Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2028

Annual patent cliff calendar for 2028 — US pharmaceutical patents by expiration date.

Patents
624

Quick answer

624 indexed pharmaceutical patents have expiration dates in 2028. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7446108

    Tri-and tetraaza-acenaphthylen derivatives as CRF receptor antagonists

    Neurocrine, Inc. · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7446112

    Modulators of muscarinic receptors

    Vertex Pharmaceuticals Incorporated · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7445890

    Ucp-2 promoter and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7446185

    Her2/neu target antigen and use of same to stimulate an immune response

    The Regents of the University of California · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7445794

    Methods for treating human proliferative diseases, with a combination of fatty acid metabolism inhibitors and glycolytic inhibitors

    The Regents of the University of Colorado · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7449190

    Assays for assembly of Ebola virus nucleocapsids

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7449557

    Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy

    University of Connecticut Health Center · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7449570

    Use of nucleoside compounds for nonsense suppression and the treatment of genetic diseases

    PTC THERAPEUTICS, INC. · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7449202

    Compositions and methods for prostate and kidney health and disorders, an herbal preparation

    Integrated Chinese Medicine Holdings Ltd. · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7449323

    Hemorrhagic feline calicivirus

    The Regents of the University of California · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7449458

    Prodrugs of 2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7449201

    Storage stable power compositions of interleukin-4 receptor

    Nektar Therapeutics · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7449192

    Use of neurotoxin therapy for treatment of urologic and related disorders related to neurogenic bladder dysfunction

    The Regents of the University of Colorado · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7449182

    Therapeutic combination of a VEGF antagonist and anti-hypertensive agent

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7449171

    Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolic products

    The Regents of the University of California · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7449444

    Hydroxyethyl starch-containing polypeptide compositions

    The Regents of the University of Colorado · Granted Tue Nov 11 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. WO 2008137828

    MODÈLE DE MARQUEUR DE MATRICE ET PROCÉDÉS POUR ÉVALUER ET TRAITER L'ARTHRITE ET DES TROUBLES ASSOCIÉS

    CENTOCOR INC [US] · Granted Thu Nov 13 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 08 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7452723

    Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders

    ONCOLYTICS BIOTECH INC. · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7452971

    Compositions and methods for modifying toxic effects of proteinaceous compounds

    The Board of Regents of the University of Texas System · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7452995

    Aryl aniline β2 adrenergic receptor agonists

    Theravance, Inc. · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7452964

    Compositions and methods of use of targeting peptides against placenta and adipose tissues

    The Board of Regents of the University of Texas System · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7452898

    Phosphonate compounds

    The Regents of the University of California · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7452887

    Quinoline- and isoquinoline-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof

    Amphora Discovery Corporation · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7452873

    Inhibitors of GSK-3 and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7452865

    Antagonistic analogs of GH RH (2003)

    United States of America by Dept of Veterans Affairs · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7452861

    Use of an echinocandin antifungal agent in combination with a glycopeptide antibacterial agent

    Theravance, Inc. · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7452866

    Methods of inhibiting angiogenesis with fragments and homologs of troponin subunit 1

    Alseres Pharmaceuticals, Inc. · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7452879

    Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds

    Rigel Pharmaceuticals, Inc. · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7452538

    Death domain containing receptor 4 antibodies and methods

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7452679

    Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof

    Northwestern University · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7452681

    Diagnostic methods for the detection of autism spectrum disorder

    The Regents of the University of California · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7452548

    Conjugated linoleic acid compositions

    Aker Biomarine AS · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7452544

    Bacteriocins and novel bacterial strains

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Nov 18 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7455833

    Methods and compositions for treating viral infections using antibodies and immunoconjugates to aminophospholipids

    The Board of Regents of the University of Texas System · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 7455845

    Use of neurotoxin therapy for treatment of urologic and related disorders related to lowering elevated bladder pressure

    The Regents of the University of Colorado · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 7455964

    Genes from the 20q13 amplicon and their uses

    The Regents of the University of California · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7455994

    Methods for producing Marburg virus proteins

    The United States of America as represented by the Secretary of the Army · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 7456180

    Piperazine derivatives and their use as therapeutic agents

    Xenon Pharmaceuticals Inc. · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7456190

    Compositions useful as protein kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7456199

    Biphenyl compounds useful as muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7456203

    Muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 7456207

    Vaginal pharmaceutical compositions and methods for preparing them

    Teva Pharmaceuticals USA, Inc. · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 7456297

    Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7456268

    Materials and methods for inhibiting Wip1

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7456222

    Anti tubercular drug: compositions and methods

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7456162

    Benzofuran derivatives, their production and use

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7459426

    Methods of using IL-1 antagonists to treat autoinflammatory disease

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Dec 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7459534

    Inactivation resistant factor VIII

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2028?

624 published patents in our USPTO index have expiration dates falling in calendar year 2028.