Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2027

Annual patent cliff calendar for 2027 — US pharmaceutical patents by expiration date.

Patents
599

Quick answer

599 indexed pharmaceutical patents have expiration dates in 2027. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 7220419

    Self-assembling recombinant papillomavirus capsid proteins

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 22 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7220730

    Cancer specific radiolabeled conjugates regulated by the cell cycle for the treatment and diagnosis of cancer

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue May 22 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7220745

    Heterocyclic compounds useful to treat HCV

    Rigel Pharmaceuticals, Inc. · Granted Tue May 22 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7220757

    Compositions and methods for topical administration of 2-NH-heteroarylimidazoles

    Replidyne, Inc. · Granted Tue May 22 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7220726

    Antifungal pimaricin compositions and therapeutic methods employing same

    The Board of Regents of the University of Texas System · Granted Tue May 22 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7220853

    Inhibition of chronic myelogenous leukemic cell growth by liposomal-antisense oligodeoxy-nucleotides targeting to Grb2 or Crk1

    The Board of Regents of the University of Texas System · Granted Tue May 22 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7220852

    Coronavirus isolated from humans

    The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention · Granted Tue May 22 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7220582

    Stem cells that transform to beating cardiomyocytes

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue May 22 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. EP 1786431

    VERBESSERTE PHOTOSENSITIZERFORMULIERUNGEN UND DEREN VERWENDUNG

    CERAMOPTEC IND INC [US] · Granted Wed May 23 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue May 18 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7223406

    Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder

    The Regents of the University of California · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7223836

    Peptides for chlamydophila pneumoniae vaccine and diagnosis

    The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7223787

    Prenylation inhibitors reduce host cell permissiveness to viral replication

    The Board of Regents of the University of Texas System · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7223783

    Indolinone derivatives

    Theravance, Inc. · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7223388

    Modified reoviral therapy

    The Board of Regents of the University of Texas System · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7223726

    Apolipoprotein A-I mutant proteins having cysteine substitutions and polynucleotides encoding same

    The Regents of the University of California · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7223571

    Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same

    The Board of Regents of the University of Oklahoma · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7223380

    Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging

    The Board of Regents of the University of Texas System · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7223424

    Compositions and methods for prostate and kidney health and disorders, an herbal preparation

    Integrated Chinese Medicine Holdings Ltd. · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7223791

    Function regulator for retinoid relative receptor

    Takeda Pharmaceutical Company Limited · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7223844

    Broadly cross-reactive neutralizing antibodies against human immunodeficiency virus selected by Env-CD4-co-receptor complexes

    THE UNITED STATES OF AMERICA, represented by the Secretary, Department of Health and Human Services · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7223853

    Secreted frizzled related protein fragments

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7223803

    Polyethylene (glycol) derivatives with proximal reactive groups

    Nektar Therapeutics AL, Corporation · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7223563

    Fibroblast growth factor (FGF23) nucleic acids

    Ludwig-Maximilians-Universitat Munchen · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7223585

    Viral purification methods

    ONCOLYTICS BIOTECH INC. · Granted Tue May 29 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7227009

    MT-SP1 polynucleotides and polypeptides

    Catalyst Biosciences, Inc. · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7227011

    Nucleic acid vaccines for prevention of flavivirus infection

    The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7226946

    Substituted phenol compounds useful for anesthesia and sedation

    Theravance, Inc. · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7226602

    Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7226588

    Non-toxic mutants of pathogenic gram-negative bacteria

    The Regents of the University of California · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7226609

    Sodium dodecyl sulfate compositions for inactivating prions

    The Regents of the University of California · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7226597

    Mutants of Clostridium difficile toxin B and methods of use

    The Board of Regents of the University of Oklahoma · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7226920

    Aminotriazole compounds useful as inhibitors of protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7226950

    Sodium channel modulators

    Theravance, Inc. · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7226991

    Phenylalanine derivatives

    THE UNITED STATES OF AMERICA, represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 7227010

    Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy

    The United States of America as represented by the Secretary of the Army · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 7226589

    Treatment of diseases by site specific instillation of cells or site specific transformation of cells and kits therefor

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 7226937

    Methods for modulating phototoxicity

    Board of Regents, University of Arizona · Granted Tue Jun 05 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 2007128117

    Ultrasound contrast agents and process for the preparation thereof

    BRACCO INT BV [NL] · Granted Thu Jun 07 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 02 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 7230086

    Assay for YKL-40 as a marker for degradation of mammalian connective tissue matrices

    The Regents of the University of California · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 7229995

    Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

    Neurocrine Biosciences, Inc. · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 7230004

    Cyclopamine analogues and methods of use thereof

    Infinity Discovery, Inc. · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 7229986

    Melanin-concentrating hormone antagonist

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 7229972

    3,6-Bicyclolides

    Enanta Pharmaceuticals, Inc. · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 7229627

    Apparatuses and methods for the production of haematophagous organisms and parasites suitable for vaccine production

    Sanaria Inc. · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 7229963

    Methods of using deacetylase inhibitors to promote cell differentiation and regeneration

    United States of America as represented by the Secretary of the Department of of Health Services, National Institutes of Health · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 7229641

    Rapid-melt compositions methods of making same and methods of using same

    Capricorn Pharma Inc. · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 7229770

    YKL-40 as a marker and prognostic indicator for cancers

    The Regents of the University of California · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 7229604

    Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging

    The Board of Regents of the University of Texas System · Granted Tue Jun 12 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 07 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2027?

599 published patents in our USPTO index have expiration dates falling in calendar year 2027.