Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8952049

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8951998

    Quinoxaline-containing compounds as hepatitis C virus inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8952153

    One pot process for preparing pemetrexed disodium

    Kocak Farma Ilac ve Kimya Sanayi A.S. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8952031

    Amino- and amido-aminotetralin derivatives and related compounds as mu opioid receptor antagonists

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8952032

    Oligomer-opioid agonist conjugates

    Nektar Therapeutics · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8952025

    Multifunctional radical quenchers and their uses

    ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8951964

    Phenanthridine macrocyclic hepatitis C serine protease inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8951794

    Methods and compositions for treating neurodegenerative disorders and Alzheimer's disease and improving normal memory

    The Regents of the University of California · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8951968

    Methods of treating depression and other related diseases

    Northwestern University · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8951551

    Multiribbon nanocellulose as a matrix for wound healing

    The Board of Regents of the University of Texas System · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8951527

    Radioprotectants targeting thrombospondin-1 and CD47

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8951754

    Methods and materials for making simvastatin and related compounds

    The Regents of the University of California · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8951503

    Optical determination of glucose utilizing boronic acid adducts

    The Regents of the University of California · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8951501

    Noninvasive thermometry monitoring system

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8951504

    (trimethoxyphenylamino) pyrimidinyl formulations

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8951971

    Lymphatic zip codes in tumors and pre-malignant lesions

    The Regents of the University of California · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8951793

    Method of making an isolated population of FOXP3+ regulatory T cells

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8951972

    FGFR1 extracellular domain combination therapies for lung cancer

    Five Prime Therapeutics, Inc. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8952062

    Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy

    Jazz Pharmaceuticals, Inc. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8952185

    Production method of optically active dihydrobenzofuran derivative

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8957015

    Tumor suppressor gene p47ING3

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8956646

    Zwitterionic lipids

    The Regents of the University of California · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8956616

    Constructs binding to phosphatidylserine and their use in disease treatment

    The Board of Regents of the University of Texas System · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8956160

    Device and method for delivering an oral care agent

    Ranir, LLC · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8956601

    Therapeutic uses of mastic gum fractions

    REGENERA PHARMA LTD. · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8957047

    GLA monotherapy for use in cancer treatment

    IMMUNE DESIGN CORP. · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8957097

    Hemi-phorboxazole A derivatives and methods of their use

    The Regents of the University of California · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8956828

    Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases

    Sangamo Biosciences, Inc. · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8956831

    Nucleic acids encoding a human monoclonal antibody that specifically binds to IL-1α

    XBIOTECH INC. · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8957192

    Human cytotoxic T-lymphocyte epitope and its agonist epitope from the non-variable number of tandem repeat sequence of MUC-1

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8957188

    Antibodies that bind GalNAc1-3Gal, pharmaceutical compositions and methods of using same

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8957031

    Competitive inhibitors of invariant chain expression and/or ectopic clip binding

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8957223

    Ligand-conjugated monomers

    Alnylam Pharmaceuticals, Inc. · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8957078

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8957069

    Benzofuran derivatives

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8957066

    Histone deacetylase inhibitors

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8957070

    Glucokinase activator compounds, methods of activating glucokinase and methods of treating diabetes and obesity

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8957033

    Inhibitor of sodium-dependent glucose transport protein and preparation method therefor and use thereof

    Beijing Prelude Pharm. SCI. & Tech. Co., Ltd. · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8956864

    Bacterially derived intact minicells that encompass plasmid free functional nucleic acid for in vivo delivery to mammalian cells

    EnGeneIC Molecular Delivery Pty Ltd · Granted Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8962580

    Chemical modifications of monomers and oligonucleotides with cycloaddition

    Alnylam Pharmaceuticals, Inc. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8962653

    Quinolinone-carboxamide compounds as 5-HT4 receptor agonists

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8962026

    Nanoemulsion therapeutic compositions and methods of using the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8962856

    Modulators of cystic fibrosis transmembrane conductance regulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8961989

    Methods for producing an immune response to tuberculosis

    The United States of America as represented by the Department of Veteran Affairs · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8962814

    Interleukin-1α antibodies and methods of use

    XBIOTECH INC. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8962817

    Vectors encoding a paralytic peptide

    Soricimed Biopharma Inc. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8962847

    Multicomponent crystals made of ([2-amino-6-(4-fluoro-benzylamino)-pyridin-3-yl]-carbamic acid ethyl ester and an arylpropionic acid

    TEVA GmbH · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8962824

    Composition of novel carbohydrate drug for treatment of human diseases

    GALECTIN THERAPEUTICS, INC. · Granted Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.