Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2031

Annual patent cliff calendar for 2031 — US pharmaceutical patents by expiration date.

Patents
902

Quick answer

902 indexed pharmaceutical patents have expiration dates in 2031. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7998987

    Inhibitors of c-Met and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 16 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7999007

    Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same

    United Therapeutics Corporation · Granted Tue Aug 16 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7999074

    Bacteriocins and novel bacterial strains

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Aug 16 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7999079

    Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins

    The Regents of the University of California · Granted Tue Aug 16 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7999077

    IRTA2 antibodies and methods of use

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Aug 16 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7999113

    Modulators of cystic fibrosis transmembrane conductance regulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 16 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8003660

    Modulators of muscarinic receptors

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8003112

    Meningococcal and pneumococcal conjugate vaccine and method of using same

    THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8003091

    Pharmaceutical compositions comprising purified intact bacterial minicells

    EnGeneIC Molecular Delivery Pty Ltd · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8003103

    High affinity human antibodies to human IL-18 receptor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8001922

    Application of a coating on a medical device

    ATRIUM MEDICAL CORPORATION · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8003406

    Methods for detecting attention-deficit/hyperactivity disorder

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8003685

    Thiophene analogues for the treatment or prevention of flavivirus infections

    Vertex Pharmaceuticals (Canada) Incorporated · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8003619

    Method of stimulating an immune response and inhibiting expression of a gene using an oligonucleotide

    Alnylam Pharmaceuticals, Inc. · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8003785

    Halo-substituted pyrimidodiazepines

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8003755

    Hydrochloride salts of a glycopeptide phosphonate derivative

    Theravance, Inc. · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8003742

    Polymer derivatives with proximal reactive groups

    Nektar Therapeutics · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8003126

    Stable tablet formulation

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8003693

    Modulation of anxiety through blockade of anandamide hydrolysis

    The Regents of the University of California · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8003754

    Paralytic peptide for use as a insecticide

    Soricimed Biopharma Inc. · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8003692

    Methods and compositions to inhibit edema factor and adenylyl cyclase

    The Board of Regents of the University of Texas System · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8003764

    Folliculin-specific antibodies and methods of detection

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8003664

    Indazole-carboxamide compounds

    Theravance, Inc. · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8003622

    Peptide biosynthesis and pain therapy

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8003629

    21-substituted progesterone derivatives as new antiprogestational agents

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 23 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 2011206613

    METHOD AND APPLICATION OF UNSYMMETRICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT

    WIEHE ARNO [DE] · Granted Thu Aug 25 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 20 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8008278

    Diarylmethyl and related compounds

    Theravance, Inc. · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8008308

    Phosphonate compounds

    The Regents of the University of California · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8007804

    Complement receptor 2 targeted complement modulators

    The Regents of the University of Colorado · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8007774

    Matrix composed of a naturally-occurring protein backbone cross linked by a synthetic polymer and methods of generating and using same

    REGENTIS BIOMATERIALS LTD. · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8007778

    Use of calcium binding proteins to improve cardiac contractile function

    The Regents of the University of California · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8007787

    Human cystathionine β-synthase variants and methods of production thereof

    The Regents of the University of Colorado · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8008353

    Methods for modulating macrophage proliferation using polyamine analogs

    The Regents of the University of California · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8008435

    Polymer stabilized neuropeptides

    Nektar Therapeutics · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8008501

    Quinoline compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8008332

    Substituted indazoles as glucokinase activators

    Takeda San Diego, Inc. · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8008266

    Methods of treating cancer using immunostimulatory oligonucleotides

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8008323

    Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases

    ACADIA Pharmaceuticals Inc. · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8008525

    Receptor function regulating agent

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8008510

    Metalloprotein inhibitors

    The Regents of the University of California · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8007853

    Vitamin/mineral composition with DHA

    Xanodyne Pharmaceuticals, Inc. · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8008316

    Azonafide derived tumor and cancer targeting compounds

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8008021

    N-terminal truncation of cardiac troponin subunits and their roles in cardiovascular disease

    Evanston Northwestern Healthcare · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8008038

    Methods for determining oxygen concentration with protoporphyrin IX

    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM · Granted Tue Aug 30 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8012976

    Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP)

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8013015

    Small molecule inhibitors of ghrelin O-acyltransferase

    The Board of Regents of the University of Texas System · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8012965

    Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8012490

    Recombinant influenza viruses expressing tumor-associated antigens as antitumor agents

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Sep 06 2011 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 01 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2031?

902 published patents in our USPTO index have expiration dates falling in calendar year 2031.