Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8962835

    Imidazopyrazine Syk inhibitors

    GILEAD CONNECTICUT, INC. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 8962566

    Multi-arm polymeric alkanoate conjugates

    Nektar Therapeutics · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 8962685

    Creatine oral supplementation using creatine hydrochloride salt

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 8961993

    Method of treating retinitis pigmentosa

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 8962569

    Compositions comprising spp24 peptide fragments

    The Regents of the University of California · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 8961982

    Modulation of developmental immune programming and protection against cardiovascular disease, diabetes, infectious diseases, and cancer

    The Regents of the University of California · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 8962530

    Inflammatory bowel disease therapies

    The Regents of the University of Colorado · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 8962637

    Bicyclic compounds and their uses as dual c-SRC/JAK inhibitors

    Aurigene Discovery Technologies Limited · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 8962593

    GLA monotherapy for use in cancer treatment

    IMMUNE DESIGN CORP. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 8962631

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 8962561

    Compositions comprising PEDF and uses of same in the treatment and prevention of ovary-related syndromes

    The Fund for Medical Research, Development of Infrastructure and Health Services—Assaf HaRofeh Medical Center · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 8962677

    Methods of restoring cognitive ability using non-peptidic compounds

    Acumen Pharmaceuticals, Inc. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 8962297

    Bacteriophage lytic enzymes as alternative antimicrobials

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 8962551

    Quinoxalinyl derivatives

    Enanta Pharmaceuticals, Inc. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 8962642

    5-cyano-4- (pyrrolo [2,3B] pyridine-3-yl) -pyrimidine derivatives useful as protein kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 8962663

    Small molecule inhibitors of the pleckstrin homology domain and methods for using same

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 8961996

    N-linked glycosylation alteration in E0 and E2 glycoprotein of classical swine fever virus and novel classical swine fever virus vaccine

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 8962847

    Multicomponent crystals made of ([2-amino-6-(4-fluoro-benzylamino)-pyridin-3-yl]-carbamic acid ethyl ester and an arylpropionic acid

    TEVA GmbH · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 8962817

    Vectors encoding a paralytic peptide

    Soricimed Biopharma Inc. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 8962814

    Interleukin-1α antibodies and methods of use

    XBIOTECH INC. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 8962797

    Halogenated compounds for photodynamic therapy

    NANOQUANTUM SCIENCES, INC. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 8962709

    Resin systems for dental restorative materials and methods using same

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 8962824

    Composition of novel carbohydrate drug for treatment of human diseases

    GALECTIN THERAPEUTICS, INC. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 8962653

    Quinolinone-carboxamide compounds as 5-HT4 receptor agonists

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 8962856

    Modulators of cystic fibrosis transmembrane conductance regulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 8962580

    Chemical modifications of monomers and oligonucleotides with cycloaddition

    Alnylam Pharmaceuticals, Inc. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 8961989

    Methods for producing an immune response to tuberculosis

    The United States of America as represented by the Department of Veteran Affairs · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 8962026

    Nanoemulsion therapeutic compositions and methods of using the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 2015057294

    1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS

    ACRAF [IT] · Granted Thu Feb 26 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 21 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 8969653

    Extracellular vesicles derived from gram-positive bacteria, and use thereof

    Aeon Medix Inc. · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 8969413

    Methods of using (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid

    Catalyst Pharmaceuticals, Inc. · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 8969574

    Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 8969409

    Treatment for pulmonary hypertension

    United Therapeutics Corporation · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 8969372

    Aryl imidazoles and their use as anti-cancer agents

    Aptose Boisciences Inc. · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 8969359

    Gyrase and topoisomerase IV inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 8969565

    Imidazo[1,2-b]pyridazine-based compounds, compositions comprising them, and methods of their use

    LEXICON PHARMACEUTICALS, INC. · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 8969356

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 8969287

    Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry

    The Regents of the University of California · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 8968736

    Human antibodies to GFRα3 and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 8968729

    Date pit composition for the treatment of animals

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 8969406

    Use of compound for inhibiting glutathione s-transferase omega 1 activity and method for synthesizing the same

    China Medical University · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 8968234

    Method of using vasoconstrictive agents during energy-based tissue therapy

    Covidien LP · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 8968719

    Live, oral vaccine for protection against Shigella dysenteriae serotype 1

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 8968699

    Switchable nano-vehicle delivery systems, and methods for making and using them

    The Regents of the University of California · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 8968783

    Hydrogel implants with varying degrees of crosslinking

    Covidien LP · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 8969340

    Methods for treating chronic pelvic pain syndrome

    Northwestern University · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 8969292

    High affinity leptins and leptin antagonists

    The Medical Research, Infrastructure and Health Services Fund of the Tel-Aviv Medical Center · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 8968703

    13C-MR detection using hyperpolarised 13C-fructose

    The Regents of the University of California · Granted Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.