Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2033

Annual patent cliff calendar for 2033 — US pharmaceutical patents by expiration date.

Patents
1,330

Quick answer

1,330 indexed pharmaceutical patents have expiration dates in 2033. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8357783

    Human anti-mesothelin monoclonal antibodies

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 8357718

    Compounds and methods for the treatment or prevention of flavivirus infections

    Vertex Pharmaceuticals (Canada) Incorporated · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 8357676

    Ansamycin formulations and methods of use thereof

    Infinity Discovery, Inc. · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 8357656

    Natriuretic peptide receptor-C agonists

    Regents of the University of Minnesota · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 8357374

    Conjugates of synthetic TLR agonists and uses therefor

    The Regents of the University of California · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 8357697

    Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 8357525

    Thermal inactivation of rotavirus

    The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 8357702

    Bicyclic derivatives as modulators of voltage gated ion channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 8357379

    High concentration baclofen preparations

    The Board of Regents of the University of Texas System · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 8357361

    Bioabsorbable surgical composition

    Covidien LP · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 8357353

    Compositions comprising a UV-absorbing chromophore

    United States Department of Agriculture · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 8357371

    Methods for treating hypercholesterolemia using antibodies to PCSK9

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 8357365

    Granulysin peptides and methods of use thereof

    The Regents of the University of California · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 8357534

    Isolation of human articular cartilage stem cells

    University College Cardiff Consultants Limited · Granted Tue Jan 22 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. EP 2548561

    Semuloparin zur Verbesserung der Überlebenschancen von Patienten mit örtlich fortgeschrittenem Krebs

    AVENTIS PHARMA SA [FR] · Granted Wed Jan 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Jan 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 2013023492

    PHARMACEUTICAL COMPOSITIONS COMPRISING PLANT-BASED POLYSACCHARIDES AND USES THEREOF

    MARLOWE ZORA T [US] · Granted Thu Jan 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 2013023524

    TRICYCLIC INDAZOLE COMPOUND, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING IT

    ACRAF [IT] · Granted Thu Jan 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 8362043

    Caspase inhibitors and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 8362032

    Bicyclic derivatives as modulators of ion channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 8362060

    Crystalline forms of an alkoxyimidazol-1-ylmethyl biphenyl carboxylic acid

    Theravance, Inc. · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 8361968

    Metastin derivatives and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 8361958

    Oximyl HCV serine protease inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 8361756

    Bifidobacterial gene sequences and their use

    The Regents of the University of California · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 8361772

    Specific lysis of staphylococcal pathogens by bacteriophage phi11 endolysin

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 8361768

    Heat resistant bioactive composition

    Regents of the University of Minnesota · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 8361733

    Methods of identifying modulators of a cold-and-menthol-sensitive receptor (CMR1) and recombinant cells for use thereof

    The Regents of the University of California · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 8361710

    MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer using miR-21

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 8361471

    Immunostimulatory regimen comprising administering type 1 interferon and agonistic anti-CD40 antibody

    The Regents of the University of Colorado · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 8361485

    Conditioned cell culture medium compositions and methods of use

    SkinMedica, Inc. · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 8361707

    Methods for detecting a Mycobacterium tuberculosis infection

    The United States of America—Department of Veterans Affairs · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 8361508

    Endocytotic particles

    The Board of Regents of the University of Texas System · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 8362211

    Anti-CD38 antibodies

    Takeda Pharmaceutical Company Limited · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 8361982

    Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell

    The Regents of the University of California · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 8361459

    Treatment of stroke and other acute neural degenerative disorders using postpartum-derived cells

    Advanced Technologies and Regenerative Medicine, LLC · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 8361743

    Biological production of zeaxanthin and carotenoid biosynthesis control

    Aquapharm Bio-Discovery Ltd. · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 8360765

    Systems and method for forming a coaxial implant

    Covidien LP · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 8362253

    Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 8362277

    Pro-neurogenic compounds

    The Board of Regents of the University of Texas System · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 8362235

    Carboxamide compounds and methods for using the same

    Rigel Pharmaceuticals, Inc. · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 8362044

    N,N-disubstituted aminoalkylbiphenyl antagonists of prostaglandin D2 receptors

    Panmira Pharmaceuticals, LLC · Granted Tue Jan 29 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. WO 2013015774

    DIHYDROXY-CHLORINES GLYCO-SUBSTITUÉES ET CHLORINES BÊTA-FONCTIONNALISÉES POUR THÉRAPIE ANTIMICROBIENNE PHOTODYNAMIQUE

    BIOLITEC PHARMA MARKETING LTD [MY] · Granted Thu Jan 31 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 26 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. WO 2013014107

    SÉMULOPARINE POUR L'AMÉLIORATION DE LA SURVIE DE PATIENTS ATTEINTS D'UN CANCER

    AVENTIS PHARMA SA [FR] · Granted Thu Jan 31 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 26 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 8366662

    Drug releasing coatings for medical devices

    Lutonix, Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 8367053

    Cyclosporin analogues

    Enanta Pharmaceuticals, Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 8365314

    Coated elastomeric article and method for making a coated elastomeric article

    Precision Components, Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 8367841

    Processes for the preparation of 1,2,4-oxadiazole benzoic acids

    PTC THERAPEUTICS, INC. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 8367810

    Purified plasmodium and vaccine compositions

    Sanaria Inc. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 8367694

    Carboline derivatives useful in the inhibition of angiogenesis

    PTC THERAPEUTICS, INC. · Granted Tue Feb 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2033?

1,330 published patents in our USPTO index have expiration dates falling in calendar year 2033.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.