Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2028

Annual patent cliff calendar for 2028 — US pharmaceutical patents by expiration date.

Patents
624

Quick answer

624 indexed pharmaceutical patents have expiration dates in 2028. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7335383

    Generation of nitric oxide in vivo from nitrite, nitrate or nitrosothiols endogenous in blood

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7338758

    Compositions and methods for the identification, assessment, prevention and therapy of human cancers

    The Board of Regents of the University of Texas System · Granted Tue Mar 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7338961

    Sphingosine kinase inhibitors

    Apogee Biotechnology Corporation · Granted Tue Mar 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7338652

    Methods for positron emission imaging with radiolabeled halogenated xanthenes diagnostic agents

    Provectus Pharmatech, Inc. · Granted Tue Mar 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7339064

    Benzimidazole compound crystal

    Takeda Pharmaceutical Company Limited · Granted Tue Mar 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7338798

    System and method for forming a cardiac muscle construct

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7339037

    Glycosylation-resistant cyanovirins and related conjugates, compositions, nucleic acids, vectors, host cells, methods of production and methods of using nonglycosylated cyanovirins

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Mar 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7338807

    Screening assays for compounds that cause apoptosis

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Mar 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7339023

    Partial peptide mimetics and methods

    Regents of the University of Minnesota · Granted Tue Mar 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7341871

    Nucleotide sequences for gene regulation and methods of use thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7341993

    Cross-linked glycopeptide—cephalosporin antibiotics

    Theravance, Inc. · Granted Tue Mar 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7342105

    Antibody and use thereof

    Takeda Chemical Industries Ltd. · Granted Tue Mar 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7342101

    Compositions and methods comprising a protective antigen of Coccidiodes immitis

    THE UNIVERSTY OF TEXAS SYSTEM,BOARD OF REGENTS · Granted Tue Mar 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7342120

    Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Mar 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7341726

    Modified HCV peptide immunogens

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7341709

    Compositions for labeling β-amyloid plaques and neurofibrillary tangles

    The Regents of the University of California · Granted Tue Mar 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7342046

    Gossypol co-crystals and the use thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 2008063603

    ULTRASOUND CONTRAST AGENTS AND METHODS OF MAKING AND USING THEM

    BRACCO INT BV [NL] · Granted Thu Mar 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Mar 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7344711

    Use of adenoviruses mutated in the VA genes for cancer treatment

    ONCOLYTICS BIOTECH INC. · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7345060

    Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity

    Theravance, Inc. · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7346387

    Methods for improved selectivity in photo-activation and detection of molecular diagnostic agents

    Provectus Devicetech, Inc. · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7345175

    Biphenyl derivatives

    Theravance, Inc. · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7344722

    Cold-adapted influenza virus

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7345030

    Use of n-acetyl-d-aminoglycosamine in treatment of organ lesions related to toxicosis of drugs or chemicals

    Third Military Medical University, Chinese People's Liberation Army, P.R. of China · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7344829

    Methods for detecting the efficacy of anticancer treatments

    The Board of Regents of the University of Texas System · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7344724

    UspA1 and UspA2 antigens of Moraxella catarrhalis

    The Board of Regents of the University of Texas System · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7344712

    Urinary tract tissue graft compositions and methods for producing same

    The Board of Regents of the University of Oklahoma · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7344703

    Mycobacterial sulfation pathway proteins and methods of use thereof

    The Regents of the University of California · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7344531

    Thermal surgical procedures and compositions

    Regents of the University of Minnesota · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7344530

    Thermal surgical procedures and compositions

    Regents of the University of Minnesota · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7345054

    Heterocyclic inhibitors of ERK2 and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7348004

    Immunoglobulin chimeric monomer-dimer hybrids

    Syntonix Pharmaceuticals, Inc. · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7347987

    Inhibition of reactive oxygen species and protection of mammalian cells

    The Regents of the University of Oklahoma · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7348330

    1-azabicyclo [2,2,2] octan-3-one derivatives

    APREA AB · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 7348314

    Compositions and methods for inhibiting viral replication

    Alnylam Europe AG · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 7348429

    Process for purifying N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide(zaleplon) and crystalline forms of zaleplon accessible with the process

    TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7348359

    Retinoid X receptor modulators

    Ligand Pharmaceuticals Incorporated · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 7348319

    Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7348153

    Method for identifying and designing immunogenic peptides

    The Board of Regents of the University of Texas System · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7348335

    Compositions useful as inhibitors of JAK and other protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7348324

    Cyclic amine compounds as CCR5 antagonists

    Takeda Pharmaceutical Company Limited · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 2008076803

    MICROBICIDAL PREPARATIONS BASED ON 1,2-BENZISOTHIAZOLIN-3-ONEMICROBICIDAL PREPARATIONS BASED ON 1,2-BENZISOTHIAZOLIN-3-ONE

    AIR LIQUIDE SANTE INT [FR] · Granted Thu Mar 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Mar 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 7351691

    Glycopeptide phosphonate derivatives

    Theravance, Inc. · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7351403

    Sunscreen reagents from unsaturated waxes and triglycerides

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7351827

    Substituted oxetanes, method of making, and method of use thereof

    UNIVERSITY OF CONNECTICUT · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7351739

    Bioactive compounds and methods of uses thereof

    Regents of the University of Minnesota · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7351718

    Substituted pyrrolidine and related compounds

    Theravance, Inc. · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7351717

    Substituted pyrrolidine and related compounds

    Theravance, Inc. · Granted Tue Apr 01 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2028?

624 published patents in our USPTO index have expiration dates falling in calendar year 2028.