect NK cells

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10106616

    Antagonist antibodies to human prolactin receptor (PRLR)

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10106610

    Antibodies comprising chimeric constant domains

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10107816

    G-protein coupled receptor-associated diagnostics and therapeutics for B-cell chronic lymphocytic leukemia

    The Regents of the University of California · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10106592

    Interleukin-4 receptor-binding fusion proteins and uses thereof

    Medicenna Therapeutics Inc. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10106503

    Biphenyl compounds useful as muscarinic receptor antagonists

    Theravance Biopharma R&D IP, LLC · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10105434

    Immune enhancing recombinant dengue protein

    United States of America as represented by the Secretary of the Air Force · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10105408

    Traditional Chinese medicine composition and preparation method and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10105391

    Chimeric antigen receptor and methods of use thereof

    The Regents of the University of California · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10105379

    Pharmaceutical compositions comprising three antibiotics

    RedHill Biopharma Ltd. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10105316

    Inhalation compositions comprising muscarinic receptor antagonist

    ARVEN ILAC SANAYI VE TICARET A.S. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10104882

    Methods and compositions for preventing and treating electrophile-mediated toxicities

    Montefiore Medical Center · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10105411

    Compositions and methods for modulating AT2R activity

    NOVOPYXIS INC. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10105392

    Isolated renal cells and uses thereof

    inRegen · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10105414

    Peptides derived from RS1 which down-regulate glucose absorption after a glucose rich meal and increase insulin sensitivity

    Julius-Maximilians-Universitat Wurzburg · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10106579

    Modulation of complement activity

    RA PHARMACEUTICALS, INC. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10105416

    Methods of treating mild brain injury

    The Regents of the University of California · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10105523

    Implantable drug delivery device

    Nano Precision Medical, Inc. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10113167

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10111847

    Compounds and methods for modulating vascular injury

    The Regents of the University of California · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10111810

    Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom

    Aquestive Therapeutics, Inc. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10113207

    Methods and compositions for targeted single-stranded cleavage and targeted integration

    Sangamo Therapeutics, Inc. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10111862

    Traps in the treatment of macular degeneration

    Aldeyra Therapeutics, Inc. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10111861

    Treatment of breast cancer

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10111865

    Methods of sedation during critical care treatment

    OVID THERAPEUTICS INC. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10111878

    N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as IDH2 mutants inhibitors for the treatment of cancer

    Agios Pharmaceuticals, Inc. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10111923

    Compositions comprising Cyclocarya paliurus extract and preparation method and uses thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10111927

    Pseudomonas exotoxin A with less immunogenic B cell epitopes

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10111925

    Formulations comprising plant extracts

    MONTERO GIDA SANAYI VE TICARET A.S. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10111926

    Selectively targeted antimicrobial peptides and the use thereof

    The Regents of the University of California · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10111937

    Method of reducing accumulation of intracellular tingible body macrophages

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10112917

    Therapeutic compounds

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10112900

    Modified amino acids

    Sutro Biopharma, Inc. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10111953

    Methods for reducing remnant cholesterol and other lipoprotein fractions by administering an inhibitor of proprotein convertase subtilisin kexin-9 (PCSK9)

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10111957

    Inhalation compositions comprising glucose anhydrous

    ARVEN ILAC SANAYI VE TICARET A.S. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10113145

    Paenibacillus sp. strain, cultivation method and use of the same

    BRIGHT DAIRY & FOOD CO., LTD. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10113170

    Preventing and treating inflammatory skin diseases

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue Oct 30 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.