Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2028

Annual patent cliff calendar for 2028 — US pharmaceutical patents by expiration date.

Patents
624

Quick answer

624 indexed pharmaceutical patents have expiration dates in 2028. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7381748

    Compounds and related methods for inhibition of gamma-aminobutyric acid aminotransferase

    Northwestern University · Granted Tue Jun 03 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7381827

    Processes and intermediates

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 03 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7381404

    Treatment for dry macular degeneration

    The Regents of the University of California · Granted Tue Jun 03 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7381699

    Reagents and methods for smooth muscle therapies

    THE ARIZONA BOARD OF REGENTS · Granted Tue Jun 03 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7381825

    Histone deacetylase inhibitors

    Takeda San Diego, Inc. · Granted Tue Jun 03 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7381744

    Method of treating osteoporosis comprising vacuolar-type (H+)-ATPase-inhibiting compounds

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Jun 03 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7381405

    Methods of preparing lymphocytes that express interleukin-2 and their use in the treatment of cancer

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Jun 03 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7381408

    Methods for chemically synthesizing immunoglobulin chimeric proteins

    Syntonix Pharmaceuticals, Inc. · Granted Tue Jun 03 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. EP 1926473

    ANTIMIKROBIELLE ZUBEREITUNGEN MIT EINEM IN LIPOSOMEN VERKAPSELTEN GEHALT AN OCTENIDINDIHYDROCHLORID

    AIR LIQUIDE SANTE INT [FR] · Granted Wed Jun 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7384978

    Compounds and methods for delivery of prostacyclin analogs

    United Therapeutics Corporation · Granted Tue Jun 10 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7384909

    Anti-viral treatment methods using phosphatidylethanolamine-binding peptides linked to anti-viral agents

    The Board of Regents of the University of Texas System · Granted Tue Jun 10 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7384921

    Polymorphic forms of 6-11 bicyclic ketolide derivatives

    Enanta Pharmaceuticals, Inc. · Granted Tue Jun 10 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7384623

    High energy phototherapeutic agents

    Provectus Pharmatech, Inc. · Granted Tue Jun 10 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7388079

    Delivery of pharmaceutical agents via the human insulin receptor

    The Regents of the University of California · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7388089

    Anti-arthropod vector vaccines method of selecting and uses thereof

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7388074

    Mutant plasminogen activator-inhibitor type 1 (PAI-1) and uses thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7387896

    MicroRNA vectors

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7388071

    Composition and method for inducing and enhancing a telomerase reverse transcriptase-reactive cytotoxic T lymphocyte response

    The Regents of the University of California · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7388002

    Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases

    BioCryst Pharmaceuticals, Inc. · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7388032

    Sustained release compositions, process for producing the same and utilization thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7387881

    Detection and treatment of cancers of the liver

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7388017

    Inhibitors of serine proteases, particularly hepatitis C virus NS3 protease

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7388088

    High affinity human antibodies to tumor antigens

    The Regents of the University of California · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7387792

    Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration

    Collegium Pharmaceutical, Inc. · Granted Tue Jun 17 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. AU 2007332640

    Powder formulation for valganciclovir

    HOFFMANN LA ROCHE [DE] · Granted Thu Jun 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7390625

    Apoptosis-associated protein and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 24 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7390646

    Bacterial vectors and methods of use thereof

    The Regents of the University of California · Granted Tue Jun 24 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7390808

    Inhibitors of GSK-3 and crystal structures of GSK-3β protein and protein complexes

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 24 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7390510

    Preparation of hypericin bonded with poly-N-vinylamides

    SANOCHEMIA PHARMAZEUTIKA AG · Granted Tue Jun 24 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7390668

    Intracorporeal medicaments for photodynamic treatment of disease

    Provectus Pharmatech, Inc. · Granted Tue Jun 24 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7390807

    Crystal forms of lamotrigine and processes for their preparations

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jun 24 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7390815

    Pyrazole compounds useful as protein kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 24 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7390813

    Pyridylpiperazines and aminonicotinamides and their use as therapeutic agents

    Xenon Pharmaceuticals Inc. · Granted Tue Jun 24 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. CA 2673419

    COMPOSITION PHARMACEUTIQUE

    GENERICS UK LTD [GB] · Granted Thu Jun 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. CA 2673418

    COMPOSE ET COMPOSITION PHARMACEUTIQUES

    ALPHAPHARM PTY LTD [AU] · Granted Thu Jun 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. CA 2670932

    DETECTION DU DETACHEMENT D'UN AGENT DE CONTRASTE IMMOBILISE DANS DES APPLICATIONS D'IMAGERIE MEDICALE

    BRACCO INT BV [NL] · Granted Thu Jun 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7393994

    Transgenic mouse model for neurodegenerative diseases

    The Regents of the University of California · Granted Tue Jul 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 26 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 7393544

    Dispersion for pulmonary delivery of a bioactive agent

    Nektar Therapeutics · Granted Tue Jul 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 26 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7393842

    Pyrazole analogs acting on cannabinoid receptors

    UNIVERSITY OF CONNECTICUT · Granted Tue Jul 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 26 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7393855

    2,2-bis-(hydroxymethyl)cyclopropylidenemethyl-purines and pyrimidines as antiviral agents

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 26 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7393833

    Chimeric proteins with phosphatidylserine binding domains

    The Board of Regents of the University of Oklahoma · Granted Tue Jul 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 26 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. EP 1938801

    Nanoemulsion

    BIOFRONTERA BIOSCIENCE GMBH [DE] · Granted Wed Jul 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Jun 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 7396839

    Crystalline forms of gatifloxacin

    Teva Pharmaceuticals USA, Inc. · Granted Tue Jul 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7396816

    Low-molecular weight peptides inhibiting ion channel activity

    Pharmadesign, Inc. · Granted Tue Jul 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7396848

    Neurotrophin production/secretion promoting agent

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7396933

    Quinolinone-carboxamide compounds

    Theravance, Inc. · Granted Tue Jul 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7396841

    Injections

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7396927

    Process for preparation of rosuvastatin calcium

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jul 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2028?

624 published patents in our USPTO index have expiration dates falling in calendar year 2028.