Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10080740

    Trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors

    Aurigene Discovery Technologies Limited · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10080741

    Isoxazole derivatives as FXR agonists and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10080742

    Isoxazole derivatives as FXR agonists and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10080743

    Isoxazole derivatives as FXR agonists and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10080770

    Cell preparations for extemporaneous use, useful for healing and rejuvenation in vivo

    RegenLab USA LLC · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10080799

    Methods and compositions related to glycoprotein-immunoglobulin fusions

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10080774

    Oncolytic adenovirus armed with therapeutic genes

    The Board of Regents of the University of Texas System · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10080775

    Peptide having skin whitening activity, and use thereof

    CAREGEN CO., LTD. · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10080790

    Staphylococcus aureus materials and methods

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10080803

    Emulsified krill phospholipid compositions

    AKER BIOMARINE ANTARCTIC AS · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10081602

    Opioid agonists and uses thereof

    Nektar Therapeutics · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10081661

    Methods and compositions for genome engineering

    Sangamo Therapeutics, Inc. · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10081658

    Truncated HIV envelope proteins (ENV), methods and compositions related thereto

    The United States of America as represented by the Secretary of the Army · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10081659

    Adeno-associated vectors for enhanced transduction and reduced immunogenicity

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10081668

    Modified pigment epithelium-derived factor (PEDF) peptides and uses thereof for treating neovascular diseases, inflammatory diseases, cancer, and for cytoprotection

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10081632

    Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-α]pyrazine-2-carboxamides as RSK inhibitors

    PHOENIX MOLECULAR DESIGNS · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10081624

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10080718

    Method of treating ear infections

    Try This First, Inc. · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10081811

    Organic compositions to treat Beta-ENaC-related diseases

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10082496

    Targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis

    The Board of Regents of the University of Texas System · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10081670

    Human antibodies to Ebola virus glycoprotein

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10081669

    Therapy for filovirus infection

    The United States of America as represented by the Secretary of the Army · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10081626

    8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists

    Theravance Biopharma R&D IP, LLC · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10080749

    Multi-drug therapies for tuberculosis treatment

    The Regents of the University of California · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10080745

    Piericidin bacterial inhibitors

    The Regents of the University of California Santa Cruz · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10080739

    Aryl imidazoles and their use as anti-cancer agents

    APTOSE BIOSCIENCES INC. · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10081621

    Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10080376

    Method for enhancing postprocessing content of beneficial compounds in beverages naturally containing same

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Sep 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 20 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. EP 3378477

    NEUE THERAPEUTISCHE VERWENDUNGEN VON H3-LIGANDEN

    BIOPROJET PHARMA [FR] · Granted Wed Sep 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Sep 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. WO 2018175449

    COMPOSÉS DE PROLINE AMIDE ET LEURS ANALOGUES D'AZÉTIDINE PORTANT UN RADICAL BENZYLE À SUBSTITUTION SPÉCIFIQUE

    ABBVIE DEUTSCHLAND [DE] · Granted Thu Sep 27 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 22 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10087431

    Methods of generating nucleic acid fragments

    The Regents of the University of California · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10087436

    Electrophysiologically mature cardiomyocytes and methods for making same

    The Regents of the University of California · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10088485

    Methods of screening compounds that can modulate NR2F6 by displacement of a reference ligand

    Regen Biopharma, Inc. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10085951

    Curcuminoid formulations and related methods of treatment

    DESIGNS FOR HEALTH, INC. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10087150

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10086081

    Carbohydrate conjugated RNA agents and process for their preparation

    Alnylam Pharmaceuticals, Inc. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10085997

    Method of treating microbial infections

    The Regents of the University of California · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10085998

    Salts of potassium ATP channel openers and uses thereof

    ESSENTIALIS, INC. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10085990

    Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors

    VTV THERAPEUTICS LLC · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10086008

    Topical antifungal compositions and methods of use thereof

    REVOLUTION PHARMA LLC · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10086041

    Syndecan-4 proteoliposomes for enhanced cutaneous wound healing and minimized inflammatory immune response

    The Board of Regents of the University of Texas System · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10086084

    Activated polyoxazolines and conjugates and compositions comprising the same

    Serina Therapeutics, Inc. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10086088

    Neuronal specific targeting of caveolin expression to restore synaptic signaling and improve cognitive function in the neurodegenerative brain and motor function in spinal cord

    The Regents of the University of California · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10086086

    Payload molecule delivery using molecular rebar

    MOLECULAR REBAR DESIGN, LLC · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10086105

    Chitosan foam medical devices and methods

    Providence Health System—Oregon · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10086091

    Method of preparation of biodegradable nanoparticles with recognition characteristics

    The Board of Regents of the University of Texas System · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10087148

    Quinazolines as biogenic amine transport modulators

    THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10087156

    Methods and compositions related to retinoid receptor-selective pathway

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.