Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2033

Annual patent cliff calendar for 2033 — US pharmaceutical patents by expiration date.

Patents
1,330

Quick answer

1,330 indexed pharmaceutical patents have expiration dates in 2033. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 2013209398

    CONDITIONED CELL CULTURE MEDIUM COMPOSITIONS AND METHODS OF USE

    ALLERGAN INC [US] · Granted Thu Aug 15 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 10 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 2013210912

    Ophthalmic Pharmaceutical Compositions and Methods of Making and Using Same

    BAUSCH & LOMB [US] · Granted Thu Aug 15 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 10 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. AU 2012210489

    IL17 and IFN-gamma inhibition for the treatment of autoimmune inflammation

    4SC DISCOVERY GMBH [DE] · Granted Thu Aug 15 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 10 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. AU 2012210491

    IL17 and IFN-gamma inhibition for the treatment of autoimmune inflammation

    4SC DISCOVERY GMBH [DE] · Granted Thu Aug 15 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 10 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8512964

    Targets for treatment of hypercholesterolemia

    The Regents of the University of California · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8513198

    Pharmaceutical formulation for reducing pain

    Jazz Pharmaceuticals International III Limited · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8513252

    Pyrazole derivatives and their use as positive allosteric modulators of metabotropic glutamate receptors

    Addex Pharma, S.A. · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8513432

    Dual-acting benzoimidazole antihypertensive agents

    Theravance, Inc. · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8512258

    Breath test device and method

    EXALENZ BIOSCIENCE LTD. · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8512693

    Self-assembling membranes and related methods thereof

    Northwestern University · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8512712

    Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions

    ONCOLYTICS BIOTECH INC. · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8512746

    Extended release pharmaceutical compositions of levetiracetam

    SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETI · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8512755

    Compact multifunctional ligand to enhance colloidal stability of nanoparticles

    United States of America as represented by the Secretary of the Air Force · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8512991

    Beta 1,4-galactosyltransferases with altered donor and acceptor specificities, compositions and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8513005

    DNA immunogenic composition comprising a full-length modified poxvirus L1R gene fused to a tPA leader sequence

    The United States of America as represented by the Secretary of the Army · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8513197

    Ganglioside epitopes for treating Guillain-Barre syndrome

    Georgia Regents University · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8513214

    C4′-substituted-2-deoxyadenosine analogs and methods of treating HIV

    The United States of America as represented by the Secretary of the Dept. of Health & Human Services · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8513230

    Nuclear transport modulators and uses thereof

    Karyopharm Therapeutics Inc. · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8513244

    Neprilysin inhibitors

    Theravance, Inc. · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8513251

    Pyridazinone compounds

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8513279

    Quinuclidine derivatives and medicinal compositions containing the same

    Almirall, S.A. · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8513302

    Reducing nephropathy with inhibitors of soluble epoxide hydrolase and epoxyeicosanoids

    The Regents of the University of California · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8513390

    Modified antibody compositions, methods of making and using thereof

    CytomX Therapeutics, Inc. · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8513414

    Processes and intermediates for producing azaindoles

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8513489

    Uses of antimicrobial genes from microbial genome

    The Regents of the University of California · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8512751

    Pharmaceutical compositions for sleep disorders

    Collegium Pharmaceutical, Inc. · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8513209

    Micro-RNAS of the MIR-15 family modulate cardiomyocyte survival and cardiac repair

    The Board of Regents of the University of Texas System · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8513282

    Modulators of cystic fibrosis transmembrane conductance regulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 20 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8518390

    Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells

    Advanced Technologies and Regenerative Medicine, LLC · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8518871

    Skin permeating and cell entering (SPACE) peptides and methods of use thereof

    The Regents of the University of California · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8518890

    Remedies for sex hormone dependent disease

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8518884

    Methods for treating atrial or ventricular arrhythmias by administering a G-protein alpha inhibitor

    Northwestern University · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8518870

    Compositions and methods for cancer treatment using targeted carbon nanotubes

    The Board of Regents of the University of Oklahoma · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8518887

    Method of treating cancer with DLL4 antagonist and chemotherapeutic agent

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8518968

    Hydrazone and diacyl hydrazine compounds and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8519086

    Degradable thiol-ene polymers

    The Regents of the University of Colorado · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8518937

    Pyrimidinediamine kinase inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8518647

    Method of diagnosing poor survival prognosis colon cancer using miR-16b

    The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8519102

    Polymer Factor VIII moiety conjugates

    Nektar Therapeutics · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8519002

    Colchicine solid complex; methods of making; and methods of use thereof

    Takeda Pharmaceuticals U.S.A., Inc. · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8519137

    Heteroaryl amides useful as inhibitors of voltage-gated sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8518980

    Treatment of Duchenne muscular dystrophy

    Summit Corporation Plc · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8518984

    Spiro-oxindole MDM2 antagonists

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8519103

    Factor VII polypeptides that are modified and uses thereof

    Catalyst Biosciences, Inc. · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8519158

    Androgen receptor modulator compounds and methods

    Ligand Pharmaceuticals Incorporated · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8518957

    Methanocarba adenosine derivatives, pharmaceutical compositions, and method of reducing intraocular pressure

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8518953

    Aminopyrimidines useful as inhibitors of protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8518938

    c-MET protein kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 27 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2033?

1,330 published patents in our USPTO index have expiration dates falling in calendar year 2033.