Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2033

Annual patent cliff calendar for 2033 — US pharmaceutical patents by expiration date.

Patents
1,330

Quick answer

1,330 indexed pharmaceutical patents have expiration dates in 2033. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8367810

    Purified plasmodium and vaccine compositions

    Sanaria Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 8367694

    Carboline derivatives useful in the inhibition of angiogenesis

    PTC THERAPEUTICS, INC. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 8367691

    Modulators of muscarinic receptors

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 8367672

    Pyridazine compounds, compositions and methods

    Northwestern University · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 8367697

    Kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 8367660

    Modulators of cystic fibrosis transmembrane conductance regulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 8367655

    Pyridoindolobenzox—and thiazepine derivatives and uses thereof

    DAYA DRUG DISCOVERIES, INC. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 8367120

    Method and apparatus for producing a stablized antimicrobial non-toxic electrolyzed saline solution exhibiting potential as a therapeutic

    Reoxcyn Discoveries Group, Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 8367734

    Stable epinephrine suspension formulation with high inhalation delivery efficiency

    Amphastar Pharmaceuticals, Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 8367638

    Galactose-pronged polysaccharides in a formulation for antifibrotic therapies

    GALECTIN THERAPEUTICS, INC. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 8367618

    Cyclosporin analogues for preventing or treating hepatitis C infection

    Enanta Pharmaceuticals, Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 8367401

    Replication competent hepatitis C virus and methods of use

    The Board of Regents of the University of Texas System · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 8367099

    Perforated fatty acid films

    ATRIUM MEDICAL CORPORATION · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 8367105

    Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 8365314

    Coated elastomeric article and method for making a coated elastomeric article

    Precision Components, Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 8367074

    Recovery of recombinant human parainfluenza virus type 2 (HYPIV2) from cDNA and use of recombinant HPIV2 in immunogenic compositions and as vectors to elicit immune responses against PIV and other human pathogens

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 8367058

    Method for bacteriophage delivery and amplification

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 8366660

    Drug releasing coatings for medical devices

    Lutonix, Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 8367053

    Cyclosporin analogues

    Enanta Pharmaceuticals, Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. DE 102011080389

    Schutzfolienwechsler

    ACINO AG [DE] · Granted Thu Feb 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 8372877

    Stabilized statin formulations

    Cumberland Pharmaceuticals Inc. · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 8372848

    Melanin-concentrating hormone receptor antagonists and methods of use

    The Regents of the University of California · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 8372800

    Albumin-free factor VIII formulations

    UNIVERSITY OF CONNECTICUT · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 8372860

    Carboline derivatives useful in the inhibition of angiogenesis

    PTC THERAPEUTICS, INC. · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 8372984

    Dual-acting oxazole antihypertensive agents

    Theravance, Inc. · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 8372979

    Process for the production of high-purity 2,4′-dimethyl-3-piperidino-propiophenone (tolperisone), pharmaceutical compositions that contain the latter, as well as active ingredient formulations that contain tolperisone

    SANOCHEMIA PHARMAZEUTIKA AG · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 8372883

    Methods of using cycloalkylmethylamines

    REVIVA PHARMACEUTICALS, INC. · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 8372850

    Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 8372873

    Inhibitors of serine proteases

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 8372872

    Methods for concomitant treatment of theophylline and febuxostat

    Takeda Pharmaceuticals U.S.A., Inc. · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 8372846

    Co-crystals and pharmaceutical compositions comprising the same

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 8372835

    Pyrrolopyrazines and pyrazolopyrazines useful as inhibitors of protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 8372826

    Estriol therapy for multiple sclerosis and other autoimmune diseases

    The Regents of the University of California · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 8372812

    Phospholipid and protein tablets

    Aker Biomarine AS · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 8372802

    Fluorinated macrocyclic compounds as hepatitis C virus inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 8372843

    Quinolines useful as modulators of ION channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 8372422

    Hydroxyapatite-targeting poly(ethylene glycol) and related polymers

    Nektar Therapeutics · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 8372435

    Modular monolayer coatings for selective attachment of nanoparticles to biomolecules

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 8372415

    Wet granulation using a water sequestering agent

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 8372380

    In vivo imaging of sulfotransferases

    The Regents of the University of California · Granted Tue Feb 12 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. EP 2555769

    VERFAHREN ZUR BEHANDLUNG VON VIRALEN ATEMWEGSINFEKTIONEN

    CELGENE CORP [US] · Granted Wed Feb 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Feb 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 2013041307

    APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT

    CERAMOPTEC IND INC [DE] · Granted Thu Feb 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 8378121

    Quaternary ammonium diphenylmethyl compounds useful as muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Feb 19 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 8378084

    Fusion molecule based on novel TAA variant

    The Regents of the University of California · Granted Tue Feb 19 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 8378124

    Preparation of protected alpha-keto beta-amino esters and amides

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 19 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 8378071

    Peptide epitopes of VEGFR-2/KDR that inhibit angiogenesis

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Feb 19 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 8378109

    Labeled ALPHA4BETA2 ligands and methods therefor

    The Regents of the University of California · Granted Tue Feb 19 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 8377964

    Benzimidazole-carboxamide compounds as 5-HT4 receptor agonists

    Theravance, Inc. · Granted Tue Feb 19 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2033?

1,330 published patents in our USPTO index have expiration dates falling in calendar year 2033.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.