Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2033

Annual patent cliff calendar for 2033 — US pharmaceutical patents by expiration date.

Patents
1,330

Quick answer

1,330 indexed pharmaceutical patents have expiration dates in 2033. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8501713

    Drug combinations for the treatment of duchenne muscular dystrophy

    Summit Corporation Plc · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8501704

    Immunosuppression compound and treatment method

    Sarepta Therapeutics, Inc. · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8501688

    SCGB3A2 as a growth factor and anti-apoptotic agent

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8501695

    Tissue kallikrein for the treatment of diseases associated with amyloid protein

    DiaMedica Inc. · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8501705

    Methods and materials for treating autoimmune and/or complement mediated diseases and conditions

    The Board of Regents of the University of Texas System · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8501692

    Compositions and methods for altering cocaine esterase activity

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8501682

    Difluorinated tripeptides as HCV serine protease inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8501681

    Macrocyclic hepatitis C virus serine protease inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8501466

    Vector

    The Pirbright Institute · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8501678

    Variant activin receptor polypeptides and uses thereof

    Atara Biotherapeutics, Inc. · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8501423

    Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays

    The Board of Regents of the University of Texas System · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8501194

    Vaccine for viruses that cause persistent or latent infections

    The Regents of the University of California · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8501229

    Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings

    ATRIUM MEDICAL CORPORATION · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8501191

    FGFR2-IIIb fusion proteins and methods of making them

    Five Prime Therapeutics, Inc. · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8501188

    Method of treating inflammatory lung disease with suppressors of CpG oligonucleotides

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8501722

    Methods and compositions for treating bacterial infection

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. BR PI0714667

    conjugado molecular e respectivo uso

    CERAMOPTEC IND INC [US] · Granted Tue Aug 06 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. EP 2623110

    Faktor-XII-Hemmer zur Behandlung neurologischer Entzündungserkrankungen

    CSL BEHRING GMBH [DE] · Granted Wed Aug 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Aug 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8507534

    Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8507661

    Modified iRNA agents

    Alnylam Pharmaceuticals, Inc. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8507675

    Compositions and methods for inhibition of the JAK pathway

    Rigel Pharmaceuticals, Inc. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8507687

    Solid forms of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8507672

    Substituted pyrrolo[2,3-d]pyrimidines as LIM kinase 2 inhibitors

    LEXICON PHARMACEUTICALS, INC. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8507551

    Antimicrobial therapy for bacterial infections

    The Regents of the University of California · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8507447

    Treatments for gastrointestinal disorders

    IRONWOOD PHARMACEUTICALS, INC. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8506928

    Methods and compounds for targeting tissues

    The Regents of the University of California · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8507012

    Formulations comprising extracts from primitive plant species (mosses, ferns and lichens) to treat and prevent cancers

    Southern Connecticut State University · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8506947

    Vaccinia virus expression vector for selective replication in a tumor cell and introduction of exogenous nucleotide sequence into a tumor cell

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8506959

    Prevention and treatment of synucleinopathic and amyloidogenic disease

    The Regents of the University of California · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8506961

    Humanized monoclonal antibodies that specifically bind and/or neutralize japanese encephalitis virus (JEV) and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8507195

    MiRNAs dysregulated in triple-negative breast cancer

    The Regents of the University of Colorado · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8507433

    Cardioprotective effects of GHRH agonists

    THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8507435

    Juvenile hemochromatosis gene (HFE2A) cleavage products and uses thereof

    Xenon Pharmaceuticals Inc. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8507206

    Monoclonal antibodies that target pathological assemblies of amyloid β (Abeta)

    Acumen Pharmaceuticals, Inc. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8507437

    Apoptosis-modulating p53 protein therapy for vascular disorders and nanoparticles containing the same

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8507445

    Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer

    The Board of Regents of the University of Texas System · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8507463

    Nucleotide analogue prodrug and the preparation thereof

    BrightGene Bio-Medical Technology Co., Ltd. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8507524

    Modulators of ATP-binding cassette-transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8507455

    Folate conjugates

    Alnylam Pharmaceuticals, Inc. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8507522

    Hepatitis C virus inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8507536

    Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8507663

    Compositions and methods for inhibiting expression of CD274/PD-L1 gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8506944

    Replenishment and enrichment of ocular surface lubrication

    The Regents of the University of California · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8507653

    Factor IX moiety-polymer conjugates having a releasable linkage

    Nektar Therapeutics · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8507552

    Triptolide prodrugs

    Regents of the University of Minnesota · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8507650

    Use of bacteriophage outer membrane breaching proteins expressed in plants for the control of gram-negative bacteria

    INTEGRATED PLANT GENETICS, INC. · Granted Tue Aug 13 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. EP 2624836

    BEPOTASTIN-ZUSAMMENSETZUNG

    BAUSCH & LOMB [US] · Granted Wed Aug 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Aug 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 2013209398

    CONDITIONED CELL CULTURE MEDIUM COMPOSITIONS AND METHODS OF USE

    ALLERGAN INC [US] · Granted Thu Aug 15 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 10 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2033?

1,330 published patents in our USPTO index have expiration dates falling in calendar year 2033.