Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8946300

    Use of rasagilline for the treatment of restless legs syndrome

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8946205

    1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors

    Addex Pharma, S.A. · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8946409

    Polycyclic β lactam derivatives for the treatment of cancer

    The Board of Regents of the University of Texas System · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8946172

    Method for reducing scarring during wound healing using antisense compounds directed to CTGF

    Northwestern University · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8946444

    Tetrahydrocarbazoles as active agents for inhibiting VEGF production by translational control

    PTC THERAPEUTICS, INC. · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8945559

    Stabilized formulations containing anti-interleukin-4 receptor (IL-4R) antibodies

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8945604

    Ophthalmic device, and method of use thereof, for increasing ocular boundary lubrication

    The Regents of the University of California · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8946455

    Semi-synthetic small molecules for the treatment parasitic disease

    The Regents of the University of California · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8946424

    Deuterated amlexanox

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8948863

    Photokinetic ocular drug delivery methods and apparatus

    The Board of Regents of the University of Texas System · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8946384

    Polypeptide TF1 for inhibiting type 2 Shiga toxin activity, encoding gene for same and use thereof

    INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY, ACADEMY OF MILITARY MEDICAL SCIENCES, PR CHINA · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8946425

    Processes and intermediates for producing azaindoles

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8945858

    Methods and compositions for treating neurodegenerative disorders and alzheimer's disease and improving normal memory

    The Regents of the University of California · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8946415

    Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use

    LEXICON PHARMACEUTICALS, INC. · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8946398

    Infectious hepatitis C viruses of genotype 3A and 4A and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8946391

    Construction of a multivalent scFv through alkyne-azide 1,3-dipolar cycloaddition

    The Regents of the University of California · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8946243

    Compounds and methods for the treatment of viral infection

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8946379

    Bladder cancer specific ligand peptides

    The Regents of the University of California · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8946291

    Compositions and methods for treating pigmentary conditions and melanoma

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8946285

    Oligomer-opioid agonist conjugates

    Nektar Therapeutics · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8945868

    Methods and compositions for modification of a HLA locus

    The Board of Regents of the University of Texas System · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8946271

    Water soluble furoxan derivatives having antitumor activity

    HUMANITAS MIRASOLE S.P.A. · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8946233

    Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8946194

    One-step processing of hydrogels for mechanically robust and chemically desired features

    The Board of Regents of the University of Texas System · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8946176

    Compositions and methods for inhibiting expression of RRM2 genes

    Arrowhead Research Corporation · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8946167

    Pharmaceutical compositions containing plasma protein

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8946158

    Treatments of gastrointestinal disorders

    IRONWOOD PHARMACEUTICALS, INC. · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8945635

    Formulations comprising extracts from primitive plant species (mosses, ferns and lichens) to treat and prevent cancers

    Southern Connecticut State University · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8946165

    Compounds for reversing and inhibiting protein aggregation, and methods for making and using them

    The Regents of the University of California · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8945602

    Porous photonic crystals for drug delivery to the eye

    The Regents of the University of California · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8945595

    Insect repellent and attractants

    The Regents of the University of California · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8945587

    Synthetic lipid biology for combinatorial engineering of endotoxin

    The Board of Regents of the University of Texas System · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8945508

    Dendrimer compositions and methods of synthesis

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8945544

    Immunogenic compositions comprising progastrin and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8945482

    System, method and device for tissue-based diagnosis

    The Regents of the University of California · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8946382

    Apelin peptides and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8945108

    Method of using vasoconstrictive agents during energy-based tissue therapy

    Covidien LP · Granted Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 29 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. WO 2015016729

    COMPOSÉS D'URÉE ET LEUR UTILISATION COMME INHIBITEURS DE L'ENZYME FAAH

    BIAL PORTELA & Cª S A [PT] · Granted Thu Feb 05 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. CA 2919844

    COMPOSES D'UREE ET LEUR UTILISATION COMME INHIBITEURS DE L'ENZYME FAAH

    BIAL PORTELA & CA SA [PT] · Granted Thu Feb 05 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 2015038439

    METHOD FOR PREPARING SUSPENSIONS OF LOW-SOLUBILITY MATERIALS

    MACLEOD STEVEN K [US] · Granted Thu Feb 05 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. WO 2015016728

    COMPOSÉS D'URÉE ET LEUR UTILISATION COMME INHIBITEURS DE L'ENZYME FAAH

    BIAL PORTELA & Cª S A [PT] · Granted Thu Feb 05 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8952029

    Method of administration of gamma hydroxybutyrate with monocarboxylate transporters

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8952169

    N-substituted benzamides and methods of use thereof

    Xenon Pharmaceuticals Inc. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8952161

    Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8952067

    Subcutaneous fat reduction

    Atheronova Operations, Inc. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8952065

    Acetylcysteine composition and uses thereof

    Cumberland Pharmaceuticals Inc. · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8952129

    Method of treating degenerative diseases

    The Board of Regents of the University of Texas System · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8952050

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 05 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.