Wednesday, July 8, 2026

Drug profile · INN

vonoprazan fumarate

vonoprazan fumarate (TAKECAB) is a potassium-transporting atpase inhibitor. Associated with Phathom Pharmaceuticals. Route of administration: oral. Current US regulatory status: approved.

FDA: approved PMDA: approved
US status approved
Patents linked 8
Pipeline programs 17
News articles 0
Drug details — vonoprazan fumarate
US status
approved
Class
Route
ORAL
Patents
8
Programs
17
Data quality
0.89

Quick answer

vonoprazan fumarate (TAKECAB) is a potassium-transporting atpase inhibitor. Associated with Phathom Pharmaceuticals. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN vonoprazan fumarate
Brand TAKECAB
Mechanism Potassium-transporting ATPase inhibitor
Target Potassium-transporting ATPase
Route ORAL
Formulation TABLET

Mechanism of action

Potassium-transporting ATPase inhibitor

Primary target: Potassium-transporting ATPase

Approval history

Authority Status Date
FDA approved
PMDA approved

Pipeline programs

  1. Vonoprazan Phase 3 · Phathom Pharmaceuticals · Erosive Esophagitis
  2. Vonoprazan Phase 3 · Phathom Pharmaceuticals · Non-Erosive Gastro-Esophageal Reflux Disease
  3. Vonoprazan Phase 3 · Takeda · Healthy Volunteers
  4. Vonoprazan Phase 3 · Takeda · Helicobacter Pylori
  5. Vonoprazan Phase 3 · Phathom Pharmaceuticals · Helicobacter Pylori Infection
  6. Vonoprazan Phase 2 · Phathom Pharmaceuticals · Eosinophilic Esophagitis
  7. Vonoprazan Phase 2 · Takeda · Gastroesophageal Reflux
  8. Vonoprazan Phase 1 · Phathom Pharmaceuticals · Healthy Participants

Related & competitor drugs

  1. dexlansoprazole Potassium-transporting ATPase inhibitor
  2. esomeprazole magnesium Potassium-transporting ATPase inhibitor
  3. lansoprazole Potassium-transporting ATPase inhibitor
  4. omeprazole Potassium-transporting ATPase inhibitor
  5. pantoprazole sodium Potassium-transporting ATPase inhibitor
  6. rabeprazole sodium Potassium-transporting ATPase inhibitor
  1. US 9198961

    Bacterial extract for digestive or urinary tract disorders and process for its preparation

    Expires Mon Nov 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9186411

    Pharmaceutical composition

    Expires Mon Nov 12 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9017743

    Bacterial extract for digestive or urinary tract disorders and process for its preparation

    Expires Mon Apr 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8236522

    Bacterial extract for digestive or urinary tract disorders and process for its preparation

    Expires Mon Aug 02 2032 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8173133

    Acyl pseudodipeptides which carry a functionalized auxiliary arm

    Expires Mon May 03 2032 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7977488

    1-heterocyclylsulfonyl, 2-aminomethyl, 5-(hetero-) aryl substituted 1-H-pyrrole derivatives as acid secretion inhibitors

    Expires Mon Jul 07 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7799762

    Acyl pseudodipeptides which carry a functionalised auxialiary arm

    Expires Mon Sep 16 2030 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7157092

    Acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same

    Expires Mon Dec 28 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is vonoprazan fumarate?

vonoprazan fumarate (TAKECAB) is a potassium-transporting atpase inhibitor. Associated with Phathom Pharmaceuticals. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for vonoprazan fumarate?

TAKECAB is a marketed brand name for vonoprazan fumarate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of vonoprazan fumarate?

vonoprazan fumarate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.