Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2028

Annual patent cliff calendar for 2028 — US pharmaceutical patents by expiration date.

Patents
624

Quick answer

624 indexed pharmaceutical patents have expiration dates in 2028. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7459458

    Polymorph of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto

    Neurocrine Biosciences, Inc. · Granted Tue Dec 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7459601

    Human α synuclein expressing transgenic mice

    The Regents of the University of California · Granted Tue Dec 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7459462

    Fredericamycin derivatives

    Biofrontera Discovery GmbH · Granted Tue Dec 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7459536

    HGF-SF monoclonal antibody combinations

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7459453

    Pyridazin-3(2H)-one derivatives as PDE4 inhibitors

    Laboratories Almirall, S.A. · Granted Tue Dec 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7459439

    Granulysin peptides and methods of use thereof

    The Regents of the University of California · Granted Tue Dec 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7459156

    Antibodies that mimic actions of neurotrophins

    The Regents of the University of California · Granted Tue Dec 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7462612

    Pyridine inhibitors of ERK2 and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7462743

    Polymorphs of memantine hydrochloride

    Teva Pharmaceutical Fine Chemicals S.R.L. · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7462737

    Pregabalin free of isobutylglutaric acid and a process for preparation thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7462635

    Thiazole and oxazole VDAC regulator

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7462609

    Narcistatin prodrugs

    THE ARIZONA BOARD OF REGENTS · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7462625

    Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7462356

    Chimeric papillomavirus-like particles

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7462691

    Mouse prostate stem cell antigen and uses thereof

    The Regents of the University of California · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7462603

    Preparation of stable formulations of lipid-nucleic acid complexes for efficient in vivo delivery

    The Regents of the University of California · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7462345

    Radionuclide labeling of vitamin B12 and coenzymes thereof

    Regents of the University of Minnesota · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7462628

    Preventives/remedies for urinary disturbance

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7465748

    Amide derivative

    Rational Drug Design Laboratories · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7465716

    Targeted drug delivery with a hyaluronan ligand

    The Regents of the University of California · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7465715

    Method for treatment of multiple sclerosis

    CAN-FITE BIOPHARMA LTD. · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7465449

    Anti-αvβ6 antibodies

    The Regents of the University of California · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7465466

    Compositions and methods for prostate and kidney health and disorders, an herbal preparation

    Integrated Chinese Medicine Holdings Ltd. · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7465784

    Antimicrobial peptides and methods of identifying the same

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7465794

    Polynucleotides encoding recombinant respiratory syncytial viruses expressing immune modulatory molecules

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7465815

    Cannabinoid receptor modulator

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7465738

    Compounds useful as promoters of SMN2

    Vertex Pharmaceuticals Incorporated · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7465831

    Levalbuterol hydrochloride Polymorph A

    Teva Pharmaceutical Fine Chemicals S.R.L. · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7465825

    Phenyl substituted carboxylic acids

    The Institute for Pharmaceutical Discovery, LLC · Granted Tue Dec 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7468352

    Mutated anthrax toxin protective antigen proteins that specifically target cells containing high amounts of cell-surface metalloproteinases or plasminogen activator receptors

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Dec 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7468379

    Inhibition of osteolytic lesions by SRC kinase inhibitors

    The Board of Regents of the University of Texas System · Granted Tue Dec 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7468426

    Oncoprotein protein kinase antibody kit

    The Regents of the University of California · Granted Tue Dec 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7468420

    Process for purifying glycopeptide phosphonate derivatives

    Theravance, Inc. · Granted Tue Dec 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7468432

    Cobalamin conjugates useful as antitumor agents

    Regents of the University of Minnesota · Granted Tue Dec 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 7468444

    Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Dec 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 7468435

    Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxide release and related compounds, compositions comprising same and methods of using same

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Dec 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7468419

    Cyclosporin derivatives for the treatment of immune disorders

    Enanta Pharmaceuticals, Inc. · Granted Tue Dec 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 7468394

    Sterile pharmaceutical composition and process for a solution of propofol emulsion having microbial growth retardation

    Amphastar Pharmaceuticals, Inc. · Granted Tue Dec 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7470431

    Use of neurotoxin therapy for treatment of urological-neurological disorders associated with prostate cancer

    The Regents of the University of Colorado · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7470420

    Optical determination of glucose utilizing boronic acid adducts

    The Regents of the University of California · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7470430

    Modifications of HIV, ENV, GAG, and POL enhance immunogenicity for genetic immunization

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 7470659

    Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM)

    The Regents of the University of California · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 7470775

    Anti-CD30 stalk and anti-CD30 antibodies suitable for use in immunotoxins

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7470660

    Treatment for dark adaptation

    The Regents of the University of California · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7470790

    Heteroaromatic selective inhibitors of neuronal nitric oxide synthase

    Northwestern University · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7470776

    Glycosulfopeptide inhibitors of leukocyte rolling and methods of use thereof

    The Board of Regents of the University of Oklahoma · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7470700

    Dipeptidyl peptidase inhibitors

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7470506

    Fitness assay and associated methods

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Dec 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2028?

624 published patents in our USPTO index have expiration dates falling in calendar year 2028.