Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2028

Annual patent cliff calendar for 2028 — US pharmaceutical patents by expiration date.

Patents
624

Quick answer

624 indexed pharmaceutical patents have expiration dates in 2028. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7371821

    Cloning and expression of the full length 110 kDa antigen of Orientia tsutsugamushi to be used as a vaccine component against scrub typhus

    United States of America as represented by the Secretary of the Air Force · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7371403

    Wound dressing and method for controlling severe, life-threatening bleeding

    Providence Health System—Oregon · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7371719

    Self-assembly of peptide-amphiphile nanofibers under physiological conditions

    Northwestern University · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7371772

    Bicyclic compound, production and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7371841

    Methods of modulating cold sensory perception

    The Regents of the University of California · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7371575

    Process for ex vivo formation of mammalian bone and uses thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7371571

    Recombinant mycobacteria overexpressing D-alanine ligase gene and uses therefore

    BOARD OF REGENTS UNIVERSITY OF NEBRASKA-LINCOLN · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7371372

    Compositions comprising IMPDH inhibitors and uses thereof for treating HCV infection

    Vertex Pharmaceuticals Incorporated · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7371385

    Method of treating immune pathologies with low dose estrogen

    Government of the United states of America dba The Department of Veterans Affairs · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7371572

    Mouse titers after two immunizations with VLPs alone

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7371392

    Cd40 ligand adjuvant for respiratory syncytial virus

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7371225

    Method for convection enhanced delivery of therapeutic agents

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue May 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7374757

    Modified chimeric polypeptides with improved pharmacokinetic properties

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7374931

    Vaccine against staphylococcus intoxication

    The United States of America as represented by the Secretary of the Army · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7375181

    Process for purifying glycopeptide phosphonate derivatives

    Theravance, Inc. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7374752

    Reovirus for the treatment of cellular proliferative disorders

    ONCOLYTICS BIOTECH INC. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7375114

    Quinolinone-carboxamide compounds as 5-HT4 receptor agonists

    Theravance, Inc. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7374936

    Method and means for site directed therapy

    Actinium Phamaceuticals, Inc. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7375185

    Cardiac myosin light chain kinase polypeptide, encoding nucleic acid, and methods of use

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7375092

    Lunasin peptides

    The Regents of the University of California · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7375079

    Previns as specific inhibitors and therapeutic agents for botulinum toxin B and tetanus neurotoxins

    The United States of America as represented by the Secretary of the Army · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7375074

    Body weight gain inhibitor

    Takeda Chemical Industries Ltd. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7374754

    Use of placental alkaline phosphatase to promote skin cell proliferation

    Essential Skincare, LLC · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7375086

    Modulators of Nod2 signaling

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7374932

    Human kinases and polynucleotides encoding the same, and uses thereof

    LEXICON PHARMACEUTICALS, INC. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7374770

    Topical composition for follicular delivery of an ornithine decarboxylase inhibitor

    SkinMedica, Inc. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7374758

    Modified chimeric polypeptides with improved pharmacokinetic properties and methods of using thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7374776

    Bone-filling composition for stimulating bone-forming and bone-consolidation comprising calcium sulfate and viscous biopolymers

    REGENBiotech, Inc. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7374910

    DNA encoding galanin receptor activating peptide

    Takeda Pharmaceutical Company Limited · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7374872

    CC chemokine receptor 5 DNA, new animal models and therapeutic agents for HIV infection

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7374756

    Specific binding agents for KSHV vIL-6 that neutralize a biological activity

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7375228

    Histone deacetylase inhibitors

    Takeda San Diego, Inc. · Granted Tue May 20 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7378553

    Isolated atomoxetine impurity, processes for the preparation of atomoxetine impurities and their use as reference standards

    Teva Pharmaceutical Fine Chemicals S.R.L. · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7378386

    Anti-viral treatment methods using phosphatidylethanolamine-binding peptide derivatives

    The Board of Regents of the University of Texas System · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 7378093

    Broadly cross-reactive neutralizing antibodies against Human Immunodeficiency Virus selected by Env-CD4-co-receptor complexes

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 7378403

    Akt inhibitors, pharmaceutical compositions, and uses thereof

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7378097

    Use of penetration enhancers and barrier disruption methods to enhance the immune response of antigen and adjuvant

    The United States of America as represented by the Secretary of the Army · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 7378422

    Inhibitors of serine proteases, particularly HCV NS3-NS4A protease

    Vertex Pharmaceuticals Incorporated · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7378277

    Methods and compositions for transforming dendritic cells and activating T cells

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7378496

    hKCa3/KCNN3 small conductance calcium activated potassium channel: a diagnostic marker and therapeutic target

    The Regents of the University of California · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7378469

    Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)

    Nektar Therapeutics AL, Corporation · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 7378276

    Method of inducing memory B cell development and terminal differentiation

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 7378257

    Bacterial superantigen vaccines

    The United States of America as represented by the Secretary of the Army · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7378108

    Percutaneous absorption preparation of compound having angiotensin II antagonistic activity

    Takeda Pharmaceutical Company Limited · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7378273

    Expression vectors

    Gala Design, Inc. · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7378251

    Methods of identifying compounds that modulate IL-4 receptor-mediated IgE synthesis utilizing a thioredoxin-like 32 kDa protein

    Rigel Pharmaceuticals, Inc. · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7378095

    Methods of treating type I diabetes by blocking VEGF-mediated activity

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7378552

    Monoamine re-uptake inhibitors and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2028?

624 published patents in our USPTO index have expiration dates falling in calendar year 2028.