Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2028

Annual patent cliff calendar for 2028 — US pharmaceutical patents by expiration date.

Patents
624

Quick answer

624 indexed pharmaceutical patents have expiration dates in 2028. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7432330

    Hydrolytically stable maleimide-terminated polymers

    Nektar Therapeutics AL, Corporation · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7432290

    Inhibitors of IMPDH enzyme

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7431929

    Use of vaccinia virus deleted for the E3L gene as a vaccine vector

    THE ARIZONA BOARD OF REGENTS · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7431942

    Orally disintegrable tablets

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7432304

    Small molecule antagonists of Bcl-2 family proteins

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7432349

    Tumor suppressor gene, p28ING5

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7432236

    Vasostatin as marrow protectant

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7432331

    Hydrolytically stable maleimide-terminated polymers

    Nektar Therapeutics AL, Corporation · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7432242

    Inhibitors of RGS proteins

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7431915

    Peptides whose uptake by cells is controllable

    The Regents of the University of California · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7432047

    Method for selective inactivation of viral replication

    Rigel Pharmaceuticals, Inc. · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7431931

    Compositions and method for preventing reactogenicity associated with administration of immunogenic live rotavirus compositions

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7435741

    2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Oct 14 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 09 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7435801

    Antibodies and other ligands directed against KIR2DL4 receptor for production of interferon gamma

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Oct 14 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 09 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7435814

    2,4-Pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Oct 14 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 09 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7435733

    Mineralocorticoid receptor modulator compounds and methods, and pharmaceutical compositions containing these compounds

    Ligand Pharmaceuticals Incorporated · Granted Tue Oct 14 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 09 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7435755

    CDDO-compounds and combination therapies thereof

    The Board of Regents of the University of Texas System · Granted Tue Oct 14 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 09 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7435742

    Quinuclidine derivatives and pharmaceutical compositions containing the same

    Laboratories Almirall, S.A. · Granted Tue Oct 14 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 09 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 2008255015

    COMPOSITION BASED ON GLYCEROL ETHER/POLYOL MIXTURES

    AIR LIQUIDE SANTE INT [FR] · Granted Thu Oct 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7439045

    pH controlled fermentation process for pseudomonic acid production

    TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7439323

    Cysteine-containing peptides having antioxidant properties

    The Regents of the University of California · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7439013

    Biocompatible polymer and filter for selectively eliminating leucocytes using the same

    ASAHI KASEI KURARAY MEDICAL CO., LTD. · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7439398

    Enantiomerically pure atomoxetine and tomoxetine mandelate

    Teva Pharmaceutical Fine Chemicals S.R.L. · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7439399

    Processes for the preparation of atomoxetine hydrochloride

    Teva Pharmaceutical Fine Chemicals S.R.L. · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7439373

    Crystalline mycophenolate sodium

    TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7439265

    Irciniastatins a and b

    ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7439249

    Inhibitors of phosphatases

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7439231

    Inhibitors of antigen presentation by MHC class II molecules and methods of use thereof

    Provid Pharmaceuticals Inc. · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7439226

    Serine protease inhibitors

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7439252

    Ascomycin crystalline forms and preparation thereof

    TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7439027

    Method for modulating process mediated by farnesoid activated receptors

    Ligand Pharmaceuticals Incorporated · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7438914

    Composition and method for enhancing immune response

    ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7438931

    Methods and compositions for the treatment of angiogenic diseases

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7438915

    Immunopotentiating effect of a Fomitella fraxinea-derived lectin on chicken immunity and resistance to coccidiosis

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Oct 21 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 7442372

    Delivery of therapeutic compounds to the brain and other tissues

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Oct 28 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 7442391

    Bioactive botanical cosmetic compositions and processes for their production

    INTEGRATED BOTANICAL TECHNOLOGIES, LLC · Granted Tue Oct 28 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7442543

    Mammalian selenoprotein differentially expressed in tumor cells

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Oct 28 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 7442546

    Method of modulating inflammatory response

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 28 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7442558

    Phthalamide-lanthanide complexes for use as luminescent markers

    The Regents of the University of California · Granted Tue Oct 28 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7442806

    Processes for preparing darifenacin hydrobromide

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Oct 28 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7442696

    Mineralocorticoid receptor modulator compounds, processes for their preparation, and their uses

    Ligand Pharmaceuticals Incorporated · Granted Tue Oct 28 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 7442790

    Caspase inhibitors and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 28 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 7442718

    Inhibitors of aspartyl protease

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 28 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7445628

    Method of treating a patient with a coated implantable medical device

    Cook Regentec LLC · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7445890

    Ucp-2 promoter and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7446112

    Modulators of muscarinic receptors

    Vertex Pharmaceuticals Incorporated · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7446108

    Tri-and tetraaza-acenaphthylen derivatives as CRF receptor antagonists

    Neurocrine, Inc. · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7446124

    Wortmannin analogs and methods of using same in combination with chemotherapeutic agents

    Arizona Board of Regents, Acting on Behalf of the University of Arizona · Granted Tue Nov 04 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2028?

624 published patents in our USPTO index have expiration dates falling in calendar year 2028.