Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2036

Annual patent cliff calendar for 2036 — US pharmaceutical patents by expiration date.

Patents
1,428

Quick answer

1,428 indexed pharmaceutical patents have expiration dates in 2036. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9453028

    Protein kinase C inhibitors and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9453072

    Anti-IL-33 antibodies

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9453220

    RNAi-mediated inhibition of phosphodiesterase type 4 for treatment of cAMP-related ocular disorders

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9453225

    Multiple exon skipping compositions for DMD

    Sarepta Therapeutics, Inc. · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9453222

    Ligand-conjugated monomers

    Alnylam Pharmaceuticals, Inc. · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9453051

    Cyclosporin derivatives

    Lead Discovery Center GmbH · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9453068

    Antibodies that neutralize botulinum neurotoxins

    The Regents of the University of California · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9452973

    Modulators of the relaxin receptor 1

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9452964

    Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses

    Esperion Therapeutics, Inc. · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 9452215

    Bourvadin derivatives and therapeutic uses thereof

    The Regents of the University of Colorado · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9452182

    Collateral gene inactivation biomarkers and targets for cancer therapy

    The Board of Regents of the University of Texas System · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9452186

    Enhanced stem cell composition

    Fate Therapeutics, Inc. · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9452163

    Abuse resistant pharmaceutical compositions

    RECRO GAINESVILLE LLC · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9452221

    Poly(acrylate) polymers for in vivo nucleic acid delivery

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9452161

    Biphenyl compounds useful as muscarinic receptor antagonists

    Theravance Biopharma R&D IP, LLC · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9452175

    Pregnancy hormone combination for treatment of autoimmune diseases

    The Regents of the University of California · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9453239

    Recombinant MVA viruses expressing clade A/G, clade B, and clade C modified HIV env, gag and pol genes

    The Government of the United States of America, as represented by the Secretary Department of Health and Human Services, National Institutes of Health · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9453078

    Modified antibody compositions, methods of making and using thereof

    CytomX Therapeutics, Inc. · Granted Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. DE 202016005375

    Verminderung der Deallylierung von Naloxon während der Lagerung einer naloxonhaltigen Retardformulierung

    ACINO PHARMA AG [CH] · Granted Fri Sep 30 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Sep 25 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9458132

    Therapeutic compounds and compositions and their use as PKM2 modulators

    Agios Pharmaceuticals, Inc. · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9458507

    Antipsychotic treatment based on SNP genotype

    VANDA PHARMACEUTICALS INC. · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9458095

    Oligo-benzamide compounds and their use in treating cancers

    The Board of Regents of the University of Texas System · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9458517

    Adeno-associated virus virions with variant capsid and methods of use thereof

    The Regents of the University of California · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9458442

    Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof

    HALOZYME, INC. · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9458141

    Low molecular weight thyroid stimulating hormone receptor (TSHR) agonists

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9457070

    Compositions, methods and uses of alpha 1-antitrypsin for early intervention in bone marrow transplantation and treatment of graft versus host disease

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9457065

    Methods for delivering insulin preparations into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 9456997

    Selective inhibition of β1-adrenergic receptors for the treatment of pediatric heart failure

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9458215

    Compositions and methods for osteogenic gene therapy

    The United States of America as represented by the Department of Veteran Affairs · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9458225

    Method for purifying lactoferrin

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 9456988

    Swallowable drug delivery device and methods of drug delivery

    Rani Therapeutics, LLC · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 9457030

    Compositions and methods for the treatment of juvenile neuronal ceroid lipofuscinosis and related disorders

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 9457002

    Antimicrobial compositions comprising glyceryl nitrates

    The Board of Regents of the University of Texas System · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 9457006

    Diagnosis and treatment methods for entry of gastrointestinal contents into respiratory tract

    The Regents of the University of California · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 9457052

    Allograft tolerance induction

    United States of America as represented by the Secretary of the Air Force · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 9457067

    Sialylated glycoprotein compositions and uses thereof

    Ultragenyx Pharmaceutical Inc. · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 9457068

    Sialylated glycoprotein compositions and uses thereof

    Ultragenyx Pharmaceutical Inc. · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 9457075

    Modified foot and mouth disease virus (FMDV) VP1 capsid protein

    The Pirbright Institute · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 9457103

    Adeno-associated virus virions with variant capsid and methods of use thereof

    The Regents of the University of California · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 9457132

    Controlled covalent attachment of bioactive bacteriophage for regulating biofilm development

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 9458086

    Compositions and methods for adipocyte modulation

    The United States of America as Represented by the Department of Veterans Affairs Office of General Counsel—PSG IV (024) · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 9458178

    Spiro-oxindole compounds and their use as therapeutic agents

    Xenon Pharmaceuticals Inc. · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9458166

    Oligomer-opioid agonist conjugates

    Nektar Therapeutics · Granted Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9464035

    Salicylic acid derivatives useful as glucocerebrosidase activators

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 11 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 06 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9463195

    Dissolution of amyloid fibrils by flavonoids and other compounds

    The Regents of the University of California · Granted Tue Oct 11 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 06 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 9463247

    Branched alkyl and cycloalkyl terminated biodegradable lipids for the delivery of active agents

    Alnylam Pharmaceuticals, Inc. · Granted Tue Oct 11 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 06 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9464102

    Prodrugs of pyridone amides useful as modulators of sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 11 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 06 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9464130

    Nucleic acids encoding a cold- and menthol-sensitive receptor

    The Regents of the University of California · Granted Tue Oct 11 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 06 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2036?

1,428 published patents in our USPTO index have expiration dates falling in calendar year 2036.