Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2028

Annual patent cliff calendar for 2028 — US pharmaceutical patents by expiration date.

Patents
624

Quick answer

624 indexed pharmaceutical patents have expiration dates in 2028. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7351717

    Substituted pyrrolidine and related compounds

    Theravance, Inc. · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7351704

    Indazole-carboxamide compounds as 5-HT4 receptor agonists

    Theravance, Inc. · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7351791

    Intermediate for preparing glycopeptide derivatives

    Theravance, Inc. · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7351691

    Glycopeptide phosphonate derivatives

    Theravance, Inc. · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7351411

    Methods of treating anemia by inhibition of vascular endothelial growth factor (VEGF)

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7351707

    Spiroazacyclic compounds as monoamine receptor modulators

    ACADIA Pharmaceuticals Inc. · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7351435

    Deglycosylated ricin toxin a-chain vaccine

    The United States of America as represented by the Secretary of the Army · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7351702

    Caspase inhibitors and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7351830

    Pancratistatin cyclic phosphate prodrugs and phenpanstatin cyclic phosphate prodrugs

    ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7354582

    Use of VEGF antagonists for the treatment of malignant gliomas

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7354904

    Bacteriocin inducer peptides

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7354761

    Methods and composition for the production of orthogonal tRNA-aminoacyltRNA synthetase pairs

    The Regents of the University of California · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7354711

    Methods for inhibiting immunostimulatory DNA associated responses

    The Department of Veterans Affairs, as represented by the Secretary of United States of America · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7354580

    Method of administering and using VEGF inhibitors for the treatment of human cancer

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7354579

    Method of treating cancer with a VEGF antagonist and an anti-proliferative agent

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7354578

    Method of tumor regression with VEGF inhibitors

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7354576

    Methods of treating diseases caused by deficiencies of recombinant α-L-iduronidase

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7355079

    Thyronamine derivatives and analogs and methods of use thereof

    The Regents of the University of California · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7354581

    Therapeutic combination of a VEGF antagonist and anti-hypertensive agent

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7354909

    Method for rapid generation of mature dendritic cells

    UNITED STATES OF AMERICA, AS REPRESENTED BY SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7355012

    Mutated anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cells

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7355047

    Substituted quinolone carboxylic acids, their derivatives, site of action, and uses thereof

    The Regents of the University of California · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7354900

    Treatment and inhibition of ocular infections and wounds by CAP37 and CAP37 peptides

    The Board of Regents of the University of Oklahoma · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7354894

    Preventing airway mucus production by administration of EGF-R antagonists

    The Regents of the University of California · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7354912

    Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced GI toxicity

    The Board of Regents of the University of Texas System · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7353829

    Methods and apparatus for multi-photon photo-activation of therapeutic agents

    Provectus Devicetech, Inc. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7355046

    Biphenyl derivatives

    Theravance, Inc. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7355018

    Modified IGF1 polypeptides with increased stability and potency

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7355078

    Processes for the preparation of tomoxetine

    Teva Pharmaceutical Fine Chemicals S.R.L. · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7355001

    Organic anion transport protein TCH229

    Takeda Pharmaceutical Company Limited · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7354939

    Pyrrole inhibitors of ERK protein kinase, synthesis thereof and intermediates thereto

    Vertex Pharmaceuticals Incorporated · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7354936

    2-phenylpyran-4-one derivatives

    ALMIRALL, LLC · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7354928

    Small molecule inhibitors targeted at Bcl-2

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7354919

    Isoxazole compositions useful as inhibitors of ERK

    Vertex Pharmaceuticals Incorporated · Granted Tue Apr 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. DE 102006048130

    Transdermales therapeutisches System mit zweiphasigem Freisetzungsprofil

    AXXONIS PHARMA AG [DE] · Granted Thu Apr 10 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 7358222

    Preventing airway mucus production by administration of EGF-R antagonists

    The Regents of the University of California · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7358258

    Prodrugs of an ERK protein kinase inhibitor

    Vertex Pharmaceuticals Incorporated · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 7358086

    Mammalian two-hybrid system for screening for modulators of the accumulation of metabolic products

    The Regents of the University of California · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7358226

    Ultrasonic concentration of drug delivery capsules

    The Regents of the University of California · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7357945

    Stable pharmaceutical formulation of paroxetine hydrochloride and a process for preparation thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7358273

    Inhibitors of caspases

    Vertex Pharmaceuticals Incorporated · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 7358390

    Polymorphic forms of nateglinide

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 7358360

    Risedronate sodium having a very low content of iron

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7358377

    Schweinfurthin analogues

    The United States of America · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7358364

    Substituted carboxylic acids

    The Institute for Pharmaceutical Discovery, LLC · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7358259

    HCV inhibitors and methods of using them

    Rigel Pharmaceuticals, Inc. · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7358247

    Mycophenolate mofetil impurity

    TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7358248

    Substituted amino carboxylic acids

    The Institute for Pharmaceutical Discovery, LLC · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2028?

624 published patents in our USPTO index have expiration dates falling in calendar year 2028.