Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2031

Annual patent cliff calendar for 2031 — US pharmaceutical patents by expiration date.

Patents
902

Quick answer

902 indexed pharmaceutical patents have expiration dates in 2031. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8034384

    Method of increasing biocompatibility of medical device by generating nitric oxide

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 11 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 06 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. DE 102010014113

    Freisetzungsverfahren für Implantate

    ACINO AG [DE] · Granted Thu Oct 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8039661

    Thiophene-carboxamides useful as inhibitors of protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8039623

    Inhibitors of serine proteases, particularly HCV NS3-NS4A protease

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8039620

    Varenicline tosylate, an intermediate in the preparation process of varenicline L-tartrate

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8039627

    Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8039579

    Intermediates useful in the preparation of maleimide functionalized polymers

    Nektar Therapeutics · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8039489

    Guanidine-containing compounds useful as muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8039585

    Therapeutic administration of the scrambled anti-angiogenic peptide C16Y

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8039491

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8039500

    Fused heterocyclic compounds

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8039475

    Co-crystals and pharmaceutical compositions comprising the same

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8039001

    Therapeutic and prophylactic vaccine for the treatment and prevention of papillomavirus infection

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8038997

    Anti-marinobufagenin antibodies and methods for their use

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8039003

    Recombinant attenuated dengue viruses comprising a deletion in the 3′ untranslated region and additional attenuating mutations induced by chemical mutagenesis

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8039008

    Identification of residues critical for the function of the vibrio cholerae virulence regulator ToxT by scanning alanine mutagenesis

    The Board of Regents of the University of Texas System · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8039257

    Pre-transplant accomodated organs resistant to anti-donor immunity

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8039593

    Antibodies and immunotoxins that target human glycoprotein NMB

    The United States of America, as represented by the Secretary, Health and Human Services · Granted Tue Oct 18 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 13 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8044018

    Reagents and methods for smooth muscle therapies

    THE ARIZONA BOARD OF REGENTS · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8044054

    Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8043617

    Human antibodies to human IL-6 receptor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8044259

    Determining the capability of a test compound to affect solid tumor stem cells

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8044236

    Carboxilic acid derivatives

    Institute of Medicinal Molecular Design, Inc. · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8043623

    Immunogenic peptides for the treatment of prostate and breast cancer

    The Government of the United States of America as represented by the Secretary of the Deptartment of Health and Human Services · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8043820

    Diagnostic methods for the detection of risk of autistic spectrum disorder

    The Regents of the University of California · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8043853

    Postnatal gut neural crest stem cells

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8044026

    Composition for promoting cartilage formation or repair comprising a NELL gene product and method of treating cartilage-related conditions using such composition

    The Regents of the University of California · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8044045

    Indazole-carboxamide compounds as 5-HT4 receptor agonists

    Theravance, Inc. · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8044057

    Methods for suppressing an immune response or treating a proliferative disorder

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8044049

    Fused heterocyclic derivative and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8044093

    Pharmaceutical compositions comprising docetaxel and methods for preparation thereof

    Beijing Century Biocom Pharmaceutical Technology Co., Ltd. · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8044185

    Conformationally stabilized HIV envelope immunogens and triggering HIV-I envelope to reveal cryptic V3-loop epitopes

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8044187

    Human luteinizing hormone superagonists

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8044195

    Cross-linked glycopeptide-cephalosporin antibiotics

    Theravance, Inc. · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8043625

    Purified plasmodium and vaccine compositions

    Sanaria Inc. · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8044033

    Fluorocytidine derivatives and COX-2 inhibitors for the treatment of cancer

    The Board of Regents of the University of Texas System · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8044189

    Bacillus anthracis protective antigen nucleic acid sequences

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8043622

    Method of treating inflammatory lung disease with suppressors of CpG oligonucleotides

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Oct 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8049016

    Thiazole derivatives which inhibit stearoyl-CoA desaturase enzymes

    Xenon Pharmaceuticals Inc. · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8048432

    Polysaccharide-protein conjugate vaccines

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8048646

    NELL peptide expression systems and bone formation activity of NELL peptide

    The Regents of the University of California · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8048427

    Subgenomic replicons of the flavivirus dengue

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8048415

    Compositions and methods for promoting or inhibiting angiogenesis

    Northwestern University · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8048222

    Highly pure modafinil

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8048844

    Preventing airway mucus production by administration of EGF-R antagonists

    The Regents of the University of California · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8048889

    3,4-disubstituted coumarin and quinolone compounds

    XTL BIOPHARMACEUTICALS LTD. · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8048851

    Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response

    The Regents of the University of California · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8048906

    Optically pure and enriched isomers of chelating ligands and contrast agents

    Catalyst Medical · Granted Tue Nov 01 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 27 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2031?

902 published patents in our USPTO index have expiration dates falling in calendar year 2031.