Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2033

Annual patent cliff calendar for 2033 — US pharmaceutical patents by expiration date.

Patents
1,330

Quick answer

1,330 indexed pharmaceutical patents have expiration dates in 2033. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8435575

    Use of gingerols for cancer patients suffering from nausea and emesis induced by chemotherapy

    Aphios Corporation · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 8435533

    Methods and compositions for vaccination comprising nucleic acid and/or polypeptide sequences of Chlamydia

    The Board of Regents of the University of Texas System · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 8435570

    Nitrite formulations and their use as nitric oxide prodrugs

    The Board of Regents of the University of Texas System · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 8435505

    Pharmaceutical compositions and methods for delivering such compositions

    Nektar Therapeutics · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 8440206

    Methods for producing an immune response to tuberculosis

    The United States of America as represented by the Department of Veteran Affairs · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 8440210

    Stabilized pharmaceutical product

    TAKEDA GMBH · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 8440229

    Hollow silica nanospheres and methods of making same

    The Regents of the University of California · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 8440621

    Analogs of ShK toxin and their uses in selective inhibition of Kv1.3 potassium channels

    The Regents of the University of California · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 8440689

    Fused heteroaromatic pyrrolidinones

    Takeda Pharmaceutical Company Limited · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 8440692

    Hydrophilic derivatives of 2-aryl-4-quinolones as anticancer agents

    China Medical University · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 8440813

    Antiviral nucleoside analogs

    BioCryst Pharmaceuticals, Inc. · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 8440202

    Induction of an immune response against dengue virus using the prime-boost approach

    United States of America as represented by the Secretary of the Air Force · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 8440460

    Methods for transdifferentiating cells

    The Board of Regents of the University of Texas System · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 8440652

    MST1 kinase inhibitors and methods of their use

    LEXICON PHARMACEUTICALS, INC. · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 8440636

    Micro-RNA family that modulates fibrosis and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 8440208

    Chlamydial antigens as reagents for diagnosis and treatment of chlamydial infection and disease

    The Board of Regents of the University of Texas System · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 8440832

    Heterocyclic modulators of cannabinoid receptors

    The Board of Regents of the University of Texas System · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 8440182

    Methods and compositions for treating phenylketonuria

    The Board of Regents of the University of Texas System · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 8440816

    Branched polymers

    Nektar Therapeutics · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 8440811

    DNA nanostructures that promote cell-cell interaction and use thereof

    Arizona Board of Regents, a Body Corporate acting for and on behalf of Arizona State University · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 8440707

    Antagonists of lysophosphatidic acid receptors

    AMIRA PHARMACEUTICALS, INC. · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 8440168

    Image-guided therapy of myocardial disease: composition, manufacturing and applications

    The Board of Regents of the University of Texas System · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 8440706

    Inhibitors of serine proteases

    Vertex Pharmaceuticals Incorporated · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 8440722

    Methods for concomitant administration of colchicine and a second active agent

    Takeda Pharmaceuticals U.S.A., Inc. · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 8440721

    Methods for concomitant administration of colchicine and a second active agent

    Takeda Pharmaceuticals U.S.A., Inc. · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 8440679

    Bicyclic compounds and their uses as dual c-SRC / JAK inhibitors

    Aurigene Discovery Technologies Limited · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 8440667

    Imidazopyrazine Syk inhibitors

    GILEAD CONNECTICUT, INC. · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 8440787

    Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom

    Nektar Therapeutics · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 8440687

    Oligomer-opioid agonist conjugates

    Nektar Therapeutics · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 8440739

    Dental composition and composite resin

    JGC Catalysts and Chemicals Ltd. · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 8440618

    Composition for the attachment of implants to collagen or other components of biological tissue

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 8440623

    Polymer stabilized neuropeptides

    Nektar Therapeutics · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 8440614

    Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein

    Aphios Corporation · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 8440432

    Tal effector-mediated DNA modification

    Regents of the University of Minnesota · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 8440431

    TAL effector-mediated DNA modification

    Regents of the University of Minnesota · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 8440415

    BORIS isoforms and methods of detecting and treating disease

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 8440411

    Differential gene expression in physiological and pathological angiogenesis

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 8440393

    Pro-angiogenic genes in ovarian tumor endothelial cell isolates

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 8440309

    Crosslinked polymers with the crosslinker as therapeutic for sustained release

    Covidien LP · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 8440205

    Streptococcal C5A peptidase vaccine

    Regents of the University of Minnesota · Granted Tue May 14 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 09 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. EP 2591003

    KREBSTHERAPIE MITTELS CLDN6-ZIELGERICHTETER ANTIKÖRPER IN VIVO

    GANYMED PHARMACEUTICALS AG [DE] · Granted Wed May 15 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue May 10 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 8445021

    Functionalized magnetic nanoparticles and methods of use thereof

    The Regents of the University of California · Granted Tue May 21 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 8444991

    Method of preparing an immunologically-active adjuvant-bound dried vaccine composition

    The Regents of the University of Colorado, a Body Corporate · Granted Tue May 21 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 8444612

    Self contained wound dressing apparatus

    Covidien LP · Granted Tue May 21 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 8445665

    Therapeutic compositions

    Alnylam Pharmaceuticals, Inc. · Granted Tue May 21 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 8445694

    Hydrazonopyrazole derivatives and their use as therapeutics

    Dermira (Canada), Inc. · Granted Tue May 21 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 8445714

    Cycloalkylmethylamines

    REVIVA PHARMACEUTICALS, INC. · Granted Tue May 21 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 8445696

    Synthetic methods for spiro-oxindole compounds

    Xenon Pharmaceuticals Inc. · Granted Tue May 21 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 16 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2033?

1,330 published patents in our USPTO index have expiration dates falling in calendar year 2033.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.