Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9085577

    7-aryl-1,2,4-triazolo[4,3-A]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors

    Addex Pharma, S.A. · Granted Tue Jul 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9084828

    Oligomer-protein tyrosine kinase inhibitor conjugates

    Nektar Therapeutics · Granted Tue Jul 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9084761

    Use of interleukin-15 to treat cardiovascular diseases

    THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Jul 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9085757

    Production of insulin producing cells

    Regents of the University of Minnesota · Granted Tue Jul 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9086420

    Methods for identifying analgesic agents

    Xenon Pharmaceuticals Inc. · Granted Tue Jul 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9084808

    Modified small interfering RNA molecules and methods of use

    Arrowhead Research Corporation · Granted Tue Jul 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9090573

    Compounds as lysophosphatidic acid receptor antagonists

    AMIRA PHARMACEUTICALS, INC. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9090630

    Macrocyclic FLT3 kinase inhibitors

    Oncodesign SA · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9090712

    Diagnosis of carcinomas

    PACIFIC NORTHWEST RESEARCH INSTITUTE · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 9090895

    Compositions and methods for inhibiting expression of the HAMP gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9091696

    Modulation of NR2F6 and methods and uses thereof

    Regen Biopharma, Inc. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9090597

    Pyrazolone derivatives as PDE4 inhibitors

    TAKEDA GMBH · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9091701

    Disease severity index for assessment of chronic liver disease and method for diagnosis of three distinct subtypes of primary sclerosing cholangitis

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9090740

    Methods for preparing polymeric reagents

    Nektar Therapeutics · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9090619

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9089482

    Dental mill blank

    KURARAY NORITAKE DENTAL INC. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9089498

    Multifunctional nanoparticle designs and applications

    The Regents of the University of California · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9089156

    Reducing muscle soreness with glucosamine compositions

    Stokely-Van Camp, Inc. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9090873

    Development of dengue virus vaccine components

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9089515

    Long chain N-alkyl compounds and oxa-derivatives thereof

    United Therapeutics Corporation · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9090933

    Cancer screening by detection of ultrastructural and molecular markers

    Northwestern University · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9089531

    GABA agonists in the treatment of disorders associated with metabolic syndrome and GABA combinations in treatment or prophylaxis of type I diabetes

    The Regents of the University of California · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9089566

    Delivery of therapeutic compounds to the brain and other tissues

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9089599

    Low affinity FCGR deficient mice

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9089610

    Complexes of small-interfering nucleic acids

    Nektar Therapeutics · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9089677

    Transcutaneous multimodal delivery system (TMDS)

    The Regents of the University of California · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9089555

    Complement antagonists and uses thereof

    REGENESANCE B.V. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 9089556

    Method for treating cancer using an antibody that inhibits notch4 signaling

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9089611

    Poly(vinyl ester) polymers for in vivo nucleic acid delivery

    Arrowhead Madison, Inc. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9089698

    Method and apparatus for optogenetic treatment of blindness including retinitis pigmentosa

    The Regents of the University of California · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 9090535

    Hydroxylated tricyclic compounds

    Nektar Therapeutics · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 9090586

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 9090589

    Specific nNOS inhibitors for the therapy and prevention of human melanoma

    The Regents of the University of California · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 9090598

    Nilotinib salts and crystalline forms thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 9090614

    Processes and intermediates for producing azaindoles

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 9089506

    Stable, non-irritating topical formulations of hydroquinone

    Precision Dermatology, Inc. · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 9089545

    Small molecule RNase inhibitors and methods of use

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Jul 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. FR 3016881

    TRAITEMENT DES DEGENERESCENCES ET DES LESIONS PHOTO-INDUITES DE LA RETINE

    BIOCODEX [FR] · Granted Fri Jul 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Jul 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 9096499

    Compounds for treatment of cell proliferative diseases

    The Board of Regents of the University of Texas System · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 9096543

    Nuclear transport modulators and uses thereof

    Karyopharm Therapeutics Inc. · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 9096584

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 9096602

    Substituted pyrrolo[2,3-B]pyrazines as ATR kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9096608

    Pharmaceutically active pyrazolo-triazine derivatives

    Lead Discovery Center GmbH · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9096609

    Macrocyclic LRRK2 kinase inhibitors

    Oncodesign SA · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9096642

    Therapeutic compounds for immunomodulation

    Aurigene Discovery Technologies Limited · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 9096637

    Organic compositions to treat HSF1-related diseases

    Arrowhead Research Corporation · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9096647

    Simplified one-pot synthesis of [18F]SFB for radiolabeling

    The Regents of the University of California · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9096689

    Methods and compositions for inhibiting angiogenesis

    Northwestern University · Granted Tue Aug 04 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 30 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.