Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2031

Annual patent cliff calendar for 2031 — US pharmaceutical patents by expiration date.

Patents
902

Quick answer

902 indexed pharmaceutical patents have expiration dates in 2031. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8013152

    Biphenyl compounds useful as muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8012739

    Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA synthetase pairs

    The Regents of the University of California · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8013015

    Small molecule inhibitors of ghrelin O-acyltransferase

    The Board of Regents of the University of Texas System · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8012965

    Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8012490

    Recombinant influenza viruses expressing tumor-associated antigens as antitumor agents

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8012476

    Molecules with extended half-lives, compositions and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8012730

    Specific lysis of staphylococcal pathogens by bacteriophage phi11 endolysin

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8012493

    Malaria vaccines

    The United States of America as represented by the Secretary of the Army · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8012699

    Recombinant antigens for diagnosis and prevention of murine typhus

    United States of America as represented by the Secretary of the Air Force · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8012946

    Anti-angiogenic methods and compositions

    Sangamo Biosciences, Inc. · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8012976

    Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP)

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8012955

    N-substituted-heterocycloalkyloxybenzamide compounds and methods of use

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8013005

    Dual-acting antihypertensive agents

    Theravance, Inc. · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8017155

    Methods for encapsulation of biomacromolecules in polymers

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8017578

    Orally active peptides that prevent cell damage and death

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8017617

    Amidine-containing compounds useful as muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8017636

    1,2,4-Oxadiazole benzoic acid compositions and their use in bioassays

    PTC THERAPEUTICS, INC. · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8017745

    Plasmodium falciparum antigens and methods of use

    United States of America as represented by the Secretary of the Air Force · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8017762

    Modified iRNA agents

    Alnylam Pharmaceuticals, Inc. · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8017781

    Azaindazoles useful as inhibitors of kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8017135

    Lipid-drug conjugates for local therapy of eye diseases

    The Regents of the University of California · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8017619

    Compositions useful as inhibitors of protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8017763

    Chemically modified oligonucleotides

    Alnylam Pharmaceuticals, Inc. · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8017783

    Biphenyl compounds useful as muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8017130

    Method of accelerated vaccination against Ebola viruses

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8017151

    Amphiphilic polymer-protein conjugates and methods of use thereof

    Board of Regents of the University of Nebraska by and behalf of the University of Nebraska Medical Center · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8017149

    Modified release preparations containing oxcarbazepine and derivatives thereof

    Supernus Pharmaceuticals, Inc. · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8017321

    Gefitinib sensitivity-related gene expression and products and methods related thereto

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Sep 13 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 08 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8022202

    Dihydrodiazepines useful as inhibitors of protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8022175

    Production of anti-peptide monoclonal antibodies to distinguish Exotic New Castle diseases viruses from vaccine strains of Newcastle disease virus

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8022041

    Prodrug of an ICE inhibitor

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8021831

    Taxane chemosensitivity prediction test

    The Board of Regents of the University of Texas System · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8021687

    Modified release compositions of milnacipran

    Collegium Pharmaceutical, Inc. · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8021673

    Proteins with repetitive Bacterial-Ig-like (Big) domains present in Leptospira species

    The Regents of the University of California · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8021644

    Methods for measuring rates of reverse cholesterol transport in vivo, as an index of anti-atherogenesis

    The Regents of the University of California · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8021646

    Compositions and methods for magnetic resonance imaging contrast agents

    Northwestern University · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8021671

    Pro-apoptotic bacterial vaccines to enhance cellular immune responses

    The United States of America as represented by the Department of Veteran Affairs · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8021874

    Very long chain polyunsaturated fatty acids, methods of production, and uses

    The Board of Regents of the University of Oklahoma · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8022040

    Hydroxyapatite-binding peptides for bone growth and inhibition

    The Regents of the University of California · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8022052

    Inhibition of PPAR gamma expression by specific osteogenic oxysterols

    The Regents of the University of California · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8022057

    MAPK/ERK kinase inhibitors

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8022094

    Carvedilol phosphate

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8022190

    Immuno-molecules containing viral proteins, compositions thereof and methods of using

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Sep 20 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 15 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8025887

    Avirulent, immunogenic flavivirus chimeras

    The United States of America as represtented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention · Granted Tue Sep 27 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8026360

    Substituted pyridazines as stearoyl-CoA desaturase inhibitors

    Xenon Pharmaceuticals Inc. · Granted Tue Sep 27 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8026234

    Polo-like kinase inhibitors

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 27 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8026263

    Methods for inhibiting neoproliferative changes in blood vessel walls

    The Regents of the University of California · Granted Tue Sep 27 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8026350

    Tumor suppressor gene, p28ING5

    The United States of America as represented by theDepartment of Health and Human Services · Granted Tue Sep 27 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 22 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2031?

902 published patents in our USPTO index have expiration dates falling in calendar year 2031.