Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9157916

    Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays

    The Board of Regents of the University of Texas System · Granted Tue Oct 13 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9163022

    Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors

    VTV THERAPEUTICS LLC · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9163271

    Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs

    The Regents of the University of California · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9163245

    Compositions for linking zinc finger modules

    Sangamo Biosciences, Inc. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9163235

    Inhibitors of the miR-15 family of micro-RNAs

    MIRAGEN THERAPEUTICS, INC. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9163085

    Anti-OX40 antibodies and methods of treating cancer

    The Board of Regents of the University of Texas System · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9163215

    Generation of lineage-restricted progenitor cells from differentiated cells

    The Regents of the University of California · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9163244

    Suppressors of CpG oligonucleotides and methods of use

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9163236

    Pharmaceutical composition comprising NANOG SHRNA, and method of using NANOG SHRNA to treat cancer

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 9163248

    Targeting pseudotyped retroviral vectors

    The Regents of the University of California · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9163042

    Prodrugs of pyridone amides useful as modulators of sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9162968

    Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis

    Northwestern University · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9161735

    Systems, compositions, and methods for local imaging and treatment of pain

    The Regents of the University of California · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9162982

    4-[2-(2-fluorophenoxy methyl)phenyl]piperidine compounds

    Theravance Biopharma R&D IP, LLC · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9161984

    Formulations and methods of use for alpha connexin C-terminal (ACT) peptides

    FIRSTSTRING RESEARCH, INC. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9161936

    Laquinimod for treatment of GABA mediated disorders

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9161995

    Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene

    Sangamo Biosciences, Inc. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9161948

    Peptide oligonucleotide conjugates

    Sarepta Therapeutics, Inc. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9161935

    Use of laquinimod for treating Crohn's disease patients who failed first-line anti-TNF therapy

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9161969

    Protection against influenza infection by granulocyte-macrophage colony stimulating factor

    The Board of Regents of the University of Texas System · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9161990

    Hydrochloride salts of a glycopeptide-cephalosporin antbiotic compond

    THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9162980

    Anti-depression compounds

    The Board of Regents of the University of Texas System · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9163068

    Influenza virus recombinant proteins

    The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9163258

    Method for the treatment of obesity

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9162989

    2,4-Pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9169326

    Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers

    PRECISION BIOLOGICS, INC. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9169238

    Solid pharmaceutical composition

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 9168262

    Estriol therapy for multiple sclerosis and other autoimmune diseases

    The Regents of the University of California · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9169297

    Subgenomic replicons of the flavivirus dengue

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9167841

    Tangerine peel extract and its preparation and application

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 9169509

    Topoisomerase 2b as a predictor of susceptibility to anthracycline-induced cardiotoxicity

    The Board of Regents of the University of Texas System · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 9168266

    Hybrid diazeniumdiolated compounds, pharmaceutical compositions, and method of treating cancer

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 9168227

    Multi-encapsulated microspheres made with oxidized cellulose for in-situ reactions

    Covidien LP · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 9168261

    Compositions and methods for cartilage repair

    REGENERATIVE SCIENCES, LLC · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 9168269

    Inhibitors of long and very long chain fatty acid metabolism as broad spectrum anti-virals

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 9168291

    β-mannosylceramide and stimulation of NKT cell anti-tumor immunity

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 9169296

    Expression and assembly of human group C rotavirus-like particles and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 9169350

    N-maleimidyl polymer derivatives

    Nektar Therapeutics · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 9169495

    Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells

    EnGeneIC Molecular Delivery Pty Ltd · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 9169280

    Methods for the synthesis of plasmalogens and plasmalogen derivatives, and therapeutic uses thereof

    Phenomenome Discoveries Inc. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 9168311

    Oligomer-dantrolene conjugates and related compounds

    Nektar Therapeutics · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 9168297

    Regulation of skin pigmentation by neuregulin-1 (NRG-1)

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9169354

    Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same

    Serina Therapeutics, Inc. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9169321

    Activatable binding polypeptides and methods of identification and use thereof

    The Regents of the University of California · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9169313

    Method of treatment of cancers characterized by ligand-dependent activating mutations in FGFR2 with FGFR1 ECD proteins

    Five Prime Therapeutics, Inc. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 9169303

    Vault compositions for immunization

    The Regents of the University of California · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9169294

    Anti-angiogenic molecules, nanostructures and uses thereof

    Northwestern University · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9169249

    Protein kinase C inhibitors and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.