Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2028

Annual patent cliff calendar for 2028 — US pharmaceutical patents by expiration date.

Patents
624

Quick answer

624 indexed pharmaceutical patents have expiration dates in 2028. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7329652

    Diaminotriazole compounds useful as protein kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7329671

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7329511

    Nucleic acid encoding GAD65

    The Regents of the University of California · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7329680

    Heterocycle substituted carboxylic acids

    The Institute for Pharmaceutical Discovery, LLC · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7329502

    ZAP-70 expression as a marker for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7329752

    Carbamate compounds as 5-HT4 receptor agonists

    Theravance, Inc. · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7329401

    Cyclooxygenase-2 selective agents useful as imaging probes and related methods

    The Regents of the University of California · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7329642

    β-2-glycoprotein is an inhibitor of angiogenesis

    The Board of Regents of the University of Texas System · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7329759

    Illudin analogs useful as antitumor agents

    The Regents of the University of California · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7329672

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 12 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. AU 2007283667

    Genes and proteins of Brachyspira hyodysenteriae and uses thereof

    SPIROGENE PTY LTD [DE] · Granted Thu Feb 14 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 09 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7332471

    Cross-linked glycopeptide-cephalosporin antibiotics

    Theravance, Inc. · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7332170

    Classical swine fever virus virulence determinant and a novel classical swine fever vaccine

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7331920

    Glycopeptide antibiotics, combinational libraries of glycopeptide antibiotics and methods of producing same

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7332159

    Method and composition for inhibiting reperfusion injury in the brain

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7332172

    Transformed bacteria producing CS6 antigens as vaccines

    The United States of America as represented by the Secretary of the Army · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7332321

    Viral fibers

    The Board of Regents of the University of Texas System · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7332469

    Intrapleural single-chain urokinase alone or complexed to its soluble receptor protects against pleural adhesions

    The Board of Regents of the University of Texas System · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7332281

    Therapeutic targets in cancer

    Sagres Discovery, Inc. · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7332287

    Methods and compositions for diagnosing breast cancer

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7332298

    Nucleic acids encoding multimeric proteins of TNF superfamily ligands

    The Regents of the University of California · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7332590

    Molecular characteristics of non-small cell lung cancer

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7332470

    Methods and compositions for treating ocular disease

    The Regents of the University of California · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7332472

    Cyclosporine analogue mixtures and their use as immunomodulating agents

    Isotechnika, Inc. · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7332484

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7332612

    Amorphous and crystalline forms of losartan potassium and process for their preparation

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7332602

    Pyridyl substituted heterocycles useful for treating or preventing HCV infection

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7332527

    Cross-linked ionic core micelles

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7332224

    Cleaning article containing hydrophilic polymers

    ReGenesis Group · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7332645

    IL-21 as a regulator of immunoglobin production

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7332585

    Bispecific single chain Fv antibody molecules and methods of use thereof

    The Regents of the California University · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7335356

    Monoclonal antibodies and complementarity-determining regions binding to Ebola glycoprotein

    The United States of America as represented by the Secretary of the Army · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7335689

    Dihydroxyl compounds and compositions for cholesterol management and related uses

    Esperion Therapeutics, Inc. · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7335772

    1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates

    TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 7335383

    Generation of nitric oxide in vivo from nitrite, nitrate or nitrosothiols endogenous in blood

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 7335477

    Truncated recombinant major outer membrane protein antigen (r56) of Orientia tsutsugamushi strains Karp, Kato and Gilliam and its use in antibody based detection assays and vaccines

    United States of America as represented by the Secretary of the Air Force · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7335679

    Wortmannin analogs and methods of using same

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 7335382

    Compositions and methods for the treatment and prevention of cancer

    Northwestern University · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7335499

    tRNA synthetase

    Replidyne, Inc. · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7335658

    Pyridazine derivatives and their use as therapeutic agents

    Xenon Pharmaceuticals Inc. · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7335681

    Amino ceramide-like compounds and therapeutic methods of use

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 7335646

    Compositions and methods for regulated protein expression in gut

    ENGENE, INC. · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 7335744

    Prostate cancer specific internalizing human antibodies

    The Regents of the California University · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7335640

    Administration of hypocretin-1 for treatment of narcolepsy

    The Regents of the University of California · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7335662

    Substituted tricyclic compounds as protein kinase inhibitors

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7335685

    Crystals of ladostigil tartrate, methods of production and pharmaceutical compositions thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7335749

    Tumor suppressor gene, p47Ing3

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7335773

    Intermediates for imidazonaphthyridines

    Graceway Pharmaceuticals. LLC · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2028?

624 published patents in our USPTO index have expiration dates falling in calendar year 2028.