Saturday, July 11, 2026

Drug profile · INN

zilucoplan

zilucoplan (ZILBRYSQ) is a complement c5 inhibitor.

EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L04) L04AJ06
Patents linked 0
Pipeline programs 6
News articles 0
Drug details — zilucoplan
Class
Antineoplastic and immunomodulating agents (L04)
Route
Patents
0
Programs
6
Data quality
0.83

Quick answer

zilucoplan (ZILBRYSQ) is a complement c5 inhibitor.

Key facts

INN zilucoplan
Brand ZILBRYSQ
Mechanism Complement C5 inhibitor
Target Complement C5
Therapeutic class Antineoplastic and immunomodulating agents (L04)
ATC code L04AJ06

Mechanism of action

Complement C5 inhibitor

Primary target: Complement C5

Approval history

Authority Status Date
EMA approved
TGA approved

Pipeline programs

  1. KYV101-006 Phase 3 · Kyverna Therapeutics · Generalized myasthenia gravis
  2. MG0014 Phase 3 · Anaxis Pharma · Generalized Myasthenia Gravis
  3. MG0015 Phase 3 · Anaxis Pharma · Generalized Myasthenia Gravis
  4. RA101495-02.302 Phase 3 · Anaxis Pharma · Generalized Myasthenia Gravis
  5. Zilucoplan sodium Phase 3 · Anaxis Pharma · Generalized Myasthenia Gravis
  6. DV0012 Phase 1 · Anaxis Pharma · Healthy Volunteers

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is zilucoplan?

zilucoplan (ZILBRYSQ) is a complement c5 inhibitor.

What is the brand name for zilucoplan?

ZILBRYSQ is a marketed brand name for zilucoplan. Check FDA Drugs@FDA for the current US label holder and prescribing information.