Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2028

Annual patent cliff calendar for 2028 — US pharmaceutical patents by expiration date.

Patents
624

Quick answer

624 indexed pharmaceutical patents have expiration dates in 2028. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7419956

    Isolated physiologically active peptide and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7419991

    3-[5-(2-fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid, compositions, and methods for the use thereof

    PTC THERAPEUTICS, INC. · Granted Tue Sep 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7419957

    Peptides of melanoma antigen and their use in diagnostic, prophylactic and therapeutic methods

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Sep 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 28 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7423142

    Compositions and methods for inhibiting expression of anti-apoptotic genes

    Alnylam Pharmaceuticals, Inc. · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7423049

    Inhibitors of p38

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7422755

    Antimultiorganism glycoconjugate vaccine

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7422738

    Combined cancer treatment methods using antibodies to aminophospholipids

    The Board of Regents of the University of Texas System · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7423159

    Agent for preventing or treating neuropathy

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7423066

    Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism

    The Regents of the University of California · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7423015

    Antihelminthic drugs as a treatment for hyperproliferative diseases

    The Board of Regents of the University of Texas System · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7423043

    4-Piperidin-1-yl-7H-pyrrolo[2,3-d]pyrimidine compounds

    LEXICON PHARMACEUTICALS, INC. · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7422867

    Methods of identifying compounds that modulate IL-4 receptor mediated IgE synthesis utilizing a CLLD8 protein

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7422900

    System and method for forming a connective tissue construct

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7423118

    IAPS associated cell cycle proteins, compositions and methods of use

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 09 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7425449

    Site specific Listeria integration vectors and methods for using the same

    The Regents of the University of California · Granted Tue Sep 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7425329

    Methods for treating bone cancer pain by administering a nerve growth factor antagonist

    Regents of the University of Minnesota · Granted Tue Sep 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7425218

    Nitric oxide-releasing medical devices

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Sep 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7425644

    Method of purifying pravastatin

    TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság · Granted Tue Sep 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7425611

    Immunogenic HIV-1 multi-clade, multivalent constructs and methods of their use

    The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention · Granted Tue Sep 16 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7427671

    Compositions of alpha platelet derived growth factor receptor nucleic acid and protein and method of making

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7427639

    β2-adrenergic receptor agonists

    Theravance, Inc. · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7427602

    Sustained DNA delivery from structural matrices

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7427590

    Neurothrophic components of the ADNF I complex

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7427598

    Post-natal administration of activity-dependent neurotrophic factor-derived polypeptides for enhancing learning and memory

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7427496

    Anti-cancer compounds

    The Regents of the University of Colorado · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7427408

    Quorum sensing and biofilm formation

    The Regents of the University of California · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. CA 2626142

    SOLUTIONS AQUEUSES STABILISEES DE COMPOSES D'ERGOLINE

    AXXONIS PHARMA AG [DE] · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7427681

    Pyrazole compounds useful as protein kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7427630

    Condensed N-heterocyclic compounds and their use as CRF receptor antagonists

    Neurocrine Biosciences, Inc. · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7427394

    Biodegradable poly(β-amino esters) and uses thereof

    The United States of America as represented by the Secretary of the Army · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7427389

    Diagnostic agents for positron emission imaging using radiolabeled halogenated xanthenes

    Provectus Pharmatech, Inc. · Granted Tue Sep 23 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7429457

    Id-1 and Id-2 genes and products as markers of epithelial cancer

    The Regents of the University of California · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7429559

    Controlled release composition and method of producing the same

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7429562

    Cyclosporin analog formulations

    Isotechnika, Inc. · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 7429596

    1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof

    The Regents of the University of California · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 7429374

    Process for the measurement of the potency of glatiramer acetate

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7429387

    Use of botulinum toxin therapy for treatment of recalcitrant voiding dysfunction

    The Regents of the University of Colorado · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 7429571

    Therapeutic furopyrimidines and thienopyrimidines

    BioCryst Pharmaceuticals, Inc. · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7429238

    Systems and methods for the generation of crystalline polymorphs

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7429616

    Synthesis and complete stereochemical assignment of psymberin/irciniastatin for use as antitumor compounds

    The Board of Regents of the University of Texas System · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7429485

    Method of producing infectious reovirus

    ONCOLYTICS BIOTECH INC. · Granted Tue Sep 30 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 2008241252

    METHODS AND COMPOSITIONS FOR INTRAOCULAR ADMINISTRATION TO TREAT OCULAR CONDITIONS

    ALLERGAN INC [US] · Granted Thu Oct 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. CA 2682039

    PREPARATIONS COSMETIQUES VISANT A REDUIRE LA CELLULITE DISGRACIEUSE

    MENARINI FARMA IND [IT] · Granted Thu Oct 02 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7431932

    Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions

    ONCOLYTICS BIOTECH INC. · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7432067

    Methods of detection of MATER protein autoantibodies

    The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7432093

    Soluble, functional apoptotic protease-activating factor 1 fragments

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7432292

    Sulfhydantoins as phosphate isosteres

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7432300

    Gossypol co-crystals and the use thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Oct 07 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2028?

624 published patents in our USPTO index have expiration dates falling in calendar year 2028.