Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2033

Annual patent cliff calendar for 2033 — US pharmaceutical patents by expiration date.

Patents
1,330

Quick answer

1,330 indexed pharmaceutical patents have expiration dates in 2033. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8481024

    Vaccines against tularemia

    The Regents of the University of California · Granted Tue Jul 09 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 04 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8480995

    Use of sodium selenosulfate for supplementing selenium and enhancing the therapeutic efficacy of chemotherapy agents, and a rapid process for preparing sodium selenosulfate

    UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA · Granted Tue Jul 09 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 04 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8481521

    Methods of treating cell proliferative disorders

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 09 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 04 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8480637

    Nanochanneled device and related methods

    The Board of Regents of the University of Texas System · Granted Tue Jul 09 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 04 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 2013178639

    CRYSTALLINE FORMS OF DIMETHOXY DOCETAXEL AND METHODS FOR PREPARING THE SAME

    AVENTIS PHARMA SA [FR] · Granted Thu Jul 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jul 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8486370

    Heterocyclic ligands for integrin imaging and therapy

    The Regents of the University of California · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8486410

    RLIP76 liposomes for protection against irradiation

    The Board of Regents of the University of Texas System · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8486428

    Compositions and methods for making and using acyclic N-halamine-based biocidal polymeric materials and articles

    The Board of Regents of the University of Texas System · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8486450

    Method of producing solid preparation disintegrating in the oral cavity

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8486423

    Thermo-kinetic mixing for pharmaceutical applications

    The Board of Regents of the University of Texas System · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8486898

    Compounds and method for inhibiting the activity of gelatinase and collagenase

    China Medical University · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8486699

    Immortal unipotent porcine PICM-19H and PICM-19B stem cell lines

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8486923

    Use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis

    TAKEDA GMBH · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8486909

    Compositions and methods for the diagnosis and treatment of inflammatory disorders and fibrotic disease

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8486928

    Super-oxide dismutase mimetics

    Galera Therapeutics, LLC · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8486958

    Crystalline forms of a 3-carboxypropyl-aminotetralin compound

    Theravance, Inc. · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8486935

    Xinafoate salt of N4-(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy)phenyl]2,4-pyrimidinediamine

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8486981

    Selective ligands for the dopamine 3 (D3) receptor and methods of using the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8486391

    Cancer treatment kits using antibodies to aminophospholipids

    The Board of Regents of the University of Texas System · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8487077

    Simplified one-pot synthesis of [18F]SFB for radiolabeling

    The Regents of the University of California · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8486385

    Methods for therapy of neurodegenerative disease of the brain

    The Regents of the University of California · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8486965

    Pyrrolo[2,3-b]pyridine derivative and use thereof for treatment of cancer

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8486989

    Inhibitors of serine proteases, particularly HCV NS3-NS4A protease

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8486982

    1,2,4-oxadiazole benzoic acids

    PTC THERAPEUTICS, INC. · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8486433

    Antibacterial deodorant

    JGC Catalysts and Chemicals Ltd. · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8487097

    Reference standard for characterization of rosuvastatin

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8487107

    Biphenyl compounds useful as muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Jul 16 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8492546

    Co-crystals and pharmaceutical compositions comprising the same

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8492345

    Cyclic peptide antitumor agents

    Northwestern University · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8492378

    GSK-3β inhibitor

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8492397

    Aminopyridine derivatives having Aurora A selective inhibitory action

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8492503

    Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method

    Nektar Therapeutics · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8492454

    Removable color layer for artificial nail coatings and methods therefore

    Creative Nail Design Inc. · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8492428

    Small-molecule botulinum toxin inhibitors

    The United States of America as represented by the Secretary of the Army · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8492488

    Stabilized polymeric thiol reagents

    Nektar Therapeutics · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8492430

    Fused cyclic compounds

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8491880

    Pharmaceutical formulations of biodegradable biocompatible camptothecin-polymer conjugates

    Mersana Therapeutics, Inc. · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8491883

    Treatment of amyotrophic lateral sclerosis using umbilical derived cells

    Advanced Technologies and Regenerative Medicine, LLC · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8491884

    Virus clearance of neoplastic cells from mixed cellular compositions

    ONCOLYTICS BIOTECH INC. · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8491890

    Methods and compositions for inhibiting diseases of the central nervous system

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8492340

    Methods of treating depression and other related diseases

    Northwestern University · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8491893

    Oncofetal antigen/immature laminin receptor antibodies for diagnostic and clinical applications

    Quantum Immunologics, Inc. · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8492338

    Targeted therapeutic proteins

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8492399

    3-carboxypropyl-aminotetralin derivatives and related compounds as mu opioid receptor antagonists

    Theravance, Inc. · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8492373

    Bicyclic aryl and bicyclic heteroaryl substituted triazoles useful as Axl inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8491886

    Viruses for the treatment of cellular proliferative disorders

    ONCOLYTICS BIOTECH INC. · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8492337

    Targeted therapeutic proteins

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8492347

    Peptide for induction of immune tolerance as treatment for systemic lupus erythematosus

    The Regents of the University of California · Granted Tue Jul 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2033?

1,330 published patents in our USPTO index have expiration dates falling in calendar year 2033.