Friday, July 10, 2026

Drug profile · INN

zanidatamab

zanidatamab (ZIIHERA) is a receptor protein-tyrosine kinase erbb-2 inhibitor. Associated with Jazz Pharmaceuticals Ireland Limited.

EMA: approved Antineoplastic and immunomodulating agents (L01) L01FD07
Patents linked 0
Pipeline programs 13
News articles 0
Drug details — zanidatamab
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
13
Data quality
0.89

Quick answer

zanidatamab (ZIIHERA) is a receptor protein-tyrosine kinase erbb-2 inhibitor. Associated with Jazz Pharmaceuticals Ireland Limited.

Key facts

INN zanidatamab
Brand ZIIHERA
Mechanism Receptor protein-tyrosine kinase erbB-2 inhibitor
Target Receptor tyrosine-protein kinase erbB-2
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01FD07

Mechanism of action

Receptor protein-tyrosine kinase erbB-2 inhibitor

Primary target: Receptor tyrosine-protein kinase erbB-2

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. Zanidatamab Phase 3 · Jazz Pharmaceuticals Ireland · Biliary Tract Cancer
  2. Zanidatamab Phase 3 · BEONE MEDICINES AUS · Gastric Neoplasms
  3. Zanidatamab Phase 3 · Jazz Pharmaceuticals Ireland · Metastatic HER2-positive Breast Cancer
  4. 1479-0012 Phase 2 · Boehringer Ingelheim · gastroesophageal junction adenocarcinoma, metastatic gastric
  5. ZW25 (Zanidatamab) Phase 2 · BEONE MEDICINES AUS · HER2-amplified Biliary Tract Cancers
  6. ZW25 (Zanidatamab) Phase 2 · Jazz Pharmaceuticals Ireland · HER2-expressing Gastrointestinal Cancers, Including Gastroes
  7. ZW25 (Zanidatamab) Phase 2 · Jazz Pharmaceuticals Ireland · HER2+/HR+ Breast Cancer
  8. Zanidatamab Phase 2 · Jazz Pharmaceuticals Ireland · HER2-positive Breast Cancer

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is zanidatamab?

zanidatamab (ZIIHERA) is a receptor protein-tyrosine kinase erbb-2 inhibitor. Associated with Jazz Pharmaceuticals Ireland Limited.

What is the brand name for zanidatamab?

ZIIHERA is a marketed brand name for zanidatamab. Check FDA Drugs@FDA for the current US label holder and prescribing information.